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January 11, 1980, Vol 243, No. 2 >
ARTICLE | January 11, 1980

Herpes Simplex Infection at Term: Title and subTitle BreakWhat to Do With Mother, Newborn, and Nursery Personnel FREE

Sidney Kibrick, MD, PhD
[+] Author Affiliations

Reprint requests to Department of Pediatrics, Boston University Medical Center, 80 E Concord St, Boston, MA 02118 (Dr Kibrick).


JAMA. 1980;243(2):157-160. doi:10.1001/jama.1980.03300280051033
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References

LITTLE has been published regarding infection control procedures for the woman with an active herpetic infection at term, or for her newborn infant. As yet, no authoritative body has addressed itself to these points in generally available journals. There is also no current agreement on the criteria for cesarean section in the woman with genital herpes infection at term and no uniform policy for managing nursery personnel with herpetic lesions on exposed body surfaces. That guidelines are needed is apparent from numerous requests to our unit for advice on dealing with such problems.

In this article, the risks to the newborn arising from herpetic infection in the mother at term are considered and the possible role of cesarean section in minimizing these risks is reviewed. Based on these data, recommendations for treating such mothers are made. In addition, we suggest infection control procedures for the mothers, their newborns, and for

REFERENCES

1 +
Nahmias AJ, Alford CA, Korones SB:  Infection of the newborn with herpesvirus hominis. . Adv Pediatr 17:185-226, 1970;.
2 +
Nahmias AJ, Josey WE, ZM, et al:  Perinatal risk associated with maternal genital herpes simplex virus infection . Am J Obstet loceny G 110:825-834, 1971;.
3 +
Hanshaw JB:  Herpesvirus hominis tions in the fetus and the newborn . Am J Dis Child 126:546-555, 1973;.
4 +
Nahmias AJ, Josey WE, Naib ZM:  Significance of herpes simplex virus infection during pregnancy . Clin Obstet Gynecol 15:929-938, 1972;.
5 +
Amstey MS:  Management of pregnancy complicated by genital herpes virus infection . Obstet Gynecol 37:515-520, 1971;.
6 +
Light IJ, Linnemann CC Jr:  Neonatal herpes simplex infection following delivery by cesarean section . Obstet Gynecol 44:496-499, 1974;.
7 +
Adams HG, Benson EA, Alexander ER, et al:  Genital herpetic infection in men and women: Clinical course and effect of topical application of adenine arabinoside . J Infect Dis 133( (suppl A) ):151-159, 1976;.
8 +
Yen SSC, Reagan JW, Rosenthal MS:  Herpes simplex infection in female genital tract . Obstet Gynecol 25:479-492, 1965;.
9 +
Kaufman RH, Gardner HL, Rawls WE, et al:  Clinical features of herpes genitalis . Cancer Res 33:1446-1448, 1973;.
10 +
Ng ABP, Reagan JW, Yen SSC:  Herpes genitalis: Clinical and cytopathologic experience with 256 patients . Obstet Gynecol 36:645-651, 1970;.
11 +
Nahmias AJ, Visintine AM, Josey WE:  Cesarean section and genital herpes . N Engl J Med 296:1359, 1977;.
12 +
Chang T-W, O'Keefe P:  Cesarean section and genital herpes . N Engl J Med 296:573, 1977;.
13 +
Visintine AM, Nahmias AJ, Josey WE:  Genital herpes . Perinatal Care 2:32-41, 1978;.
14 +
Naib ZM, Nahmias AJ, Josey WE, et al:  Relation of cytohistopathology of genital herpesvirus infection to cervical anaplasia . Cancer Res 33:1452-1458, 1973;.
15 +
Asculai SS, Weis MT, Rancourt MW, et al:  Inactivation of herpes simplex viruses by nonionic surfactants . Antimicrob Agents Chemother 13:686-690, 1978;.
16 +
Hayes K, Danks DM, Gibas H, et al:  Cytomegalovirus in human milk . N Engl J Med 287:177-178, 1972;.
17 +
Reynolds DW, Stagno S, Hosty TS, et al:  Maternal cytomegalovirus excretion and perinatal infection . N Engl J Med 289:1-5, 1973;.
18 +
Francis DP, Hermann KL, MacMahon JR, et al:  Nosocomial and maternally acquired herpesvirus hominis infections: A report of four fatal cases in neonates . Am J Dis Child 129:889-893, 1975;.
19 +
Isolation Techniques for Use in Hospitals, ed 2. HEW publication no. (CDC) 78-8314, Washington, DC, US Government Printing Office, 1975.
20 +
Schreiner RL, Kleinman MB, Gresham EL:  Maternal oral herpes: Isolation policy . Pediatrics 63:247-249, 1979;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Nahmias AJ, Alford CA, Korones SB:  Infection of the newborn with herpesvirus hominis. . Adv Pediatr 17:185-226, 1970;.
2 +
Nahmias AJ, Josey WE, ZM, et al:  Perinatal risk associated with maternal genital herpes simplex virus infection . Am J Obstet loceny G 110:825-834, 1971;.
3 +
Hanshaw JB:  Herpesvirus hominis tions in the fetus and the newborn . Am J Dis Child 126:546-555, 1973;.
4 +
Nahmias AJ, Josey WE, Naib ZM:  Significance of herpes simplex virus infection during pregnancy . Clin Obstet Gynecol 15:929-938, 1972;.
5 +
Amstey MS:  Management of pregnancy complicated by genital herpes virus infection . Obstet Gynecol 37:515-520, 1971;.
6 +
Light IJ, Linnemann CC Jr:  Neonatal herpes simplex infection following delivery by cesarean section . Obstet Gynecol 44:496-499, 1974;.
7 +
Adams HG, Benson EA, Alexander ER, et al:  Genital herpetic infection in men and women: Clinical course and effect of topical application of adenine arabinoside . J Infect Dis 133( (suppl A) ):151-159, 1976;.
8 +
Yen SSC, Reagan JW, Rosenthal MS:  Herpes simplex infection in female genital tract . Obstet Gynecol 25:479-492, 1965;.
9 +
Kaufman RH, Gardner HL, Rawls WE, et al:  Clinical features of herpes genitalis . Cancer Res 33:1446-1448, 1973;.
10 +
Ng ABP, Reagan JW, Yen SSC:  Herpes genitalis: Clinical and cytopathologic experience with 256 patients . Obstet Gynecol 36:645-651, 1970;.
11 +
Nahmias AJ, Visintine AM, Josey WE:  Cesarean section and genital herpes . N Engl J Med 296:1359, 1977;.
12 +
Chang T-W, O'Keefe P:  Cesarean section and genital herpes . N Engl J Med 296:573, 1977;.
13 +
Visintine AM, Nahmias AJ, Josey WE:  Genital herpes . Perinatal Care 2:32-41, 1978;.
14 +
Naib ZM, Nahmias AJ, Josey WE, et al:  Relation of cytohistopathology of genital herpesvirus infection to cervical anaplasia . Cancer Res 33:1452-1458, 1973;.
15 +
Asculai SS, Weis MT, Rancourt MW, et al:  Inactivation of herpes simplex viruses by nonionic surfactants . Antimicrob Agents Chemother 13:686-690, 1978;.
16 +
Hayes K, Danks DM, Gibas H, et al:  Cytomegalovirus in human milk . N Engl J Med 287:177-178, 1972;.
17 +
Reynolds DW, Stagno S, Hosty TS, et al:  Maternal cytomegalovirus excretion and perinatal infection . N Engl J Med 289:1-5, 1973;.
18 +
Francis DP, Hermann KL, MacMahon JR, et al:  Nosocomial and maternally acquired herpesvirus hominis infections: A report of four fatal cases in neonates . Am J Dis Child 129:889-893, 1975;.
19 +
Isolation Techniques for Use in Hospitals, ed 2. HEW publication no. (CDC) 78-8314, Washington, DC, US Government Printing Office, 1975.
20 +
Schreiner RL, Kleinman MB, Gresham EL:  Maternal oral herpes: Isolation policy . Pediatrics 63:247-249, 1979;.

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