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ARTICLE |

The Porphyria, Plumbism, Pottery Puzzle FREE

Thomas D. Bird, MDLt Col ; Donald M. Wallace; Robert F. Labbe, PhD
[+] Author Affiliations

Reprint requests to the Department of Neurology, Veterans Administration Medical Center, 4435 Beacon Ave S, Seattle, WA 98108 (Dr Bird).


JAMA. 1982;247(6):813-814. doi:10.1001/jama.1982.03320310061032
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THE FOLLOWING article describes the solution to a fascinating porphyria, plumbism, pottery puzzle.

Report of a Case  In July 1978, while in California, a 41-year-old woman noted the gradual onset of pain in both knees, spreading to her feet and lower back over a period of weeks. In November, episodic vomiting, decreased appetite, and abdominal cramps developed. These symptoms led to hospitalization in December 1978. Family history was positive for chronic constipation in her father. There was moderate abdominal distention and tenderness without rebound tenderness. Bowel sounds were present, vibratory sensation was decreased in both feet, and ankle reflexes were absent. X-ray films of the abdomen revealed dilated bowel. Upper and lower gastrointestinal tract series revealed normal findings. Spinal fluid protein and glucose levels and cell counts were normal. The patient's hematocrit reading was 31%; hemoglobin level, 10 g/dL; corrected reticulocyte count, 3.7%; mean corpuscular volume, 94 cu μm; mean

REFERENCES

Piepkorn MW, Hamernyik P, Labbe RF:  Modified erythrocyte uroporphyrinogen-I synthase assay and its clinical interpretation . Clin Chem 1978;;24:1751-1754.
Dagg JH, Goldberg A, Lochhead A, et al:  The relationship of lead poisoning to acute intermittent porphyria . Q J Med 1965;;34:163-175.
Meyer UA, Schmid R:  The porphyrias , in Stanbury JB, Wyngaarden JB, Fredrickson DS (eds): The Metabolic Basis of Inherited Disease , ed 4. New York, McGraw-Hill Book Co Inc, 1978;, pp 1166-1220.
Mustajoki P:  Normal erythrocyte uroporphyrinogen I synthase in a kindred with acute intermittent porphyria . Ann Intern Med 1981;; 95:162-166.
Tschudy DP, Valsamis M, Magnussen CR:  Acute intermittent porphyria: Clinical and selected research aspects . Ann Intern Med 1975;; 83:851-864.
Klein M, Namer R, Harpur E, et al:  Earthenware containers as a source of fatal lead poisoning . N Engl J Med 1970;;283:669-672.
Natelson EA, Fred HL:  Lead poisoning from cocktail glasses . JAMA 1976;;236:2527.
Tavolato B, Licandro AC, Argentiero V:  Lead polyneuropathy of nonindustrial origin . Eur Neurol 1980;;19:273-276.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Piepkorn MW, Hamernyik P, Labbe RF:  Modified erythrocyte uroporphyrinogen-I synthase assay and its clinical interpretation . Clin Chem 1978;;24:1751-1754.
Dagg JH, Goldberg A, Lochhead A, et al:  The relationship of lead poisoning to acute intermittent porphyria . Q J Med 1965;;34:163-175.
Meyer UA, Schmid R:  The porphyrias , in Stanbury JB, Wyngaarden JB, Fredrickson DS (eds): The Metabolic Basis of Inherited Disease , ed 4. New York, McGraw-Hill Book Co Inc, 1978;, pp 1166-1220.
Mustajoki P:  Normal erythrocyte uroporphyrinogen I synthase in a kindred with acute intermittent porphyria . Ann Intern Med 1981;; 95:162-166.
Tschudy DP, Valsamis M, Magnussen CR:  Acute intermittent porphyria: Clinical and selected research aspects . Ann Intern Med 1975;; 83:851-864.
Klein M, Namer R, Harpur E, et al:  Earthenware containers as a source of fatal lead poisoning . N Engl J Med 1970;;283:669-672.
Natelson EA, Fred HL:  Lead poisoning from cocktail glasses . JAMA 1976;;236:2527.
Tavolato B, Licandro AC, Argentiero V:  Lead polyneuropathy of nonindustrial origin . Eur Neurol 1980;;19:273-276.
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