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May 3, 1985, Vol 253, No. 17 >
ARTICLE | May 3, 1985

Treatment of Unstable Angina FREE

Herbert N. Hultgren, MD; John C. Giacomini, MD; Craig Miller, MD
[+] Author Affiliations

This article is one of a series sponsored by the American Heart Association.

Reprint requests to Cardiology Service (111C), Veterans Administration Medical Center, 3801 Miranda Ave, Palo Alto, CA 94304 (Dr Hultgren).


JAMA. 1985;253(17):2555-2557. doi:10.1001/jama.1985.03350410121031
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References

MAJOR presentations of coronary artery disease include sudden death, myocardial infarction, stable angina, unstable angina, and miscellaneous syndromes such as arrhythmias and left ventricular failure. While the prevalence of unstable angina is relatively low compared with other coronary disease syndromes, the potential for prevention of infarction and death is high, hence the importance of this review of current therapy.

Clinical Presentations  Two general presentations of unstable angina may occur: type I—(a) stable angina with a recent increase in frequency and severity of attacks, (b) recent onset angina with increasing frequency and severity of episodes; or type II—recent onset of rest angina of prolonged duration (usually >15 minutes), little relief from nitrates, and often associated with ST-T-wave changes, sweating, nausea, and other constitutional symptoms.The relative frequency of these presentations may vary. In a prospective study from this hospital, 62% of 228 patients with unstable angina had prior stable angina (type

REFERENCES

1 +
Hultgren H, Shettiger W, Miller C:  Medical versus surgical treatment of unstable angina . Am J Cardiol 1982;;50:663-670.
2 +
Gazes P, Mobley E, Farris H, et al:  Preinfarctional (unstable) angina: A prospective study—ten year follow up . Circulation 1983;; 48:331-337.
3 +
Mandelson J, Wolf N, Singh S, et al:  Intracoronary thrombus in nontransmural myocardial infarction and unstable angina pectoris . Am J Cardiol 1983;;52:1-6.
4 +
Moise A, Theroux P, Taeymans Y, et al:  Unstable angina and progression of coronary atherosclerosis . N Engl J Med 1983;;309:685-689.
5 +
Cooperative Unstable Angina Study Group:  Unstable angina pectoris: National cooperative study group to compare surgical and medical therapy. In hospital experience and initial follow up results in patients with one, two and three vessel disease . Am J Cardiol 1978;;42:839-848.
6 +
Olson H, Lyons K, Butman S, et al:  Validation of technetium-99 stannous pyrophosphate myocardial scintigraphy for diagnosing acute myocardial infarction more than 48 hours old when serum creatine kinase-MB has returned to normal . Am J Cardiol 1983;;52:245-251.
7 +
Lewis D, Davis J, Archibald D, et al:  Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina: Results of a Veterans Administration cooperative study . N Engl J Med 1983;; 309:396-403.
8 +
Takaro T, Hultgren H, Detre K, et al:  The Veterans Administration cooperative study of stable angina: Current Status . Circulation 1982;; 65( (suppl 2) ):60-67.
9 +
European Coronary Surgery Study Group:  Long-term results of prospective randomized study of coronary artery bypass surgery in stable angina pectoris . Lancet 1982;;2:1173-1180.
10 +
Detre K, Peduzzi P, Murphy M, et al:  Effect of bypass surgery on survival of patients in low and high risk subgroups delineated by the use of simple clinical variables . Circulation 1981;;63:1329-1338.
11 +
Nixon D, Detre K, McCabe C, et al:  Role of PTCA in treatment of unstable angina . Am J Cardiol 1984;;53:131C-135C.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Hultgren H, Shettiger W, Miller C:  Medical versus surgical treatment of unstable angina . Am J Cardiol 1982;;50:663-670.
2 +
Gazes P, Mobley E, Farris H, et al:  Preinfarctional (unstable) angina: A prospective study—ten year follow up . Circulation 1983;; 48:331-337.
3 +
Mandelson J, Wolf N, Singh S, et al:  Intracoronary thrombus in nontransmural myocardial infarction and unstable angina pectoris . Am J Cardiol 1983;;52:1-6.
4 +
Moise A, Theroux P, Taeymans Y, et al:  Unstable angina and progression of coronary atherosclerosis . N Engl J Med 1983;;309:685-689.
5 +
Cooperative Unstable Angina Study Group:  Unstable angina pectoris: National cooperative study group to compare surgical and medical therapy. In hospital experience and initial follow up results in patients with one, two and three vessel disease . Am J Cardiol 1978;;42:839-848.
6 +
Olson H, Lyons K, Butman S, et al:  Validation of technetium-99 stannous pyrophosphate myocardial scintigraphy for diagnosing acute myocardial infarction more than 48 hours old when serum creatine kinase-MB has returned to normal . Am J Cardiol 1983;;52:245-251.
7 +
Lewis D, Davis J, Archibald D, et al:  Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina: Results of a Veterans Administration cooperative study . N Engl J Med 1983;; 309:396-403.
8 +
Takaro T, Hultgren H, Detre K, et al:  The Veterans Administration cooperative study of stable angina: Current Status . Circulation 1982;; 65( (suppl 2) ):60-67.
9 +
European Coronary Surgery Study Group:  Long-term results of prospective randomized study of coronary artery bypass surgery in stable angina pectoris . Lancet 1982;;2:1173-1180.
10 +
Detre K, Peduzzi P, Murphy M, et al:  Effect of bypass surgery on survival of patients in low and high risk subgroups delineated by the use of simple clinical variables . Circulation 1981;;63:1329-1338.
11 +
Nixon D, Detre K, McCabe C, et al:  Role of PTCA in treatment of unstable angina . Am J Cardiol 1984;;53:131C-135C.

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