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Progress in the Surgical Treatment of Cardiac Arrhythmias: Title and subTitle BreakInitial Experience of 90 Patients FREE

Gerald M. Lawrie, MD; Christopher R. C. Wyndham, MD; Jack Krafchek, MD; Jerry C. Luck, MD; Robert Roberts, MD; Michael E. DeBakey, MD
[+] Author Affiliations

Reprint requests to Professor of Surgery, 1 Baylor Plaza, Houston, TX 77030 (Dr Lawrie).


JAMA. 1985;254(11):1464-1468. doi:10.1001/jama.1985.03360110054023
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Between 1981 and 1985, ninety patients were treated surgically for cardiac arrhythmias and have been followed for a mean interval of 21 months (range, one to 49 months). Follow-up is 100% complete. Fifty accessory pathways were divided in 35 patients (25 male and ten female; mean age, 35.2 years; range, 10 to 72 years), with no deaths. Five females, aged 10 to 35 years, were treated for focal atrial tachycardia, three for an atrial focus alone, and two with other arrhythmia procedures; four were cured and one was improved. Two patients (one man and one woman, both aged 33 years) had ablation of the atrioventricular node. Forty-one patients (32 male and nine female; average age, 56.9 years; range, 15 to 74 years) had ablation of ventricular tachycardia. Kent bundle division and focal atrial tachycardia ablation were also performed in two of these patients. More than 80% of patients had coronary disease. Mean preoperative ejection fraction was 33.9% with a range of 14% to 65%. Aneurysmectomy, endocardial resection, cryoablation, and coronary artery bypass were the procedures used. The perioperative mortality rate was 9.8% but there were no deaths in the last 23 patients. Ventricular tachycardia was abolished in all but three survivors in whom medical treatment is now effective. The automatic implantable defibrillator was implanted in 11 patients, with no surgical deaths. These results confirm the feasibility of relieving a variety of serious arrhythmias by surgical intervention.

(JAMA 1985;254:1464-1468)

REFERENCES

Gillette PC, Garson A, Hesslein PS, et al:  Successful surgical treatment of atrial, junctional and ventricular tachycardia unassociated with accessory connections in infants and children . Am Heart J 1981;;102:984-991.
Anderson KP, Stinson EB, Mason JW:  Surgical exclusion of focal paroxysmal atrial tachycardia . Am J Cardiol 1982;;49:869-874.
Yee R, Guiraudon GM, Gardner MJ, et al:  Refractory paroxysmal sinus tachycardia: Management by subtotal right atrial exclusion . J Am Coll Cardiol 1984;;3:400-404.
Cobb FR, Blumenschein SD, Sealy WC:  Successful surgical interruption of the bundle of Kent in a patient with Wolff-Parkinson-White syndrome . Circulation 1968;;38:1018-1029.
Sealy WC:  Direct surgery for arrhythmias . Chest 1982;;82:338-344.
Sealy WC, Mikat EM:  Anatomical problems with identification and interruption of posterior septal Kent bundles . Ann Thorac Surg 1983;; 36:584-595.
Ohkawa S-I, Haskel DB, Mikat EM, et al:  Anatomic effects of cryoablation of the atrioventricular conduction system . Circulation 1982;; 65:1155-1162.
Scheinman MM, Morady F, Hess DS, et al:  Catheter induced ablation of the atrioventricular junction to control refractory supraventricular arrhythmias . JAMA 1982;;248:851-855.
Sealy WC, Gallagher JJ, Kasell J:  His bundle interruption for control of inappropriate ventricular responses to atrial arrhythmias . Ann Thorac Surg 1981;;32:429-438.
Harken AH, Josephson ME, Horowitz LN:  Surgical endocardial resection for the treatment of malignant ventricular tachycardia . Ann Surg 1979;;190:456-460.
Josephson ME, Horowitz LN, Harken AH:  Endocardial excision: A new surgical technique for the treatment of ventricular tachycardia . Circulation 1979;;60:1430-1439.
Cox JL:  Anatomic-electrophysiologic basis for the surgical treatment of refractory ischemic ventricular tachycardia . Ann Surg 1983;;198:119-129.
Miller JM, Kienzle MG, Harken AH, et al:  Subendocardial resection for ventricular tachycardia: Predictors of surgical success . Circulation 1984;;70:624-631.
Mirowski M, Reid PR, Mower MM, et al:  Termination of malignant ventricular arrhythmias with an implanted automatic defibrillator in human beings . N Engl J Med 1980;;303:322-324.
Lawrie GM, Griffin JC, Wyndham CRC:  Epicardial implantation of the automatic implantable defibrillator by left subcostal thoracotomy . Pace 1984;;7:1370-1374.
Klein GJ, Guiraudon GM, Perkins DG, et al:  Surgical correction of the Wolff-Parkinson-White syndrome in the closed heart using cryosurgery: A simplified approach . J Am Coll Cardiol 1984;;3:405-409.
Iwa T, Magara T, Watanabe Y, et al:  Interruption of multiple accessory conduction pathways in the Wolff-Parkinson-White syndrome . Ann Thorac Surg 1980;;30:313-325.
Krafchek J, Lawrie GM, Wyndham CRC:  Cryo-ablation of arrhythmias from the interventricular septum: Initial experience with a new biventricular approach . J Thorac Cardiovasc Surg , in press.
Brodman R, Fisher JD:  Evaluation of a catheter technique for ablation of accessory pathways near the coronary sinus using a canine model . Circulation 1983;;67:923-929.

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Gillette PC, Garson A, Hesslein PS, et al:  Successful surgical treatment of atrial, junctional and ventricular tachycardia unassociated with accessory connections in infants and children . Am Heart J 1981;;102:984-991.
Anderson KP, Stinson EB, Mason JW:  Surgical exclusion of focal paroxysmal atrial tachycardia . Am J Cardiol 1982;;49:869-874.
Yee R, Guiraudon GM, Gardner MJ, et al:  Refractory paroxysmal sinus tachycardia: Management by subtotal right atrial exclusion . J Am Coll Cardiol 1984;;3:400-404.
Cobb FR, Blumenschein SD, Sealy WC:  Successful surgical interruption of the bundle of Kent in a patient with Wolff-Parkinson-White syndrome . Circulation 1968;;38:1018-1029.
Sealy WC:  Direct surgery for arrhythmias . Chest 1982;;82:338-344.
Sealy WC, Mikat EM:  Anatomical problems with identification and interruption of posterior septal Kent bundles . Ann Thorac Surg 1983;; 36:584-595.
Ohkawa S-I, Haskel DB, Mikat EM, et al:  Anatomic effects of cryoablation of the atrioventricular conduction system . Circulation 1982;; 65:1155-1162.
Scheinman MM, Morady F, Hess DS, et al:  Catheter induced ablation of the atrioventricular junction to control refractory supraventricular arrhythmias . JAMA 1982;;248:851-855.
Sealy WC, Gallagher JJ, Kasell J:  His bundle interruption for control of inappropriate ventricular responses to atrial arrhythmias . Ann Thorac Surg 1981;;32:429-438.
Harken AH, Josephson ME, Horowitz LN:  Surgical endocardial resection for the treatment of malignant ventricular tachycardia . Ann Surg 1979;;190:456-460.
Josephson ME, Horowitz LN, Harken AH:  Endocardial excision: A new surgical technique for the treatment of ventricular tachycardia . Circulation 1979;;60:1430-1439.
Cox JL:  Anatomic-electrophysiologic basis for the surgical treatment of refractory ischemic ventricular tachycardia . Ann Surg 1983;;198:119-129.
Miller JM, Kienzle MG, Harken AH, et al:  Subendocardial resection for ventricular tachycardia: Predictors of surgical success . Circulation 1984;;70:624-631.
Mirowski M, Reid PR, Mower MM, et al:  Termination of malignant ventricular arrhythmias with an implanted automatic defibrillator in human beings . N Engl J Med 1980;;303:322-324.
Lawrie GM, Griffin JC, Wyndham CRC:  Epicardial implantation of the automatic implantable defibrillator by left subcostal thoracotomy . Pace 1984;;7:1370-1374.
Klein GJ, Guiraudon GM, Perkins DG, et al:  Surgical correction of the Wolff-Parkinson-White syndrome in the closed heart using cryosurgery: A simplified approach . J Am Coll Cardiol 1984;;3:405-409.
Iwa T, Magara T, Watanabe Y, et al:  Interruption of multiple accessory conduction pathways in the Wolff-Parkinson-White syndrome . Ann Thorac Surg 1980;;30:313-325.
Krafchek J, Lawrie GM, Wyndham CRC:  Cryo-ablation of arrhythmias from the interventricular septum: Initial experience with a new biventricular approach . J Thorac Cardiovasc Surg , in press.
Brodman R, Fisher JD:  Evaluation of a catheter technique for ablation of accessory pathways near the coronary sinus using a canine model . Circulation 1983;;67:923-929.
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