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Bronchogenic Carcinoma With Invasion of the Spine: Title and subTitle BreakTreatment With Combined Surgery and Perioperative Brachytherapy FREE

Dattatreyudu Nori, MD; Naravan Sundaresan, MD; Manjit Bains, MD; Basil S. Hilaris, MD
[+] Author Affiliations

Reprint requests to Department of Radiation Therapy, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021 (Dr Nori).


JAMA. 1982;248(19):2491-2492. doi:10.1001/jama.1982.03330190055032
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A 64-year-old man with bronchogenic carcinoma was noted to have invasion of the chest wall and spine at time of diagnosis. Computed tomography and myelography demonstrated destruction of the vertebral body with epidural extension. After preoperative radiotherapy, resection of the involved lung, chest wall, and spine was accomplished. Afterloading catheters were placed for tumor-bed perioperative iridium 192 irradiation. The patient is free of disease two years after treatment. We describe the afterloading perioperative brachytherapy technique used and suggest this multidisciplinary approach for bronchogenic carcinoma invading the spine.

(JAMA 1982;248:2491-2492)

REFERENCES

McCormack P, Bains MS, Beattie EJ Jr, et al:  New trends in skeletal reconstruction after resection of chest wall tumors . Ann Thorac Surg 1981;;31:45-52.
Grillo JC, Greenberg JJ, Wilkins EW Jr:  Resection of bronchogenic carcinoma involving thoracic wall . J Thorac Cardiovasc Surg 1966;; 51:417-421.
Leonardi HK, Neptune WB:  Surgical management of chest wall tumors . Am J Surg 1980;;139:569-574.
Threlkel JB, Adkins RB Jr:  Primary chest wall tumors . Ann Thorac Surg 1971;;11:450-459.
Parham FW:  Thoracic resection for tumors growing from the bony chest wall . Trans South Surg Assoc 1898;;2:223.
Martini N, Starzynski TE, Beattie EJ Jr:  Problems in chest wall resection . Surg Clin North Am 1969;;49:313-322.
Dunn RC, Jr, Kelly WA, Wohns RN, et al:  Spinal epidural neoplasia: A 15 year review of the results of surgical therapy . J Neurosurg 1980;;52:47-51.
Greenberg HS, Kim JH, Posner JB:  Epidural spinal cord compression from metastatic tumor: Results with a new treatment protocol . Ann Neurol 1980;;8:361-366.
Hilaris BS, Dattatreyudu N, Horowitz BS, et al:  Perioperative brachytherapy in the management of non-oat cell lung cancer , in Hilaris BS, Nori D (eds): Brachytherapy Oncology, 1982: Advances in Lung and Other Cancers . New York, Memorial Sloan-Kettering Cancer Center, 1982;, pp 111-117.
Burnard RJ, Martini N, Beattie EJ Jr:  The value of resection in tumors involving the chest wall . J Thorac Cardiovasc Surg 1974;;68:530-535.
Paulson DL, Shaw RR, Kee JL, et al:  Combined preoperative irradiation and resection for bronchogenic carcinoma . J Thorac Cardiovasc Surg 1962;;44:281-294.
Hilaris BS, Martini N:  Interstitial brachytherapy in cancer of the lung: A 20 year experience . Int J Radiat Oncol Biol Phys 1979;; 5:1951-1956.

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McCormack P, Bains MS, Beattie EJ Jr, et al:  New trends in skeletal reconstruction after resection of chest wall tumors . Ann Thorac Surg 1981;;31:45-52.
Grillo JC, Greenberg JJ, Wilkins EW Jr:  Resection of bronchogenic carcinoma involving thoracic wall . J Thorac Cardiovasc Surg 1966;; 51:417-421.
Leonardi HK, Neptune WB:  Surgical management of chest wall tumors . Am J Surg 1980;;139:569-574.
Threlkel JB, Adkins RB Jr:  Primary chest wall tumors . Ann Thorac Surg 1971;;11:450-459.
Parham FW:  Thoracic resection for tumors growing from the bony chest wall . Trans South Surg Assoc 1898;;2:223.
Martini N, Starzynski TE, Beattie EJ Jr:  Problems in chest wall resection . Surg Clin North Am 1969;;49:313-322.
Dunn RC, Jr, Kelly WA, Wohns RN, et al:  Spinal epidural neoplasia: A 15 year review of the results of surgical therapy . J Neurosurg 1980;;52:47-51.
Greenberg HS, Kim JH, Posner JB:  Epidural spinal cord compression from metastatic tumor: Results with a new treatment protocol . Ann Neurol 1980;;8:361-366.
Hilaris BS, Dattatreyudu N, Horowitz BS, et al:  Perioperative brachytherapy in the management of non-oat cell lung cancer , in Hilaris BS, Nori D (eds): Brachytherapy Oncology, 1982: Advances in Lung and Other Cancers . New York, Memorial Sloan-Kettering Cancer Center, 1982;, pp 111-117.
Burnard RJ, Martini N, Beattie EJ Jr:  The value of resection in tumors involving the chest wall . J Thorac Cardiovasc Surg 1974;;68:530-535.
Paulson DL, Shaw RR, Kee JL, et al:  Combined preoperative irradiation and resection for bronchogenic carcinoma . J Thorac Cardiovasc Surg 1962;;44:281-294.
Hilaris BS, Martini N:  Interstitial brachytherapy in cancer of the lung: A 20 year experience . Int J Radiat Oncol Biol Phys 1979;; 5:1951-1956.
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