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ARTICLE |

Treatment of Intraepithelial Neoplasia FREE

Paul D. Indman, MD
JAMA. 1984;251(4):470-470. doi:10.1001/jama.1984.03340280026017
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To the Editor.—  In a recent QUESTIONS AND ANSWERS column,1 the use of the CO2 laser in the treatment of cervical intraepithelial neoplasia (CIN) is discussed. There are several misconceptions that need to be clarified.First, the term laser cautery is used more than once. When used at high power densities, the CO2 laser causes vaporization of tissue, resulting in its removal. While there is some thermal damage to the underlying tissue, this is minimal, and less than 1 mm deep. In contrast, hot or cold cautery results in necrosis to an unknown depth of tissue, rather than the actual removal of tissue. Laser treatment of CIN is, therefore, more comparable with conization than cauterization.Two basic types of laser conizations may be done. In the vaporization cone, the entire transformation zone is vaporized to a measured depth of at least 6 mm. In this type of

REFERENCES

 CO2 laser treatment of gynecologic malignant neoplasms . JAMA 1983;;250:672.
Wright VC, Davies E, Riopelle MA:  Laser surgery for cervical intraepithelial neoplasia: Principles and results . Am J Obstet Gynecol 1983;;145:181.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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 CO2 laser treatment of gynecologic malignant neoplasms . JAMA 1983;;250:672.
Wright VC, Davies E, Riopelle MA:  Laser surgery for cervical intraepithelial neoplasia: Principles and results . Am J Obstet Gynecol 1983;;145:181.
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