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ARTICLE |

Purulent Rectal Discharge Associated With a Nontreponemal Spirochete FREE

Lawrence R. Kaplan, MD; Akio Takeuchi, MD
[+] Author Affiliations

Reprint requests to Division of Gastroenterology, Box 36 Mayo, University of Minnesota, Minneapolis, MN 55455 (Dr Kaplan).


JAMA. 1979;241(1):52-53. doi:10.1001/jama.1979.03290270042018
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A nontreponemal spirochete was isolated from the rectum of a homosexual man with a chronic purulent discharge. Known infectious causes of the disease were excluded. Although the pathogenicity of the organism was not proved, the patient's symptoms rapidly resolved following penicillin G benzathine therapy. When culture of a nonhemorrhagic, purulent rectal discharge fails to verify Neisseria gonorrhoeae, health care personnel are encouraged to carefully examine a Gram's-stained smear of the discharge for spiral-shaped organisms.

(JAMA 241:52-53, 1979)

REFERENCES

Fantham HB:  Observations of Spirochaeta eurygyrata as found in human feces . Br Med J 1:815-816, 1916;.
Macfie SW:  The prevalence of Spirochaeta eurygyrata in Europeans and natives in the Gold Coast . Lancet 1:336-340, 1917;.
Parr LW:  Intestinal spirochaetes . J Infect Dis 33:369-383, 1923;.
Lee FD, Kraszewski A, Gordon J, et al:  Intestinal spirochaetosis . Gut 12:126-133, 1971;.
Takeuchi A, Jervis HR, Nakazawa H, et al:  Spiral-shaped organisms on the surface colonic epithelium of the monkey and man . Am J Clin Nutr 27:1287-1296, 1974;.
Takeuchi A, Zeller JA:  Ultrastructural identification of spirochetes and flagellated microbes at the brush border of the large intestinal epithelium of the rhesus monkey . Infect Immun 6:1008-1018, 1972;.
Gear EV, Dobbins WO:  Rectal biopsy . Gastroenterology 55:522-541, 1968;.

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Fantham HB:  Observations of Spirochaeta eurygyrata as found in human feces . Br Med J 1:815-816, 1916;.
Macfie SW:  The prevalence of Spirochaeta eurygyrata in Europeans and natives in the Gold Coast . Lancet 1:336-340, 1917;.
Parr LW:  Intestinal spirochaetes . J Infect Dis 33:369-383, 1923;.
Lee FD, Kraszewski A, Gordon J, et al:  Intestinal spirochaetosis . Gut 12:126-133, 1971;.
Takeuchi A, Jervis HR, Nakazawa H, et al:  Spiral-shaped organisms on the surface colonic epithelium of the monkey and man . Am J Clin Nutr 27:1287-1296, 1974;.
Takeuchi A, Zeller JA:  Ultrastructural identification of spirochetes and flagellated microbes at the brush border of the large intestinal epithelium of the rhesus monkey . Infect Immun 6:1008-1018, 1972;.
Gear EV, Dobbins WO:  Rectal biopsy . Gastroenterology 55:522-541, 1968;.
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