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To the Editor.— Measurement of serum creatinine concentration is the best of the widely available clinical means of assessing glomerular function. However, there are a number of pitfalls that must be taken into account when evaluating glomerular filtration by creatinine level measurements.1 One of these pitfalls is the spurious interference by a variety of endogenous and exogenous metabolites.2 The interference by bilirubin in the measurement of serum creatinine levels has been recognized in the technical literature for several years3-5; however, its clinical implication has received little or no attention. We describe a patient who had discordant values for serum creatinine during his hospital stay. We also investigated bilirubin interference with creatinine level measurement by various methods.
Report of a Case.— A 34-year-old man with decompensated alcoholic cirrhosis experienced oliguria two days after admission to the hospital. Relevant laboratory findings included the following measurements in serum: sodium, 135
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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