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ARTICLE |

The Role of the Physician in Occupational Epidemics FREE

Peter James Dyck, MD
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Address editorial communications to the Editor, 535 N Dearborn St, Chicago, IL 60610.


JAMA. 1980;243(8):771-771. doi:10.1001/jama.1980.03300340047022
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Two epidemics of neuropathy, initially seen as urinary retention and impotence, described in this issue of The Journal by Keogh and co-workers (p 746) and by Kreiss and co-workers (p 741) and linked by them to exposure to an industrial toxin, are unusual and instructive.

Several recent epidemics of neuropathy come to mind, but none like the present one. Only a few years ago, the swine influenza immunization program in the United States was found to be associated with an increased frequency of a paralytic disorder, Guillain-Barré syndrome.1 Before that, a group of workers experienced a sensory ataxic neuropathy from formulating an ant pesticide, chlordecone.2 Methyl-n-butyl ketone exposure in several Ohio plants produced a serious outbreak of a sensory motor neuropathy.3 Worldwide, a serious outbreak of diffuse neuropathy in Japan resulted from eating fish taken from Minimata Bay heavily contaminated with methyl mercury.4 In

REFERENCES

Nelson DB, Holman R, Hurwitz E, et al:  Results of the national surveillance for Guillain-Barré syndrome . Neurology 29:1029-1032, 1979;.
Martinez AJ, Taylor JR, Dyck PJ, et al:  Chlordecone intoxication in man: II. Ultrastructure of peripheral nerves and skeletal muscle . Neurology 28:631-635, 1978;.
Allen N, Mendell JR, Billmaier DJ, et al:  Toxic polyneuropathy due to methyl n-butyl ketone . Arch Neurol 32:209-222, 1975;.
Takeuchi T, Morikawa N, Matsumoto H, et al:  A pathological study of Minimata disease in Japan . Acta Neuropathol (Berl) 2:40-57, 1962;.
Smith HV, Spalding JMK:  Outbreak of paralysis in Morocco due to orthocresyl phosphate poisoning . Lancet 2:1019-1021, 1959;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Nelson DB, Holman R, Hurwitz E, et al:  Results of the national surveillance for Guillain-Barré syndrome . Neurology 29:1029-1032, 1979;.
Martinez AJ, Taylor JR, Dyck PJ, et al:  Chlordecone intoxication in man: II. Ultrastructure of peripheral nerves and skeletal muscle . Neurology 28:631-635, 1978;.
Allen N, Mendell JR, Billmaier DJ, et al:  Toxic polyneuropathy due to methyl n-butyl ketone . Arch Neurol 32:209-222, 1975;.
Takeuchi T, Morikawa N, Matsumoto H, et al:  A pathological study of Minimata disease in Japan . Acta Neuropathol (Berl) 2:40-57, 1962;.
Smith HV, Spalding JMK:  Outbreak of paralysis in Morocco due to orthocresyl phosphate poisoning . Lancet 2:1019-1021, 1959;.
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