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ARTICLE |

Sodium and Blood Pressure in Infancy FREE

Julie R. Ingelfinger, MD
JAMA. 1983;250(3):389-390. doi:10.1001/jama.1983.03340030049030
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Fifteen years have elapsed since Louis Dahl published "Salt in Processed Baby Foods," an editorial concerning the detrimental effects of sodium added to baby food.1 Despite a large body of data linking high sodium intake to hypertension, little direct information about the effects of sodium in infant foods has been available.2-5 Finally, in this issue of The Journal (p 370), Hofman and colleagues have shown in a randomized trial that 231 normal infants fed a low-salt diet have statistically lower systolic blood pressures at the end of six months than do 245 normal control infants. Although follow-up past the six-month end point of the study has not yet occurred, the findings are a welcome addition to the sodium-blood pressure story. American baby food manufacturers will likely be pleased that they have already followed the voluntary guidelines of the Food and Drug Administration and removed extra salt from their

REFERENCES

Dahl LK:  Salt in processed baby foods . Am J Clin Nutr 1968;;21:787-792.
Blumenthal S. Epps RP. Heavenrich R, et al:  Report of the Task Force on Blood Pressure Control in Children . Pediatrics 1977;;59( (suppl 5) ):797-819.
Szklo M:  Epidemiologic patterns of blood pressure in children . Epidemiol Rev 1979;;1:143-169.
Whitten CF, Stewart RA:  The effect of dietary sodium in infancy on blood pressure and related factors . Acta Paediatr Scand 1980;;( (suppl 279) ):1-17.
Uhari M. Timonen E:  Dietary salt and blood pressure during the first four months of life , in Giovanelli G, New MI, Gorini S (eds): Hypertension in Children and Adolescents . New York, Raven Press, 1981;. pp 287-291.
McCarron DA, Filer LJ, Van Itallie TV:  Current perspectives in hypertension: A symposium on food, nutrition and health . Hypertension 1982;;4( (suppl 3) ):III-1-III-183.
Garay RP, Elghozi JL. Dagher G:  Laboratory distinction between essential and secondary hypertension by measurement of erythrocyte cation fluxes . N Engl J Med 1980;;302:769-771.
Canessa M, Adragna N. Solomon HS, et al:  Increased sodium-lithium countertransport in red cells of patients with essential hypertension . N Engl J Med 1980;;307:772-776.
Parfrey PS, van den Burg MJ, Wright P, et al:  Blood pressure and hormonal changes following alteration in dietary sodium and potassium in mild essential hypertension . Lancet 1981;;1:59-63.
McCarron DA:  Low serum concentrations of ionized calcium in patients with hypertension . N Engl J Med 1982;;307:226-228.
Chrysant SG, Whong R, Dillard BL, et al:  Incidence and significance of hypomagnesemia in treated ambulatory hypertensive patients . Kidney Int 1981;;19:164.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Dahl LK:  Salt in processed baby foods . Am J Clin Nutr 1968;;21:787-792.
Blumenthal S. Epps RP. Heavenrich R, et al:  Report of the Task Force on Blood Pressure Control in Children . Pediatrics 1977;;59( (suppl 5) ):797-819.
Szklo M:  Epidemiologic patterns of blood pressure in children . Epidemiol Rev 1979;;1:143-169.
Whitten CF, Stewart RA:  The effect of dietary sodium in infancy on blood pressure and related factors . Acta Paediatr Scand 1980;;( (suppl 279) ):1-17.
Uhari M. Timonen E:  Dietary salt and blood pressure during the first four months of life , in Giovanelli G, New MI, Gorini S (eds): Hypertension in Children and Adolescents . New York, Raven Press, 1981;. pp 287-291.
McCarron DA, Filer LJ, Van Itallie TV:  Current perspectives in hypertension: A symposium on food, nutrition and health . Hypertension 1982;;4( (suppl 3) ):III-1-III-183.
Garay RP, Elghozi JL. Dagher G:  Laboratory distinction between essential and secondary hypertension by measurement of erythrocyte cation fluxes . N Engl J Med 1980;;302:769-771.
Canessa M, Adragna N. Solomon HS, et al:  Increased sodium-lithium countertransport in red cells of patients with essential hypertension . N Engl J Med 1980;;307:772-776.
Parfrey PS, van den Burg MJ, Wright P, et al:  Blood pressure and hormonal changes following alteration in dietary sodium and potassium in mild essential hypertension . Lancet 1981;;1:59-63.
McCarron DA:  Low serum concentrations of ionized calcium in patients with hypertension . N Engl J Med 1982;;307:226-228.
Chrysant SG, Whong R, Dillard BL, et al:  Incidence and significance of hypomagnesemia in treated ambulatory hypertensive patients . Kidney Int 1981;;19:164.
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