Malignant Neoplasms Following Cardiac Transplantation FREE

John G. Krikorian, MD; Jeffrey L. Anderson, MD; Charles P. Bieber, MD; Israel Penn, MD; Edward B. Stinson, MD

[+] Author Affiliations

Reprint requests to Cardiology Division, Stanford University Medical Center, Stanford, CA 94305 (Dr Anderson).

JAMA. 1978;240(7):639-643. doi:10.1001/jama.1978.03290070041012

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ABSTRACT

ABSTRACT | REFERENCES

Between Jan 6, 1968, and April 11, 1977, 124 patients underwent cardiac transplantation at Stanford University Medical Center, with a mean and median period of follow-up of 18.3 and 9.7 months, respectively. Malignant neoplasms developed in seven patients—three lymphoproliferative neoplasms, two skin cancers, one acute leukemia, and one colon carcinoma. Visceral tumors were often fatal and caused 11% of deaths after three months following transplantation. The incidence and spectrum of malignant neoplasms in this population are similar to those observed in recipients of renal homografts.

(JAMA 240:639-643, 1978)

REFERENCES

ABSTRACT | REFERENCES

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Reimer RR, Hoover R, Fraumeni JF Jr, et al: Acute leukemia after alkylating-agent therapy of ovarian cancer . N Engl J Med 297:177-181, 1977;.

Svejgaard A, Platz P, Ryder LP, et al: HL-A and disease associations: A survey . Transplant Rev 22:3-43, 1975;.

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