Cooperative Study of Hospital Frequency and Character of Transient Ischemic Attacks: Title and subTitle BreakVIII. Risk Factors FREE

P. Michael Conneally, PhD; Mark L. Dyken, MD; Dennis E. Futty, MS; David C. Poskanzer, MD; Philip R. Calanchini, MD; Phillip D. Swanson, MD; Thomas R. Price, MD; Armin F. Haerer, MD; Robert A. Gotshall, MD

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For university affiliations and additional contributors, see Table 1.

Reprint requests to Indiana University School of Medicine, Department of Neurology, 1100 W Michigan St, Indianapolis, IN 46202 (Dr Dyken).

JAMA. 1978;240(8):742-746. doi:10.1001/jama.1978.03290080032019

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ABSTRACT

ABSTRACT | REFERENCES

A total of 969 (73%) of 1,328 patients with cases of suspected transient ischemic attacks (TIAs) who came to six institutions during a 21-month period were followed up. Factors were identified and prospectively analyzed for risk for further TIAs, stroke, and death. A history of multiple carotid artery TIAs was significantly related to further TIAs. A single TIA placed the patient at greater risk for early infarction. Older age, male sex, and unreliability to take dangerous medication were risk factors for cerebral infarction. Anticoagulant therapy, older age, male sex, diabetes mellitus, heart disease, abnormal ECG, and poor surgical risk were factors for death. The increased mortality associated with anticoagulants was confined to the older age group. While white patients treated with antiplatelet-aggregating agents had a lower mortality than those treated otherwise, this was not true among black patients.

(JAMA 240:742-746, 1978)

REFERENCES

ABSTRACT | REFERENCES

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Karp HR, Heyman A, Heyden S, et al: Transient cerebral ischemia: Prevalence and prognosis in a biracial rural community . JAMA 225:125-128, 1973;.

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Dyken ML, Conneally PM, Haerer AF, et al: Cooperative study of hospital frequency and character of transient ischemic attacks: I. Background, organization, and clinical survey . JAMA 237:882-886, 1977;.

Swanson PD, Calanchini PR, Dyken ML, et al: A cooperative study of hospital frequency and character of transient ischemic attacks: II. Performance of angiography among six centers . JAMA 237:2202-2206, 1977;.

Haerer AF, Gotshall RA, Conneally PM, et al: Cooperative study of hospital frequency and character of transient ischemic attacks: III. Variations in treatment . JAMA 238:142-146, 1977;.

Calanchini PR, Swanson PD, Gotshall RA, et al: Cooperative study of hospital frequency and character of transient ischemic attacks: IV. The reliability of diagnosis . JAMA 238:2029-2033, 1977;.

Futty DE, Conneally PM, Dyken ML, et al: Cooperative study of hospital frequency and character of transient ischemic attacks: V. Symptom analysis . JAMA 238:2386-2390, 1977;.

Price TR, Gotshall RA, Poskanzer DC, et al: Cooperative study of hospital frequency and character of transient ischemic attacks: VI. Patients examined during an attack . JAMA 238:2512-2515, 1977;.

Gotshall RA, Price TR, Haerer AF, et al: Cooperative study of hospital frequency and character of transient ischemic attacks: VII. Initial diagnostic evaluation . JAMA 239:2001-2003, 1978;.

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