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August 17, 1984, Vol 252, No. 7 >
ARTICLE | August 17, 1984

Monosodium Glutamania: The Chinese Restaurant Syndrome Revisited FREE

John W. Cochran, MD; Arlene H. Cochran
JAMA. 1984;252(7):899-899. doi:10.1001/jama.1984.03350070017009
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To the Editor.—  There are numerous reports of the Chinese restaurant syndrome (CRS) in the literature. This is a symptom complex consisting of burning, tightness, and numbness of the neck and face, occasionally accompanied by dizziness, headache, nausea, and vomiting occurring after eating Chinese food.1-3 One pediatric case is reported in which an 18-month-old child began crying and apparently suffered abdominal pain ten minutes after eating wonton soup.4 No case reports describe delirium associated with Chinese food or wonton soup.

Report of a Case.—  On three separate occasions after eating Chinese food at the same restaurant, our 3-year-old daughter had a 30- to 45-minute episode of inappropriate behavior, confusion, and slight ataxia of gait without nystagmus, headache, nausea, vomiting, or abdominal pain. On each occasion, she had eaten wonton soup accompanied by a cola. These symptoms began before she had completed the soup. She giggled and talked "baby

REFERENCES

1 +
Kwok RHM:  Chinese-restaurant syndrome . N Engl J Med 1968;;278:796.
2 +
Schaumburg H, Byck R:  Sin cib-syn: Accent on glutamate . N Engl J Med 1968;;279:105.
3 +
Schaumburg H, Byck R, Gerstl R, et al:  Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome . Science 1969;;163:826.
4 +
Asnes RS:  Chinese restaurant syndrome in an infant . Clin Pediatr 1969;;19:705-706.
5 +
Young AB, Penney JB, Dauth GW, et al:  Glutamate or aspartate as a possible neurotransmitter of cerebral corticofugal fibers in the monkey . Neurology 1983;; 33:1513-1516.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Kwok RHM:  Chinese-restaurant syndrome . N Engl J Med 1968;;278:796.
2 +
Schaumburg H, Byck R:  Sin cib-syn: Accent on glutamate . N Engl J Med 1968;;279:105.
3 +
Schaumburg H, Byck R, Gerstl R, et al:  Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome . Science 1969;;163:826.
4 +
Asnes RS:  Chinese restaurant syndrome in an infant . Clin Pediatr 1969;;19:705-706.
5 +
Young AB, Penney JB, Dauth GW, et al:  Glutamate or aspartate as a possible neurotransmitter of cerebral corticofugal fibers in the monkey . Neurology 1983;; 33:1513-1516.

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