To the Editor.— The report of Mitchell et al on the adverse effects of computed tomographic (CT) scan premedication in children (1982;247:2385) was both informative and disturbing. Surely an adverse reaction rate of 13% is uncomfortably high; more unsettling, however, is the fact that so many of these reactions were associated with excessive doses, multiple medications, or both. The choice of premedication in a teaching hospital is usually left to the house officer and is often variable, arbitrary, and dictated by personal or anecdotal experience; the results may be bad.I offer two suggestions. First, more studies like this one are urgently needed. Perhaps the Food and Drug Administration could use established mechanisms of adverse-effect reporting to gather data on current practices and hazards of premedication in children who undergo CT scans, cardiac catheterization, or minor surgery.Second, the responsibility for choosing premedication regimens should not lie with the resident—at
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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