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Neonatal Meningitis and Mastoiditis Caused by Hemophilus influenzae FREE

Tay B. Lee, MD; Walter H. Stingle, MD; Pamela Ombres, MD; John S. Lewis, MD; Louis Z. Cooper, MD
[+] Author Affiliations

Reprint requests to the Pediatric Service, Roosevelt Hospital, 428 W 59th St, New York, NY 10019 (Dr Cooper).


JAMA. 1976;235(4):407-409. doi:10.1001/jama.1976.03260300033027
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A newborn infant developed Hemophilus influenzae meningitis associated with acute coalescent mastoiditis and a cutaneous abscess in the mastoid region. Mastoidectomy was followed by prompt recovery from the meningitis, which had failed to clear previously despite antibiotic therapy. Mastoiditis may exist as an infective focus in neonatal meningitis more frequently than has been appreciated. Mastoid roentgenograms are usually the only clue to diagnosis of this infection and should be obtained in patients with neonatal meningitis responding poorly to antibiotic therapy.

(JAMA 235:407-409, 1976)

REFERENCES

Sell SHW:  The clinical importance of Hemophilus influenzae infection in children . Pediatr Clin North Am 17:415-426, 1970;.
Mathies AWJ, Hodgman J, Ivler D:  Hemophilus influenzae meningitis in a premature infant . Pediatrics 35:791-792, 1965;.
Watson DG:  Purulent neonatal meningitis . J Pediatr 50:352-360, 1957;.
Collier AM, Conner JD, Nyhan WL:  Systemic infection with Hemophilus influenzae in very young infants . J Pediatr 70:539-547, 1967;.
Sproles ET, Azerrad J, Williamson C, et al:  Meningitis due to Hemophilus influenzae: Longterm sequelae . J Pediatr 75:782-788, 1969;.
Graber CD, Gershanik JJ, Levkoff AH, et al:  Changing pattern of neonatal susceptibility to Hemophilus influenzae . J Pediatr 78:948-950, 1971;.
McDonald R:  Purulent meningitis in newborn babies . Clin Pediatr 11:450-453, 1972;.
Ziai M, Haggerty RJ:  Neonatal meningitis . N Engl J Med 259:314-320, 1958;.
Hemsath FA:  Intra-uterine and neonatal otitis: Study of seven cases including case of otitic meningitis . Arch Otolaryngol 23:78-92, 1936;.
Eggston AA, Wolff S: Histopathology of the Ear, Nose, and Throat . Baltimore, Williams and Wilkins Co, 1947;, pp 333-367.
Bland RD:  Otitis media in the first six weeks of life: Diagnosis, bacteriology, and management . Pediatrics 49:187-197, 1972;.
Sanders DY:  Failure of response to ampicillin in Hemophilus influenzae meningitis . Am J Dis Child 117:331-333, 1969;.

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Sell SHW:  The clinical importance of Hemophilus influenzae infection in children . Pediatr Clin North Am 17:415-426, 1970;.
Mathies AWJ, Hodgman J, Ivler D:  Hemophilus influenzae meningitis in a premature infant . Pediatrics 35:791-792, 1965;.
Watson DG:  Purulent neonatal meningitis . J Pediatr 50:352-360, 1957;.
Collier AM, Conner JD, Nyhan WL:  Systemic infection with Hemophilus influenzae in very young infants . J Pediatr 70:539-547, 1967;.
Sproles ET, Azerrad J, Williamson C, et al:  Meningitis due to Hemophilus influenzae: Longterm sequelae . J Pediatr 75:782-788, 1969;.
Graber CD, Gershanik JJ, Levkoff AH, et al:  Changing pattern of neonatal susceptibility to Hemophilus influenzae . J Pediatr 78:948-950, 1971;.
McDonald R:  Purulent meningitis in newborn babies . Clin Pediatr 11:450-453, 1972;.
Ziai M, Haggerty RJ:  Neonatal meningitis . N Engl J Med 259:314-320, 1958;.
Hemsath FA:  Intra-uterine and neonatal otitis: Study of seven cases including case of otitic meningitis . Arch Otolaryngol 23:78-92, 1936;.
Eggston AA, Wolff S: Histopathology of the Ear, Nose, and Throat . Baltimore, Williams and Wilkins Co, 1947;, pp 333-367.
Bland RD:  Otitis media in the first six weeks of life: Diagnosis, bacteriology, and management . Pediatrics 49:187-197, 1972;.
Sanders DY:  Failure of response to ampicillin in Hemophilus influenzae meningitis . Am J Dis Child 117:331-333, 1969;.
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