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ARTICLE |

Cervical Osteomyelitis FREE

John A. D'Elia, MD; Ramachandiran Cooppan, MD; Donna Younger, MD; S. Schoenbaum, MD; S. Freidberg, MD
JAMA. 1979;241(1):29-29. doi:10.1001/jama.1979.03290270021011
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To the Editor.—  Drs Parker and Tuazon have succinctly described two patients with vertebral osteomyelitis acquired in association with chronic hemodialysis (240:50, 1978). Other reports have suggested urinary tract disease,1 intravenous drug abuse,2 and indwelling intravenous catheters3 as the route of entry.In a review of our experience with vertebral osteomyelitis among insulin-dependent diabetics,4 we uncovered only one with chronic bacteriuria and one with prior osteomyelitis as potential portals of entry. Subsequently, we have observed vertebral osteomyelitis in an immunosuppressed patient following successful renal transplantation at a time when glucocorticoid-induced diabetes had developed. We have not found vertebral osteomyelitis in our dialysis patients.Thus, we would emphasize the importance of underlying systemic disease in predisposition to vertebral osteomyelitis, as well as the probability of an increased incidence with the use of immunosuppressive drugs. The absence of an obvious portal of entry reinforces the concept of a diagnostic

REFERENCES

Bruno MS, Silverbert TN, Goldstein OH:  Embolic osteomyelitis of the spine as a complication of infection of the urinary tract . Am J Med 42:865-877, 1960;.
Holzman RS, Bishdo F:  Osteomyelitis in heroin addicts . Ann Intern Med 75:693-696, 1971;.
Edwards JE, Turkel SB, Eloer HA:  Hematogenous Candida osteomyelitis . Am J Med 59:89-94, 1975;.
Cooppan R, Schoenbaum S, Younger MD:  Vertebral osteomyelitis in insulin-dependeht diabetics . S Afr Med J 50:1993-1996, 1976;.
Musher DM, Thorsteinsson SB, Minuth JN:  Vertebral osteomyelitis still a diagnostic pitfall . Arch Intern Med 136:105-110, 1976;.

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Bruno MS, Silverbert TN, Goldstein OH:  Embolic osteomyelitis of the spine as a complication of infection of the urinary tract . Am J Med 42:865-877, 1960;.
Holzman RS, Bishdo F:  Osteomyelitis in heroin addicts . Ann Intern Med 75:693-696, 1971;.
Edwards JE, Turkel SB, Eloer HA:  Hematogenous Candida osteomyelitis . Am J Med 59:89-94, 1975;.
Cooppan R, Schoenbaum S, Younger MD:  Vertebral osteomyelitis in insulin-dependeht diabetics . S Afr Med J 50:1993-1996, 1976;.
Musher DM, Thorsteinsson SB, Minuth JN:  Vertebral osteomyelitis still a diagnostic pitfall . Arch Intern Med 136:105-110, 1976;.
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