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Vestibular Vertigo: Title and subTitle BreakA Form of Polyneuritis? FREE

Kedar K. Adour, MD; Monroe A. Sprague, MD; Raymond L. Hilsinger, Jr, MD
[+] Author Affiliations

Reprint requests to Department of Otolaryngology, Kaiser-Permanente Medical Center, 280 W MacArthur Blvd, Oakland, CA 94611 (Dr Adour).


JAMA. 1981;246(14):1564-1567. doi:10.1001/jama.1981.03320140052030
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Vestibular vertigo traditionally has been considered to be of viral origin and some forms (acute vestibular neuronitis, acute labyrinthitis, acute vertigo) may be manifestations of a viral cranial polyneuritis. To test this hypothesis, otoneurologic signs and serum complement-fixation titers to herpes simplex and herpes zoster were determined in 16 patients with acute vertigo during their attack and several weeks later. One hundred unselected patients seen for nonotoneurologic problems served as control subjects. In addition to vestibular nerve abnormality, all patients with vertigo had some form of cranial nerve abnormality that cleared within four weeks of onset. These transient acute cranial nerve findings in patients with vestibular vertigo support the concept of inflammatory polyneuritis, and preliminary studies indicate that an anti-inflammatory agent such as prednisone may be the preferred treatment.

(JAMA 1981;246:1564-1567)

REFERENCES

Adour KK, Schneider GD, Hilsinger RL Jr:  Acute superior laryngeal nerve palsy: Analysis of 78 cases . Otolaryngol Head Neck Surg 1980;; 88:418-424.
Adour KK, Doty HE:  Electronystagmographic comparison of acute idiopathic and herpes zoster facial paralysis . Laryngoscope 1973;;83:2029-2034.
Nelson JR:  Vertigo , in Beeson PB, McDermott W (eds): Cecil-Loeb Textbook of Medicine , ed 12. Philadelphia, WB Saunders Co, 1967;, pp 1479-1483.
Clemis JD, Becker GW:  Vestibular neuronitis . Otolaryngol Clin North Am 1973;;6:139-155.
Harker LA, McCabe BF:  Meniere's disease and other peripheral labyrinthine disorders , in Paparella MM, Shumrick DA (eds): Otolaryngology . Philadelphia, WB Saunders Co, 1973;, vol 2, pp 439-449.
Coates AC:  Vestibular neuronitis . Acta Otolaryngol Suppl 1969;;251:5-32.
Adour KK, Hilsinger RL Jr, Byl FM:  Herpes simplex polyganglionitis . Otolaryngol Head Neck Surg 1980;;88:270-274.
Nahmias AJ, Roizman B:  Infection with herpes-simplex viruses 1 and 2 (first of three parts) . N Engl J Med 1973;;289:667-674.
Baringer JR, Swoveland P:  Persistent herpes simplex virus infection in rabbit trigeminal ganglia . Lab Invest 1974;;30:230-240.
Stevens JG, Nesburn AB, Cook ML:  Latent herpes simplex virus from trigeminal ganglia of rabbits with recurrent eye infection . Nature 1972;;235:216-217.
Baringer JR, Swoveland P:  Recovery of herpes-simplex virus from human trigeminal ganglions . N Engl J Med 1973;;288:648-650.
Bastian FO, Rabson AS, Yee CL, et al:  Herpesvirus hominis: Isolation from human trigeminal ganglion . Science 1972;;178:306-307.
Warren KG, Brown SM, Wroblewska Z, et al:  Isolation of latent herpes simplex virus from the superior cervical and vagus ganglions of human beings . N Engl J Med 1978;;298:1068-1069.
Adour KK: Bell's palsy:  A complete expression of acute benign cranial polyneuritis . Primary Care 1975;;2:717-733.

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Adour KK, Schneider GD, Hilsinger RL Jr:  Acute superior laryngeal nerve palsy: Analysis of 78 cases . Otolaryngol Head Neck Surg 1980;; 88:418-424.
Adour KK, Doty HE:  Electronystagmographic comparison of acute idiopathic and herpes zoster facial paralysis . Laryngoscope 1973;;83:2029-2034.
Nelson JR:  Vertigo , in Beeson PB, McDermott W (eds): Cecil-Loeb Textbook of Medicine , ed 12. Philadelphia, WB Saunders Co, 1967;, pp 1479-1483.
Clemis JD, Becker GW:  Vestibular neuronitis . Otolaryngol Clin North Am 1973;;6:139-155.
Harker LA, McCabe BF:  Meniere's disease and other peripheral labyrinthine disorders , in Paparella MM, Shumrick DA (eds): Otolaryngology . Philadelphia, WB Saunders Co, 1973;, vol 2, pp 439-449.
Coates AC:  Vestibular neuronitis . Acta Otolaryngol Suppl 1969;;251:5-32.
Adour KK, Hilsinger RL Jr, Byl FM:  Herpes simplex polyganglionitis . Otolaryngol Head Neck Surg 1980;;88:270-274.
Nahmias AJ, Roizman B:  Infection with herpes-simplex viruses 1 and 2 (first of three parts) . N Engl J Med 1973;;289:667-674.
Baringer JR, Swoveland P:  Persistent herpes simplex virus infection in rabbit trigeminal ganglia . Lab Invest 1974;;30:230-240.
Stevens JG, Nesburn AB, Cook ML:  Latent herpes simplex virus from trigeminal ganglia of rabbits with recurrent eye infection . Nature 1972;;235:216-217.
Baringer JR, Swoveland P:  Recovery of herpes-simplex virus from human trigeminal ganglions . N Engl J Med 1973;;288:648-650.
Bastian FO, Rabson AS, Yee CL, et al:  Herpesvirus hominis: Isolation from human trigeminal ganglion . Science 1972;;178:306-307.
Warren KG, Brown SM, Wroblewska Z, et al:  Isolation of latent herpes simplex virus from the superior cervical and vagus ganglions of human beings . N Engl J Med 1978;;298:1068-1069.
Adour KK: Bell's palsy:  A complete expression of acute benign cranial polyneuritis . Primary Care 1975;;2:717-733.
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