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ARTICLE |

Nephritogenic Streptococcus Antigen FREE

Samuel Vaisrub, MD
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JAMA. 1977;237(10):997-997. doi:10.1001/jama.1977.03270370069029
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In a recent communication, Reeves1 listed five areas of concern to clinical immunologists: immunodeficiency, lymphoproliferative disorders, autoimmune diseases, heteroimmune diseases, and therapeutic aspects of immunology. Surprisingly, he failed to mention infectious diseases, so closely linked historically and developmentally to immunology. For this omission, Reeves was taken to task by Bryceson,2 who ascribed it to the gap that has developed in British medicine between immunology and the study of infectious disease—a gap for which preoccupation with chemotherapy may be partly responsible.

It is possible that Reeves neglected to include infectious disease because the link between it and immunology is so selfevident as to be taken for granted. Whatever the reason, the increasingly strengthening bond between immunology and infectious disease is easily recognized even by the layman who follows the swine flu saga or reads about new vaccines for rabies and hepatitis B.

The physician, of course, need not be

REFERENCES

Reeves WG:  Clinical immunology: Nature of the specialty and provision of facilities . Lancet 2:459-461, 1976;.
Bryceson A:  Clinical immunology . Lancet 2:685-686, 1976;.
Lange K, Ahmed U, Kleinberger H, et al:  A hitherto unknown streptococcal antigen and its probable relation to acute poststreptococcal glomerulonephritis . Clin Nephrol 5:207-215, 1976;.
Markowitz AS, Lange CF Jr:  Streptococcal related glomerulonephritis. I. Isolation, immunochemistry and comparative chemistry of soluble fractions from type 12 nephritogenic streptococci and human glomerule . J Immunol 92:565-575, 1964;.
Seegal BC, Andres GA, Hsu KC, et al:  Studies on the pathogenics of acute and progressive glomerulonephritis in man by immunofluorescein and immunoferritin techniques . Fed Proc 24:100, 1965;.
Michael AF Jr, Drummond KN, Good RA, et al:  Acute poststreptococcal glomerulonephritis: Immune deposit disease . J Clin Invest 45:237-248, 1966;.
Treser G, Semar M, McVicar M, et al:  Antigenic streptococcal components in acute glomerulonephritis . Science 163:676-677, 1969;.

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Reeves WG:  Clinical immunology: Nature of the specialty and provision of facilities . Lancet 2:459-461, 1976;.
Bryceson A:  Clinical immunology . Lancet 2:685-686, 1976;.
Lange K, Ahmed U, Kleinberger H, et al:  A hitherto unknown streptococcal antigen and its probable relation to acute poststreptococcal glomerulonephritis . Clin Nephrol 5:207-215, 1976;.
Markowitz AS, Lange CF Jr:  Streptococcal related glomerulonephritis. I. Isolation, immunochemistry and comparative chemistry of soluble fractions from type 12 nephritogenic streptococci and human glomerule . J Immunol 92:565-575, 1964;.
Seegal BC, Andres GA, Hsu KC, et al:  Studies on the pathogenics of acute and progressive glomerulonephritis in man by immunofluorescein and immunoferritin techniques . Fed Proc 24:100, 1965;.
Michael AF Jr, Drummond KN, Good RA, et al:  Acute poststreptococcal glomerulonephritis: Immune deposit disease . J Clin Invest 45:237-248, 1966;.
Treser G, Semar M, McVicar M, et al:  Antigenic streptococcal components in acute glomerulonephritis . Science 163:676-677, 1969;.
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