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June 5, 1981, Vol 245, No. 21 >
ARTICLE | June 5, 1981

Oncology FREE

Eugene M. McKelvey, MD
[+] Author Affiliations

Member, editorial board, The Journal.


JAMA. 1981;245(21):2209-2211. doi:10.1001/jama.1981.03310460061029
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References

The dramatic therapeutic responses that have been achieved in patients with leukemia, lymphoma, and certain other tumors have led to increased anticipation for the treatment of all patients with malignant disease. While major developments have occurred in different areas of clinical oncology, this past year has been characterized as one of direct clinical application of advances in basic science and technology. In addition, the lessons learned from the treatment of one type of cancer have been incorporated into the management of other forms of malignant neoplasms.

Cancer Detection  The ability to diagnose, stage, and monitor malignant disease accurately is an essential part of the care of patients with cancer. Recent progress in this area has been made with the use of radiolabeled antibodies to specific tumor markers. Historically, the detection and serological quantitation of selected tumor-markers have proved to be of limited clinical value because of lack of specificity and

REFERENCES

1 +
Goldenberg DM, Kim EE, DeLand FH, et al:  Radioimmunodetection of cancer with radioactive antibodies to carcinoembryonic antigen . Cancer Res 1980;;40:2984-2992.
2 +
DeLand FH, Kim EE, Goldenberg DM:  Lymphoscintigraphy with radionuclide-labeled antibodies to carcinoembryonic antigen . Cancer Res 1980;;40:2997-3000.
3 +
Goldenberg DM, Kim EE, DeLand FH, et al:  Clinical studies on the radioimmunodetection of tumors containing α-fetoprotein . Cancer 1980;; 45:2500-2505.
4 +
Ritz J, Pesando JM, Notis-McConarty J, et al:  A monoclonal antibody to human acute lymphoblastic leukaemia antigen . Nature 1980;;283:583-585.
5 +
Kennett RH, Jonak Z, Bechtol KB:  Characterization of antigens with monoclonal antibodies , in Evans AE (ed): Advances in Neuroblastoma Research, vol 12: Progress in Cancer Research and Therapy . New York, Raven Press, 1980;, pp 209-220.
6 +
Brown S, Dilley J, Levy R:  Immunoglobulin secretion by mouse × human hybridomas: An approach for the production of anti-idiotype reagents useful in monitoring patients with B cell lymphoma . J Immunol 1980;;125:1037-1043.
7 +
Lamarque JL, Bruel JM, Dondelinger R, et al:  Computed tomography of metastatic liver: Iodolipid contrast media enhancement in current clinical use . AJR 1979;;133:975-976.
8 +
Tada S, Fukuda K, Aoyagi Y, et al:  CT of abdominal malignancies: Dynamic approach . AJR 1980;;135:455-461.
9 +
Gutterman JU, Blumenschein GR, Alexanian R, et al:  Leukocyte interferon-induced tumor regression in human metastatic breast cancer, multiple myeloma, and malignant lymphoma . Ann Intern Med 1980;; 93:399-406.
10 +
Carter WA, Horoszewicz JS:  Production, purification and clinical application of human fibroblast interferon . Pharmacol Ther 1980;;8:359-377.
11 +
Attallah AM, Petricciani JC, Galasso GJ, et al:  Report of a workshop on standards for human interferon in clinical trials . J Infect Dis 1980;;142:300-301.
12 +
Masucci MG, Szigeti R, Klein E, et al:  Effect of interferon-alpha 1 from E coli on some cell functions . Science 1980;;209:1431-1435.
13 +
Razek A, Perez CA, Tefft M, et al:  Intergroup Ewing's sarcoma study: Local control related to radiation dose, volume, and site of primary lesion in Ewing's sarcoma . Cancer 1980;;46:516-521.
14 +
Maurer HM, Donaldson M, Gehan EA, et al:  Multidisciplinary approach to management of childhood rhabdomyosarcoma , in Proceedings of the National Conference of the Care of the Child With Cancer, Boston, Sept 11-13, 1978 . New York, American Cancer Society, 1979;.
15 +
Rosen G, Caparros B, Nirenberg A, et al:  The successful management of metastatic osteogenic sarcoma: A model for the treatment of primary osteogenic sarcoma , in Van Oosterom AT, Muggia FM (eds): Therapeutic Progress in Ovarian Cancer, Testicular Cancer and the Sarcomas . The Hague, Martinus Nijhoff FB, Boerhaave Series for Postgraduate Medical Education, 1979;, vol 16.
16 +
Legha SS, Buzdar AU, Smith TL, et al:  Complete remissions in metastatic breast cancer treated with combination drug therapy . Ann Intern Med 1979;;91:847-852.
17 +
Legha SS, Keating MJ, Zander AR, et al:  4′(9-acridinylamino) methanesulfon-m-anisidide (AMSA): A new drug effective in the treatment of adult leukemia . Ann Intern Med 1980;;93:17-21.
18 +
Valdivieso M, Moore CE, Burgess AM, et al:  Phase I clinical study of N-(phosphonacetyl)-L-aspartic acid (PALA) . Cancer Treat Rep 1980;; 64:285-292.
19 +
Bedikian AY, Valdivieso M, Maroun J, et al:  Evaluation of vindesine and MER in colorectal cancer . Cancer 1980;;46:463-467.

Figures

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Goldenberg DM, Kim EE, DeLand FH, et al:  Radioimmunodetection of cancer with radioactive antibodies to carcinoembryonic antigen . Cancer Res 1980;;40:2984-2992.
2 +
DeLand FH, Kim EE, Goldenberg DM:  Lymphoscintigraphy with radionuclide-labeled antibodies to carcinoembryonic antigen . Cancer Res 1980;;40:2997-3000.
3 +
Goldenberg DM, Kim EE, DeLand FH, et al:  Clinical studies on the radioimmunodetection of tumors containing α-fetoprotein . Cancer 1980;; 45:2500-2505.
4 +
Ritz J, Pesando JM, Notis-McConarty J, et al:  A monoclonal antibody to human acute lymphoblastic leukaemia antigen . Nature 1980;;283:583-585.
5 +
Kennett RH, Jonak Z, Bechtol KB:  Characterization of antigens with monoclonal antibodies , in Evans AE (ed): Advances in Neuroblastoma Research, vol 12: Progress in Cancer Research and Therapy . New York, Raven Press, 1980;, pp 209-220.
6 +
Brown S, Dilley J, Levy R:  Immunoglobulin secretion by mouse × human hybridomas: An approach for the production of anti-idiotype reagents useful in monitoring patients with B cell lymphoma . J Immunol 1980;;125:1037-1043.
7 +
Lamarque JL, Bruel JM, Dondelinger R, et al:  Computed tomography of metastatic liver: Iodolipid contrast media enhancement in current clinical use . AJR 1979;;133:975-976.
8 +
Tada S, Fukuda K, Aoyagi Y, et al:  CT of abdominal malignancies: Dynamic approach . AJR 1980;;135:455-461.
9 +
Gutterman JU, Blumenschein GR, Alexanian R, et al:  Leukocyte interferon-induced tumor regression in human metastatic breast cancer, multiple myeloma, and malignant lymphoma . Ann Intern Med 1980;; 93:399-406.
10 +
Carter WA, Horoszewicz JS:  Production, purification and clinical application of human fibroblast interferon . Pharmacol Ther 1980;;8:359-377.
11 +
Attallah AM, Petricciani JC, Galasso GJ, et al:  Report of a workshop on standards for human interferon in clinical trials . J Infect Dis 1980;;142:300-301.
12 +
Masucci MG, Szigeti R, Klein E, et al:  Effect of interferon-alpha 1 from E coli on some cell functions . Science 1980;;209:1431-1435.
13 +
Razek A, Perez CA, Tefft M, et al:  Intergroup Ewing's sarcoma study: Local control related to radiation dose, volume, and site of primary lesion in Ewing's sarcoma . Cancer 1980;;46:516-521.
14 +
Maurer HM, Donaldson M, Gehan EA, et al:  Multidisciplinary approach to management of childhood rhabdomyosarcoma , in Proceedings of the National Conference of the Care of the Child With Cancer, Boston, Sept 11-13, 1978 . New York, American Cancer Society, 1979;.
15 +
Rosen G, Caparros B, Nirenberg A, et al:  The successful management of metastatic osteogenic sarcoma: A model for the treatment of primary osteogenic sarcoma , in Van Oosterom AT, Muggia FM (eds): Therapeutic Progress in Ovarian Cancer, Testicular Cancer and the Sarcomas . The Hague, Martinus Nijhoff FB, Boerhaave Series for Postgraduate Medical Education, 1979;, vol 16.
16 +
Legha SS, Buzdar AU, Smith TL, et al:  Complete remissions in metastatic breast cancer treated with combination drug therapy . Ann Intern Med 1979;;91:847-852.
17 +
Legha SS, Keating MJ, Zander AR, et al:  4′(9-acridinylamino) methanesulfon-m-anisidide (AMSA): A new drug effective in the treatment of adult leukemia . Ann Intern Med 1980;;93:17-21.
18 +
Valdivieso M, Moore CE, Burgess AM, et al:  Phase I clinical study of N-(phosphonacetyl)-L-aspartic acid (PALA) . Cancer Treat Rep 1980;; 64:285-292.
19 +
Bedikian AY, Valdivieso M, Maroun J, et al:  Evaluation of vindesine and MER in colorectal cancer . Cancer 1980;;46:463-467.

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