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Acute Organic Brain Syndrome Associated With Gentamicin Therapy FREE

Gary J. Byrd, MD
[+] Author Affiliations

Reprint requests to Department of Psychiatry, Baylor College of Medicine, 1200 Moursund Ave, Houston, TX 77030 (Dr Byrd).


JAMA. 1977;238(1):53-54. doi:10.1001/jama.1977.03280010053022
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Two patients receiving gentamicin sulfate experienced acute organic brain syndromes that subsided after use of the drug was discontinued. Among the various factors considered as possible causes, time sequences point to gentamicin as the most likely.

(JAMA 238:53-54, 1977)

REFERENCES

Wadlington WB, Hatcher H, Turner DJ:  Osteomyelitis of the patella: Gentamicin therapy associated with encephalopathy . Clin Pediatr 10:577-580, 1971;.
Kane FJ, Byrd G:  Acute toxic psychosis associated with gentamicin therapy . South Med J 68:1283-1285, 1975;.
Jaffe JH, Martin WR:  Narcotic analgesics and antagonists , in Goodman LS, Gilman A (eds): The Pharmacological Basis of Therapeutics , ed 5. New York, The Macmillan Co Publishers, 1975;, pp 248-266.
Falco FG, Smith HM, Arcieri GM:  Nephrotoxicity of aminoglycosides and gentamicin . Infect Disc 119:406-409, 1969;.
Weinstein L:  Antimicrobial agents , in Goodman LS, Gilman A (eds): The Pharmacological Basis of Therapeutics , ed 5. New York, The Macmillan Co Publishers, 1975;, p 1174.

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Wadlington WB, Hatcher H, Turner DJ:  Osteomyelitis of the patella: Gentamicin therapy associated with encephalopathy . Clin Pediatr 10:577-580, 1971;.
Kane FJ, Byrd G:  Acute toxic psychosis associated with gentamicin therapy . South Med J 68:1283-1285, 1975;.
Jaffe JH, Martin WR:  Narcotic analgesics and antagonists , in Goodman LS, Gilman A (eds): The Pharmacological Basis of Therapeutics , ed 5. New York, The Macmillan Co Publishers, 1975;, pp 248-266.
Falco FG, Smith HM, Arcieri GM:  Nephrotoxicity of aminoglycosides and gentamicin . Infect Disc 119:406-409, 1969;.
Weinstein L:  Antimicrobial agents , in Goodman LS, Gilman A (eds): The Pharmacological Basis of Therapeutics , ed 5. New York, The Macmillan Co Publishers, 1975;, p 1174.
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