Reprint requests to Mercy Hospital, 1400 Locust St, Pittsburgh, PA 15219 (Dr Orchard).
THE ZOLLINGER-ELLISON syndrome is associated with hypersecretion of gastric acid, usually owing to gastrin-secreting pancreatic tumors. Hemorrhage or perforation are complications of the malignant peptic ulcer diathesis. The recommended treatment is total gastrectomy. This case of Zollinger-Ellison syndrome is reported to illustrate an alternative treatment for patients unable to tolerate total gastrectomy.
Report of a Case A 72-year-old man underwent gastroenterostomy and vagotomy in 1972 for a bleeding duodenal peptic ulcer. Intermittent episodes of epigastric pain for the next four years were treated with antacids. He was admitted on May 17, 1976, with epigastric pain, weakness, and melena, but no diarrhea; hemoglobin level was 6 gm/dl. A large duodenal ulcer was demonstrated radiographically. The basal acid output was 17 mEq/hr, and maximal acid output was 35 mEq/hr. Fasting serum gastrin level was 433 and 600 pg/ml on two occasions (normal, less than 170 pg/ml. Following a bolus of secretin (2
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
Instructions
Comments are moderated and will appear on the site at the discretion of the Journal of American Medical Association editors. Comments should not exceed 500 words of text and 10 references.
Do not submit personal medical questions or information that could identify a specific patient, questions about a particular case, or general inquiries to an author. Only content that has not been published, posted, or submitted elsewhere should be submitted. By submitting this Comment, you and any coauthors transfer copyright to the journal if your Comment is posted.
* = Required Field
Disclosure of Any Conflicts of Interest* Indicate all relevant conflicts of interest of each author below, including all relevant financial interests, activities, and relationships within the past 3 years including, but not limited to, employment, affiliation, grants or funding, consultancies, honoraria or payment, speakers’ bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued. If all authors have none, check "No potential conflicts or relevant financial interests" in the box below. Please also indicate any funding received in support of this work. The information will be posted with your response.
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Customize your page view by dragging & repositioning the boxes below.
and access these and other features:
Register Now
Enter your username and email address. We'll send you a reminder to the email address on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.