Reprint requests to Department of Radiology, The Johns Hopkins Medical Institutions, 601 N Broadway, Baltimore, MD 21205 (Dr Lightman).
Edited by Z. Danilevicius, MD, Senior Editor.
SOME adults with complaints of weakness and fatigue have an underlying specific neuromuscular disease. In these patients the neuromuscular symptoms may be associated with potentially more serious nonneuromuscular abnormalities. The chest roentgenogram may provide a clue to the diagnosis of a systemic disorder responsible for muscular weakness.
Carcinomatous Neuromyopathy The most serious illness causing weakness is malignant neoplasm. The chest is a frequent site of metastases and often signals widespread disease. Primary lung cancer may be associated with a neuromuscular syndrome that is not indicative of widespread disease and that occasionally may be alleviated by resection of the pulmonary lesion. The combination of a primary malignant neoplasm and neuromuscular disease is called carcinomatous neuromyopathy. In 1963 Croft and Wilkinson1 studied 250 men with proved lung cancer and found a 16% incidence of neuromyopathy. This compared with a 1% to 2% incidence of neuromuscular symptoms in a control group. The
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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