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ARTICLE |

Effectiveness of Differential Leukocyte Count in Case Finding in the Ambulatory Care Setting FREE

Eugene C. Rich, MD; Terry W. Crowson, MD; Donald P. Connelly, MD, PhD
[+] Author Affiliations

Reprint requests to Department of Medicine, St Paul-Ramsey Medical Center, 640 Jackson St, St Paul, MN 55101 (Dr Rich).


JAMA. 1983;249(5):633-636. doi:10.1001/jama.1983.03330290055029
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The value of the differential leukocyte count in case finding in the ambulatory care setting was evaluated by retrospectively reviewing 799 encounters resulting in complete blood cell counts. Four hundred seventy-five differential leukocyte counts, of which 63 were abnormal, met criteria for case finding. No clinically inapparent disease was discovered through the use of these tests. These data suggest that the quantitative cell counts of the differential leukocyte examination may be of no value in case finding in the ambulatory care setting.

(JAMA 1983;249:633-636)

REFERENCES

Fineberg HV:  Clinical chemistries: The high cost of low cost diagnostic tests , in Altman SH, Blendon R (eds): Medical Technology: The Culprit Behind Health Care Costs? , publication (PHS) 79-3216. US Dept of Health, Education, and Welfare, 1979;, pp 144-165.
Moloney TW, Rogers DE:  Medical technology: A different view of the contentious debate over costs . N Engl J Med 1979;;301:1413-1429.
Canadian Task Force:  The periodic health examination . Can Med Assoc J 1979;;121:1193-1254.
Sackett DL, Holland WW:  Controversy in the detection of disease . Lancet 1975;;2:357-359.
Schneiderman LJ, DeSalvo L, Baylor S, et al:  The abnormal screening laboratory results . Arch Intern Med 1972;;129:88-90.
Korvin CC, Pearce RH, Stanley J:  Admissions screening: Clinical benefits . Ann Intern Med 1975;;83:197-203.
Durbridge TC, Edwards F, Edwards RG, et al:  Evaluation of benefits of screening tests done immediately on admission to hospital . Clin Chem 1976;;22:968-971.
Werner M, Altshuler CH:  Cost effectiveness of multiphasic screening: Old controversies and a new rationale . Hum Pathol 1981;;12:111-117.
Swoyer J, Haus E:  Chronobiology in the clinical laboratory , abstracted. Int J Chronobiol 1981;;7:4.
Bull B, Korpman RA:  Characterization of the WBC differential count . Blood Cells 1980;; 6:411-419.
Wesson SK, Mercado T, Austin M, et al:  Differential counts and overuse of the laboratory . Lancet 1980;;1:552.
Schoen I, Brooks SH:  Judgment based on 95% confidence limits: A statistical dilemma involving multitest screening and proficiency testing of multiple specimens . Am J Clin Pathol 1970;;53:190-193.
Bain BJ, England JM:  Normal haematological values: Sex differences in neutrophil count . Br Med J 1975;;1:306-309.

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Fineberg HV:  Clinical chemistries: The high cost of low cost diagnostic tests , in Altman SH, Blendon R (eds): Medical Technology: The Culprit Behind Health Care Costs? , publication (PHS) 79-3216. US Dept of Health, Education, and Welfare, 1979;, pp 144-165.
Moloney TW, Rogers DE:  Medical technology: A different view of the contentious debate over costs . N Engl J Med 1979;;301:1413-1429.
Canadian Task Force:  The periodic health examination . Can Med Assoc J 1979;;121:1193-1254.
Sackett DL, Holland WW:  Controversy in the detection of disease . Lancet 1975;;2:357-359.
Schneiderman LJ, DeSalvo L, Baylor S, et al:  The abnormal screening laboratory results . Arch Intern Med 1972;;129:88-90.
Korvin CC, Pearce RH, Stanley J:  Admissions screening: Clinical benefits . Ann Intern Med 1975;;83:197-203.
Durbridge TC, Edwards F, Edwards RG, et al:  Evaluation of benefits of screening tests done immediately on admission to hospital . Clin Chem 1976;;22:968-971.
Werner M, Altshuler CH:  Cost effectiveness of multiphasic screening: Old controversies and a new rationale . Hum Pathol 1981;;12:111-117.
Swoyer J, Haus E:  Chronobiology in the clinical laboratory , abstracted. Int J Chronobiol 1981;;7:4.
Bull B, Korpman RA:  Characterization of the WBC differential count . Blood Cells 1980;; 6:411-419.
Wesson SK, Mercado T, Austin M, et al:  Differential counts and overuse of the laboratory . Lancet 1980;;1:552.
Schoen I, Brooks SH:  Judgment based on 95% confidence limits: A statistical dilemma involving multitest screening and proficiency testing of multiple specimens . Am J Clin Pathol 1970;;53:190-193.
Bain BJ, England JM:  Normal haematological values: Sex differences in neutrophil count . Br Med J 1975;;1:306-309.
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