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August 3, 1984, Vol 252, No. 5 >
ARTICLE | August 3, 1984

Premature Ventricular Complexes: Title and subTitle BreakDiagnosis and Indications for Therapy FREE

Joel Morganroth, MD
[+] Author Affiliations

This article is one of a series sponsored by the American Heart Association.

Reprint requests to Likoff Cardiovascular Institute, Hahnemann University Hospital, 230 N Broad St, Philadelphia, PA 19102 (Dr Morganroth).


JAMA. 1984;252(5):673-676. doi:10.1001/jama.1984.03350050061030
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References

APPROXIMATELY every minute in the United States, one person dies of sudden cardiac death. This accounts for more than one half of all deaths due to coronary artery disease, a disease that also commonly displays the syndromes of angina pectoris and acute myocardial infarction. Of the approximately 1.25 million Americans who have an acute myocardial infarction per year, more than one half die before reaching a medical facility, and of those who survive hospitalization, approximately 10% or more will be dead in the first year. Half of this mortality will be caused by sudden cardiac death. Sudden cardiac death is the leading cause of death in the 20- to 64-year-old age range and has the most dramatic social, psychological, and economical impact of any disease, particularly since it occurs prematurely in life, usually without warning or clear precipitating factor.

Studies in individuals who have sudden cardiac death while fortuitously wearing

REFERENCES

1 +
Panidis I, Morganroth J:  Holter monitoring during cardiac sudden death: Clues to its etiology and prevention . J Am Coll Cardiol 1983;; 2:798-805.
2 +
Cobb LA, Hallstrom AP:  Community-based cardiopulmonary resuscitation: What have we learned?  in Greenberg HM, Dwyer EM (eds): Sudden Coronary Death . New York, New York Academy of Sciences, 1982;, pp 330-332.
3 +
Schulze RA, Strauss HW, Pitt B:  Sudden death in the year following myocardial infarction: Relation to ventricular premature contractions in the late hospital phase and left ventricular ejection fraction . Am J Med 1977;;62:192-199.
4 +
Bigger JT, Weld FM, Rolinitsky MS:  Prevalence of characteristics and significance of ventricular tachycardia (three or more complexes) detected with ambulatory electrocardiographic recordings in the late hospital phase of acute myocardial infarction . Am J Cardiol 1981;;48:815-823.
5 +
Follansbee WP, Michelson EL, Morganroth J:  Nonsustained ventricular tachycardia in ambulatory patients: Characteristics and association with sudden cardiac death . Ann Intern Med 1980;;92:741-747.
6 +
Moss AJ, Davis HT, DeCamilla J, et al:  Ventricular ectopic beats and their relation to sudden and nonsudden cardiac death after myocardial infarction . Circulation 1979;;60:998-1003.
7 +
Morganroth J:  How to evaluate a new antiarrhythmic drug: The challenge of sudden cardiac death , in Morganroth J, Moore EN, Michelson EL, et al (eds): The Evaluation of New Antiarrhythmic Drugs . The Hague, Martinus Nijhoff Publishers Inc, 1981;, pp 1-5.
8 +
Horowitz LN, Josephson ME, Farshidi A, et al:  Recurrent sustained ventricular tachycardia: III. Role of electrophysiologic study in selection of antiarrhythmic regimens . Circulation 1978;; 58:986-997.
9 +
Ruskin JN, DiMarco JP, Garan H:  Out-of-hospital cardiac arrest: Electrophysiologic observations and selection of long-term antiarrhythmic therapy . N Engl J Med 1980;;303:607-613.
10 +
Kostis JB, McCrone K, Moreya AE, et al:  Premature ventricular complexes in the absence of identifiable heart disease . Circulation 1981;; 63:1351-1356.
11 +
Morganroth J, Michelson EL, Horowitz LN, et al:  Limitations of routine long-term electrocardiographic monitoring to assess ventricular ectopic frequency . Circulation 1978;; 58:408-414.
12 +
Graboys TB, Lown B, Podrid PJ, et al:  Long-term survival of patients with malignant ventricular arrhythmia treated with antiarrhythmic drugs . Am J Cardiol 1982;;50:437-443.
13 +
Lichstein E, Morganroth J, Harrist R, et al:  Effect of propranolol on ventricular arrhythmia: The beta-blocker heart attack experience . Circulation 1983;;67:15-111.
14 +
Morganroth J, Lichstein E, Hubble E, et al:  Reduction of chronic ventricular arrhythmias and sudden death in patients post myocardial infarction , abstracted. Clin Res 1983;;31:207.

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1 +
Panidis I, Morganroth J:  Holter monitoring during cardiac sudden death: Clues to its etiology and prevention . J Am Coll Cardiol 1983;; 2:798-805.
2 +
Cobb LA, Hallstrom AP:  Community-based cardiopulmonary resuscitation: What have we learned?  in Greenberg HM, Dwyer EM (eds): Sudden Coronary Death . New York, New York Academy of Sciences, 1982;, pp 330-332.
3 +
Schulze RA, Strauss HW, Pitt B:  Sudden death in the year following myocardial infarction: Relation to ventricular premature contractions in the late hospital phase and left ventricular ejection fraction . Am J Med 1977;;62:192-199.
4 +
Bigger JT, Weld FM, Rolinitsky MS:  Prevalence of characteristics and significance of ventricular tachycardia (three or more complexes) detected with ambulatory electrocardiographic recordings in the late hospital phase of acute myocardial infarction . Am J Cardiol 1981;;48:815-823.
5 +
Follansbee WP, Michelson EL, Morganroth J:  Nonsustained ventricular tachycardia in ambulatory patients: Characteristics and association with sudden cardiac death . Ann Intern Med 1980;;92:741-747.
6 +
Moss AJ, Davis HT, DeCamilla J, et al:  Ventricular ectopic beats and their relation to sudden and nonsudden cardiac death after myocardial infarction . Circulation 1979;;60:998-1003.
7 +
Morganroth J:  How to evaluate a new antiarrhythmic drug: The challenge of sudden cardiac death , in Morganroth J, Moore EN, Michelson EL, et al (eds): The Evaluation of New Antiarrhythmic Drugs . The Hague, Martinus Nijhoff Publishers Inc, 1981;, pp 1-5.
8 +
Horowitz LN, Josephson ME, Farshidi A, et al:  Recurrent sustained ventricular tachycardia: III. Role of electrophysiologic study in selection of antiarrhythmic regimens . Circulation 1978;; 58:986-997.
9 +
Ruskin JN, DiMarco JP, Garan H:  Out-of-hospital cardiac arrest: Electrophysiologic observations and selection of long-term antiarrhythmic therapy . N Engl J Med 1980;;303:607-613.
10 +
Kostis JB, McCrone K, Moreya AE, et al:  Premature ventricular complexes in the absence of identifiable heart disease . Circulation 1981;; 63:1351-1356.
11 +
Morganroth J, Michelson EL, Horowitz LN, et al:  Limitations of routine long-term electrocardiographic monitoring to assess ventricular ectopic frequency . Circulation 1978;; 58:408-414.
12 +
Graboys TB, Lown B, Podrid PJ, et al:  Long-term survival of patients with malignant ventricular arrhythmia treated with antiarrhythmic drugs . Am J Cardiol 1982;;50:437-443.
13 +
Lichstein E, Morganroth J, Harrist R, et al:  Effect of propranolol on ventricular arrhythmia: The beta-blocker heart attack experience . Circulation 1983;;67:15-111.
14 +
Morganroth J, Lichstein E, Hubble E, et al:  Reduction of chronic ventricular arrhythmias and sudden death in patients post myocardial infarction , abstracted. Clin Res 1983;;31:207.

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