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December 19, 1980, Vol 244, No. 24 >
ARTICLE | December 19, 1980

Management of Pregnancy in Women With Immune Thrombocytopenic Purpura FREE

Harry W. Carloss, MD; Robert McMillan, MD; William H. Crosby, MD
[+] Author Affiliations

Reprint requests to Division of Hematology-Oncology, Scripps Clinic and Research Foundation, 10666 N Torrey Pines Rd, La Jolla, CA 92037 (Dr Carloss).


JAMA. 1980;244(24):2756-2758. doi:10.1001/jama.1980.03310240048027
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References

Immune thrombocytopenic purpura (ITP) may develop during pregnancy or affect later pregnancies. When this occurs, the obstetrician usually seeks the internist for help. The mother and fetus are at serious risk from thrombocytopenia and the measures that can control it. Case reports published since 1950 examine the pathogenesis of ITP and its special problems during pregnancy. Recommendations for management derive from these problems.

(JAMA 1980;244:2756-2758)

REFERENCES

1 +
McMillan R:  The pathogenesis of immune thrombocytopenic purpura . CRC Crit Rev Clin Lab Sci 1977;;8:303-332.
2 +
Dixon R, Rosse W, Ebbert L:  Quantitative determination of antibody in idiopathic thrombocytopenic purpura . N Engl J Med 1975;;292:230-236.
3 +
Kitzmiller JL:  Autoimmune disorders: Maternal, fetal, and neonatal risks . Clin Obstet Gynecol 1978;;21:385-396.
4 +
Heys R:  Steroid therapy for idiopathic thrombocytopenic purpura during pregnancy . Obstet Gynecol 1966;;28:532-542.
5 +
Peterson O, Larson P:  Thrombocytopenic purpura in pregnancy . Obstet Gynecol 1954;; 4:454-469.
6 +
Pearson HA, McIntosh S:  Neonatal thrombocytopenia . Clin Haematol 1978;;7:111-122.
7 +
Kelemen E, Szalay F, Petefy M:  Autoimmune (idiopathic) thrombocytopenic purpura in pregnancy and the newborn . Br J Obstet Gynaecol 1978;;85:239.
8 +
Nelson W, Vaughan V, McKay R, et al: Textbook of Pediatrics , ed 11. Philadelphia, WB Saunders Co, 1979;, pp 1416-1418.
9 +
Jones R, Asher M, Rutheford C, et al:  Autoimmune (idiopathic) thrombocytopenic purpura in pregnancy and the newborn . Br J Obstet Gynaecol 1977;;84:679-683.
10 +
Territo M, Finklestein J, Oh O, et al:  Management of autoimmune thrombocytopenia in pregnancy and the neonatal . Obstet Gynecol 1973;;41:579-582.
11 +
Robson H, Davidson L:  Purpura in pregnancy . Lancet 1950;;2:164-169.
12 +
Mennuti M, Schwarz R, Gill F:  Obstetric management of isoimmune thrombocytopenia . Am J Obstet Gynecol 1974;;118:565-566.
13 +
Anguilo J, Temple J, Corrigan J, et al:  Management of cesarean section in a patient with idiopathic thrombocytopenic purpura . Anesthesiology 1977;;46:145-147.
14 +
Gowda V, Apuzzio J, Langer A, et al:  Pregnancy complicated by refractory idiopathic thrombocytopenic purpura and diabetes mellitus . J Reprod Med 1977;;19:145-150.
15 +
Murray J, Harris R:  The management of the pregnant patient with idiopathic thrombocytopenic purpura . Am J Obstet Gynecol 1976;; 126:449-451.
16 +
Mendel E, Sparkman R:  Idiopathic thrombocytopenic purpura in pregnancy . Obstet Gynecol Surv 1957;;28:156-170.
17 +
Goodhue P, Evans T:  Idiopathic thrombocytopenic purpura in pregnancy . Obstet Gynecol Surv 1962;;18:671-693.
18 +
O'Reilly R, Taber B:  Immunologic thrombocytopenic purpura and pregnancy . Obstet Gynecol 1978;;51:590-597.
19 +
Bottoms S, Rosen M, Sokol R:  The increase in cesarean birth rate . N Engl J Med 1980;; 302:559-563.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
McMillan R:  The pathogenesis of immune thrombocytopenic purpura . CRC Crit Rev Clin Lab Sci 1977;;8:303-332.
2 +
Dixon R, Rosse W, Ebbert L:  Quantitative determination of antibody in idiopathic thrombocytopenic purpura . N Engl J Med 1975;;292:230-236.
3 +
Kitzmiller JL:  Autoimmune disorders: Maternal, fetal, and neonatal risks . Clin Obstet Gynecol 1978;;21:385-396.
4 +
Heys R:  Steroid therapy for idiopathic thrombocytopenic purpura during pregnancy . Obstet Gynecol 1966;;28:532-542.
5 +
Peterson O, Larson P:  Thrombocytopenic purpura in pregnancy . Obstet Gynecol 1954;; 4:454-469.
6 +
Pearson HA, McIntosh S:  Neonatal thrombocytopenia . Clin Haematol 1978;;7:111-122.
7 +
Kelemen E, Szalay F, Petefy M:  Autoimmune (idiopathic) thrombocytopenic purpura in pregnancy and the newborn . Br J Obstet Gynaecol 1978;;85:239.
8 +
Nelson W, Vaughan V, McKay R, et al: Textbook of Pediatrics , ed 11. Philadelphia, WB Saunders Co, 1979;, pp 1416-1418.
9 +
Jones R, Asher M, Rutheford C, et al:  Autoimmune (idiopathic) thrombocytopenic purpura in pregnancy and the newborn . Br J Obstet Gynaecol 1977;;84:679-683.
10 +
Territo M, Finklestein J, Oh O, et al:  Management of autoimmune thrombocytopenia in pregnancy and the neonatal . Obstet Gynecol 1973;;41:579-582.
11 +
Robson H, Davidson L:  Purpura in pregnancy . Lancet 1950;;2:164-169.
12 +
Mennuti M, Schwarz R, Gill F:  Obstetric management of isoimmune thrombocytopenia . Am J Obstet Gynecol 1974;;118:565-566.
13 +
Anguilo J, Temple J, Corrigan J, et al:  Management of cesarean section in a patient with idiopathic thrombocytopenic purpura . Anesthesiology 1977;;46:145-147.
14 +
Gowda V, Apuzzio J, Langer A, et al:  Pregnancy complicated by refractory idiopathic thrombocytopenic purpura and diabetes mellitus . J Reprod Med 1977;;19:145-150.
15 +
Murray J, Harris R:  The management of the pregnant patient with idiopathic thrombocytopenic purpura . Am J Obstet Gynecol 1976;; 126:449-451.
16 +
Mendel E, Sparkman R:  Idiopathic thrombocytopenic purpura in pregnancy . Obstet Gynecol Surv 1957;;28:156-170.
17 +
Goodhue P, Evans T:  Idiopathic thrombocytopenic purpura in pregnancy . Obstet Gynecol Surv 1962;;18:671-693.
18 +
O'Reilly R, Taber B:  Immunologic thrombocytopenic purpura and pregnancy . Obstet Gynecol 1978;;51:590-597.
19 +
Bottoms S, Rosen M, Sokol R:  The increase in cesarean birth rate . N Engl J Med 1980;; 302:559-563.

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