0
ARTICLE |

Smoking, Coronary Artery Occlusion, and Nonfatal Myocardial Infarction FREE

Arthur J. Hartz, PhD; Peter N. Barboriak, MS; Alfred J. Anderson, MS; Raymond G. Hoffmann, PhD; Joseph J. Barboriak, ScD
[+] Author Affiliations

Reprint requests to Department of Preventive Medicine, The Medical College of Wisconsin, PO Box 26509, Milwaukee, WI 53226 (Dr Hartz).


JAMA. 1981;246(8):851-853. doi:10.1001/jama.1981.03320080037025
Text Size: A A A
Published online

The association of smoking with a history of myocardial infarction (MI) was studied in 3,997 men who had coronary arteriography. The patients were subdivided into groups based on coronary occlusion (minimal, moderate, or severe) and plasma cholesterol level (low, moderate, or high). For men older than 50 years, smoking was significantly associated with MI in each occlusion group. For men younger than 50 years, the association was significant for men with moderate or severe occlusion. In the presence of higher cholesterol levels there was a stronger association of smoking with MI, but a weaker association of smoking with coronary occlusion. These results suggest that the association of smoking with MI does not depend primarily on the atherogenic effect of smoking. The association seems to be enhanced by high levels of coronary occlusion and cholesterol.

(JAMA 1981;246:851-853)

REFERENCES

Rosenblatt A, Selzer A:  The nature and clinical features of myocardial infarction with normal coronary arteriogram . Circulation 1977;; 55:578-580.
Glyn MF, Mustard JF, Buchanan MR, et al:  Cigarette smoking and platelet aggregation . Can Med Assoc J 1966;;95:549-553.
Anderson AJ, Barboriak JJ, Rimm AA:  Risk factors and angiographically determined coronary occlusion . Am J Epidemiol 1978;;197:8-14.
Rosenberg L, Heqnekens CH, Rosner B, et al:  Oral contraceptive use in relation to nonfatal myocardial infarction . Am J Epidemiol 1980;; 11:59-66.
Rowe GG, Rhomsen JH, Stenlund RR, et al:  A study of hemodynamics and coronary blood flow in men with coronary artery disease . Circulation 1969;;39:139-148.
Block WD, Jarret JK, Levine JB:  Use of a single color reagent to improve the automated determination of serum total cholesterol , in Skeggs LT Jr (ed): Automation in Analytical Chemistry . New York, Mediad, 1965;, pp 345-347.
Aronow WS, Kaplan MA, Jacob D: Tobacco:  A precipitating factor in angina pectoris . Ann Intern Med 1968;;69:529-536.
Aronow WS, Cassidy J, Vangrow JS, et al:  Effect of cigarette smoking and breathing carbon monoxide on cardiovascular hemodynamics in anginal patients . Circulation 1974;;50:340-347.
Doll R, Hull AB:  Mortality in relation to smoking: Ten years observation of British doctors . Br Med J 1964;;1:1399-1410.
Astrup P, Kjeldsen K:  Model studies linking carbon monoxide and/or nicotine to arteriosclerosis and cardiovascular disease . Prev Med 1979;;8:295-302.
Turner DM:  Carbon monoxide, tobacco smoking and the pathogenesis of atherosclerosis . Prev Med 1979;;8:303-309.
Stender S, Astrup P, Kjeldsen K:  The effect of carbon monoxide on cholesterol in the aortic wall of rabbits . Atherosclerosis 1977;; 28:357-367.
Gordon T, Kannel WB, McGee D:  Death and coronary attacks in men after giving up cigarette smoking: A report from the Framingham study . Lancet 1974;;2:1345-1352.
Kannel WB, Doyle JT, McNamara PM, et al:  Precursors of sudden coronary death: Factors related to the incidence of sudden death . Circulation 1976;;51:606-613.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Rosenblatt A, Selzer A:  The nature and clinical features of myocardial infarction with normal coronary arteriogram . Circulation 1977;; 55:578-580.
Glyn MF, Mustard JF, Buchanan MR, et al:  Cigarette smoking and platelet aggregation . Can Med Assoc J 1966;;95:549-553.
Anderson AJ, Barboriak JJ, Rimm AA:  Risk factors and angiographically determined coronary occlusion . Am J Epidemiol 1978;;197:8-14.
Rosenberg L, Heqnekens CH, Rosner B, et al:  Oral contraceptive use in relation to nonfatal myocardial infarction . Am J Epidemiol 1980;; 11:59-66.
Rowe GG, Rhomsen JH, Stenlund RR, et al:  A study of hemodynamics and coronary blood flow in men with coronary artery disease . Circulation 1969;;39:139-148.
Block WD, Jarret JK, Levine JB:  Use of a single color reagent to improve the automated determination of serum total cholesterol , in Skeggs LT Jr (ed): Automation in Analytical Chemistry . New York, Mediad, 1965;, pp 345-347.
Aronow WS, Kaplan MA, Jacob D: Tobacco:  A precipitating factor in angina pectoris . Ann Intern Med 1968;;69:529-536.
Aronow WS, Cassidy J, Vangrow JS, et al:  Effect of cigarette smoking and breathing carbon monoxide on cardiovascular hemodynamics in anginal patients . Circulation 1974;;50:340-347.
Doll R, Hull AB:  Mortality in relation to smoking: Ten years observation of British doctors . Br Med J 1964;;1:1399-1410.
Astrup P, Kjeldsen K:  Model studies linking carbon monoxide and/or nicotine to arteriosclerosis and cardiovascular disease . Prev Med 1979;;8:295-302.
Turner DM:  Carbon monoxide, tobacco smoking and the pathogenesis of atherosclerosis . Prev Med 1979;;8:303-309.
Stender S, Astrup P, Kjeldsen K:  The effect of carbon monoxide on cholesterol in the aortic wall of rabbits . Atherosclerosis 1977;; 28:357-367.
Gordon T, Kannel WB, McGee D:  Death and coronary attacks in men after giving up cigarette smoking: A report from the Framingham study . Lancet 1974;;2:1345-1352.
Kannel WB, Doyle JT, McNamara PM, et al:  Precursors of sudden coronary death: Factors related to the incidence of sudden death . Circulation 1976;;51:606-613.
CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.