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ARTICLE |

Less Hazardous Cigarette Debated FREE

G. H. Miller, PhD; John Schumaker, PhD
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Edited by John D. Archer, MD, Senior Editor.


JAMA. 1979;242(10):1029-1029. doi:10.1001/jama.1979.03300100011003
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To the Editor.—  The article "Toward Less Hazardous Cigarettes: Current Advances" by Gori and Lynch (240:1255, 1978) in The Journal appears to have a number of serious deficiencies. An analysis of the data and the references cited in the article shows the following discrepancies:

  1. The basis for the computation of the "tolerable levels" of cigarettes that "would not significantly increase the risk to the smoker when compared to the nonsmoker" does not appear to be valid. In the initial article by Gori,1 "Low-Risk Cigarettes: A Prescription," published in Science in 1976, the author develops the concept of "critical value," which is the basis for the computations on the tolerable levels of cigarettes. However, his computations of the critical values are based on assumptions that are not documented. These computations are not valid representations of the data analyzed. His assumptions for critical values have been criticized by a number of

REFERENCES

Gori GB:  Low-risk cigarettes: A prescription . Science 194:1243-1246, 1976;.
Marx JL:  Health officials fired up over "tolerable" cigarettes . Science 201:795-798, 1978;.
Astrup P:  Studies on carbon monoxide and nicotine , in Smoking & Health. Modifying the Risk for the Smoker , vol 1. US Dept of Health, Education, and Welfare publication No. NIH 76-1221, 1976;, pp 331-341.
Astrup P:  Some physiological and pathological effects of moderate carbon monoxide exposure . Br Med J 4:447-452, 1972;.
Wald J:  Mortality from lung cancer and coronary heart-disease in relation to changes in smoking habits . Lancet 1:136-138, 1976;.

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Gori GB:  Low-risk cigarettes: A prescription . Science 194:1243-1246, 1976;.
Marx JL:  Health officials fired up over "tolerable" cigarettes . Science 201:795-798, 1978;.
Astrup P:  Studies on carbon monoxide and nicotine , in Smoking & Health. Modifying the Risk for the Smoker , vol 1. US Dept of Health, Education, and Welfare publication No. NIH 76-1221, 1976;, pp 331-341.
Astrup P:  Some physiological and pathological effects of moderate carbon monoxide exposure . Br Med J 4:447-452, 1972;.
Wald J:  Mortality from lung cancer and coronary heart-disease in relation to changes in smoking habits . Lancet 1:136-138, 1976;.
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