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Prescribing of Tetracycline to Children Less Than 8 Years Old: Title and subTitle BreakA Two-Year Epidemiologic Study Among Ambulatory Tennessee Medicaid Recipients FREE

Wayne A. Ray, MS; Charles F. Federspiel, PhD; William Schaffner, MD
[+] Author Affiliations

Reprint requests to Division of Biostatistics, Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 (Mr Ray).


JAMA. 1977;237(19):2069-2074. doi:10.1001/jama.1977.03270460055020
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The Committee on Drugs of the American Academy of Pediatrics finds virtually no indications for administering tetracyclines to children less than 8 years old. This study analyzes tetracycline prescribing to ambulatory children less than 8 years of age in the Tennessee Medicaid program during a two-year period. Of the nearly 59,000 children in the study, 4,026 (7%) received 7,046 tetracycline prescriptions. Twenty-seven percent (527) of 1,947 participating physicians prescribed tetracycline; 26 physicians (5%) wrote 54% of the prescriptions for 45% of the children. Physicians in family practice prescribed the greatest quantity of tetracycline. Surgeons and internists prescribed more tetracycline to young children than did pediatricians. Rural location of practice was independently associated with increased tetracycline prescribing for all specialties. Recent graduates from medical school were less apt to prescribe tetracycline than were earlier graduates.

(JAMA 237:2069-2074, 1977)

REFERENCES

 Requiem for tetracyclines. Committee on Drugs of the American Academy of Pediatrics . Pediatrics 55:142-143, 1975;.
Federspiel CF, Ray WA, Schaffner W:  Medicaid records as a valid data source: The Tennessee experience . Med Care 14:166-172, 1976;.
Ray WA, Federspiel CF, Schaffner W:  Prescribing of chloramphenicol in ambulatory practice: An epidemiologic study among Tennessee Medicaid recipients . Ann Intern Med 84:266-270, 1976;.
Annual Bulletin of Vital Statistics for 1971 . Nashville, State of Tennessee Department of Public Health, pp 7-8, 1973;.
Kullback S: Information Theory and Statistics . New York, John Wiley & Sons Inc, 1959;, pp 155-188.
Hogg RV, Craig AT: Introduction to Mathematical Statistics . London, Macmillan & Co Ltd, 1970;, pp 186-188, 254-257.
 Estimates of the population of states, by age: July 1, 1973 and 1974 , in Current Population Reports , Series P-25, No. (539) . US Bureau of the Census, January 1975;.
McCormack RC, Kaye D, Hook EW:  Resistance of group A streptococci to tetracycline . N Engl J Med 267:323-326, 1962;.
Becker MH, Stolley PD, Lasagna L, et al:  Characteristics and attitudes of physicians associated with the prescribing of chloramphenicol . HSMHA Health Rep 86:993-1003, 1971;.
Meade TW:  Prescribing of chloramphenicol in general practice . Br Med J 1:671-674, 1967;.
Wade OL:  Prescribing of chloramphenicol and aplastic anemia . J Coll Gen Pract 12:277-286, 1966;.

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 Requiem for tetracyclines. Committee on Drugs of the American Academy of Pediatrics . Pediatrics 55:142-143, 1975;.
Federspiel CF, Ray WA, Schaffner W:  Medicaid records as a valid data source: The Tennessee experience . Med Care 14:166-172, 1976;.
Ray WA, Federspiel CF, Schaffner W:  Prescribing of chloramphenicol in ambulatory practice: An epidemiologic study among Tennessee Medicaid recipients . Ann Intern Med 84:266-270, 1976;.
Annual Bulletin of Vital Statistics for 1971 . Nashville, State of Tennessee Department of Public Health, pp 7-8, 1973;.
Kullback S: Information Theory and Statistics . New York, John Wiley & Sons Inc, 1959;, pp 155-188.
Hogg RV, Craig AT: Introduction to Mathematical Statistics . London, Macmillan & Co Ltd, 1970;, pp 186-188, 254-257.
 Estimates of the population of states, by age: July 1, 1973 and 1974 , in Current Population Reports , Series P-25, No. (539) . US Bureau of the Census, January 1975;.
McCormack RC, Kaye D, Hook EW:  Resistance of group A streptococci to tetracycline . N Engl J Med 267:323-326, 1962;.
Becker MH, Stolley PD, Lasagna L, et al:  Characteristics and attitudes of physicians associated with the prescribing of chloramphenicol . HSMHA Health Rep 86:993-1003, 1971;.
Meade TW:  Prescribing of chloramphenicol in general practice . Br Med J 1:671-674, 1967;.
Wade OL:  Prescribing of chloramphenicol and aplastic anemia . J Coll Gen Pract 12:277-286, 1966;.
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