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ARTICLE |

Total Artificial Heart Implantation— Eligibility Criteria FREE

Robert J. Levine, MD
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Address editorial communications to the Editor, 535 N Dearborn St, Chicago, IL 60610.


JAMA. 1984;252(11):1458-1459. doi:10.1001/jama.1984.03350110058032
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"What do you think of Barney Clark's great sacrifice—his willingness to serve as a subject of risky research so near the end of his life?" My response surprised the journalist who asked me this question shortly after the implantation of a total artificial heart in Dr Clark. "Considering the alternatives, as I understand the alternatives available to him," I replied, "I think he made an easily understandable choice. He chose a chance of life over a certainty of death. That does not sound like a sacrifice to me."

In the September issue of the Archives of General Psychiatry, Berenson and Grosser1 present a careful account of Dr Clark's relevant experiences before and after he received his artificial heart; it is particularly rich in neuropsychiatric detail. From this report we learn that Dr Clark wanted first and foremost an improvement in his physical condition. Even before he knew of the

REFERENCES

Berenson CK, Grosser BI:  Total artificial heart implantation . Arch Gen Psychiatry 1984;;41:910-916.
The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research , Dept of Health, Education, and Welfare publication (OS) 78-0012. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, 1978;.
Securing Access to Health Care: The Ethical Implications of Differences in the Availability of Health Services , publication 0-401-553 QL3. President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research, 1983;.
Levine RJ: Ethics and Regulation of Clinical Research . Baltimore, Urban & Schwarzenberg, 1981;.
The Artificial Heart Assessment Panel of the National Heart and Lung Institute: The Totally Implantable Artificial Heart , Dept of Health, Education, and Welfare publication (NIH) 74-191. National Institutes of Health, 1973;.
Woolley FR:  Ethical issues in the implantation of the total artificial heart . N Engl J Med 1984;;310:292-296.
Christopherson LK:  Heart transplants . Hastings Cent Rep 1982;;12:18-21.

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Berenson CK, Grosser BI:  Total artificial heart implantation . Arch Gen Psychiatry 1984;;41:910-916.
The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research , Dept of Health, Education, and Welfare publication (OS) 78-0012. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, 1978;.
Securing Access to Health Care: The Ethical Implications of Differences in the Availability of Health Services , publication 0-401-553 QL3. President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research, 1983;.
Levine RJ: Ethics and Regulation of Clinical Research . Baltimore, Urban & Schwarzenberg, 1981;.
The Artificial Heart Assessment Panel of the National Heart and Lung Institute: The Totally Implantable Artificial Heart , Dept of Health, Education, and Welfare publication (NIH) 74-191. National Institutes of Health, 1973;.
Woolley FR:  Ethical issues in the implantation of the total artificial heart . N Engl J Med 1984;;310:292-296.
Christopherson LK:  Heart transplants . Hastings Cent Rep 1982;;12:18-21.
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To understand the clinical management of acute heart failure syndromes.
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