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The Dog Heartworm (Dirofilaria immitis) in Man: Title and subTitle BreakAn Epidemic Pending or in Progress? FREE

Jonathan R. Merrill, MD; John Otis, MD; William D. Logan, Jr, MD; M. Bedford Davis, MD
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JAMA. 1980;243(10):1066-1068. doi:10.1001/jama.1980.03300360038023
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Human infection with the dog heartworm (Dirofilaria immitis) may lead to focal pulmonary infarction with granuloma formation. The resulting roentgenographic coin lesion may require a diagnostic thoracotomy in consideration of malignancy. Because of sometimes enigmatic histopathological characteristics, this process may not be receiving the recognition it deserves. Furthermore, the dramatic increase of primary (canine) host infections in the United States presages an increase of secondary (human) host infections. Many thoracotomies will be performed for this innocuous process unless the dirofilarial agent can be controlled or the human pulmonary lesion can be reliably identified without operation.

(JAMA 243:1066-1068, 1980)

REFERENCES

Dashiell GF:  A case of dirofilariasis involving the lung . Am J Trop Med 10:37-39, 1961;.
Robinson NB, Chavez CM, Conn JH:  Pulmonary dirofilariasis in man: A case report and review of the literature . J Thorac Cardiovasc Surg 74:403-408, 1977;.
Riskin W, Toppell KL:  Pulmonary dirofilariasis: Another coin lesion . South Med J 70:502-503, 1977;.
Prioleau WH, Parker EF, Bradham RR, et al:  Dirofilaria immitis (dog heartworm) as a pulmonary lesion in humans . Ann Thorac Surg 21:382-385, 1976;.
Leonardi HK, Lapey JD, Ellis FH:  Pulmonary dirofilariasis: A report of a human case . Thorax 32:612-615, 1977;.
 Case 13-1979, Case records of the Massachusetts General Hospital . N Engl J Med 300:723-729, 1979;.
Dayal Y, Neafie RC:  Human pulmonary dirofilariasis: A case report and review of the literature . Am Rev Respir Dis 112:437-443, 1975;.
Otto GF, Morgan HC, Jackson RF, et al: Proceedingsof the Heartworm Symposium '77 . Bonner Springs, Kan, Veterinary Medicine Publishing Co, 1978;.

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Dashiell GF:  A case of dirofilariasis involving the lung . Am J Trop Med 10:37-39, 1961;.
Robinson NB, Chavez CM, Conn JH:  Pulmonary dirofilariasis in man: A case report and review of the literature . J Thorac Cardiovasc Surg 74:403-408, 1977;.
Riskin W, Toppell KL:  Pulmonary dirofilariasis: Another coin lesion . South Med J 70:502-503, 1977;.
Prioleau WH, Parker EF, Bradham RR, et al:  Dirofilaria immitis (dog heartworm) as a pulmonary lesion in humans . Ann Thorac Surg 21:382-385, 1976;.
Leonardi HK, Lapey JD, Ellis FH:  Pulmonary dirofilariasis: A report of a human case . Thorax 32:612-615, 1977;.
 Case 13-1979, Case records of the Massachusetts General Hospital . N Engl J Med 300:723-729, 1979;.
Dayal Y, Neafie RC:  Human pulmonary dirofilariasis: A case report and review of the literature . Am Rev Respir Dis 112:437-443, 1975;.
Otto GF, Morgan HC, Jackson RF, et al: Proceedingsof the Heartworm Symposium '77 . Bonner Springs, Kan, Veterinary Medicine Publishing Co, 1978;.
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