0
May 31, 1976, Vol 235, No. 22 >
ARTICLE | May 31, 1976

Acquired Zinc Deficiency: Title and subTitle BreakCutaneous Manifestations Typical of Acrodermatitis Enteropathica FREE

Stephen B. Tucker, MD; Arnold L. Schroeter, MD; Philip W. Brown, Jr, MD; John T. McCall, PhD
[+] Author Affiliations

Reprint requests to Mayo Clinic, 200 First St SW, Rochester, MN 55901 (Dr Schroeter).


JAMA. 1976;235(22):2399-2402. doi:10.1001/jama.1976.03260480019022
Text Size: A A A
Published online
Article
References

A patient given long-term total parenteral nutrition acquired a zinc deficiency severe enough to cause typical cutaneous manifestations of acrodermatitis enteropathica. This report, the first detailed one, to our knowledge, of such an association, adds to the accumulating evidence that supplementation of trace elements is needed in long-term parenteral nutrition.

(JAMA 235:2399-2402, 1976)

REFERENCES

1 +
Shils ME:  Minerals in total parenteral nutrition . Drug Intel Clin Pharm 6:385-392, 1972;.
2 +
Vilter RW, Bozian RC, Hess EV, et al:  Manifestations of copper deficiency in a patient with systemic sclerosis on intravenous hyperalimentation . N Engl J Med 291:188-191, 1974;.
3 +
McMahon RA, Parker ML, McKinnon MC:  Zinc treatment in malabsorption . Med J Aust 2:210-212, 1968;.
4 +
Tasman-Jones C, Kay RG:  Zinc deficiency and skin lesions . N Engl J Med 293:830, 1975;.
5 +
Amador M, Peña M, García-Miranda A, et al:  Low hair-zinc concentrations in acrodermatitis enteropathica . Lancet 1:1379, 1975;.
6 +
Petering HG, Yeager DW, Witherup SO:  Trace metal content of hair: I. Zinc and copper content of human hair in relation to age and sex . Arch Environ Health 23:202-207, 1971;.
7 +
Prasad AS, Oberleas D: Zinc:  Human nutrition and metabolic effects . Ann Intern Med 73:631-636, 1970;.
8 +
Sandstead HH:  Zinc nutrition in the United States . Am J Clin Nutr 26:1251-1260, 1973;.
9 +
Prasad AS, Halsted JA, Nadimi M:  Syndrome of iron deficiency anemia, hepatosplenomegaly, hypogonadism, dwarfism and geophagia . Am J Med 31:532-546, 1961;.
10 +
Moynahan EJ, Barnes PM:  Zinc deficiency and a synthetic diet for lactose intolerance . Lancet 1:676-677, 1973;.
11 +
Neldner KH, Hambidge KM:  Zinc therapy of acrodermatitis enteropathica . N Engl J Med 292:879-882, 1975;.
12 +
Halsted JA, Smith JC Jr:  Plasma-zinc in health and disease . Lancet 1:322-324, 1970;.
13 +
Strain WH, Steadman LT, Lankau CA Jr, et al:  Analysis of zinc levels in hair for the diagnosis of zinc deficiency in man . J Lab Clin Med 68:244-249, 1966;.
14 +
Hambidge KM:  Zinc deficiency in children , in Hoekstra WG, Suttie JW, Ganther HE, et al (eds): Trace Element Metabolism in Animals—2 . Baltimore, University Park Press, 1974;, pp 171-182.
15 +
Harrison WW, Yurachek JP, Benson CA:  The determination of trace elements in human hair by atomic absorption spectroscopy . Clin Chim Acta 23:83-91, 1969;.
16 +
Cornelis R:  Neutron activation analysis of hair: Failure of a mission . J Radioanal Chem 15:305-316, 1973;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Shils ME:  Minerals in total parenteral nutrition . Drug Intel Clin Pharm 6:385-392, 1972;.
2 +
Vilter RW, Bozian RC, Hess EV, et al:  Manifestations of copper deficiency in a patient with systemic sclerosis on intravenous hyperalimentation . N Engl J Med 291:188-191, 1974;.
3 +
McMahon RA, Parker ML, McKinnon MC:  Zinc treatment in malabsorption . Med J Aust 2:210-212, 1968;.
4 +
Tasman-Jones C, Kay RG:  Zinc deficiency and skin lesions . N Engl J Med 293:830, 1975;.
5 +
Amador M, Peña M, García-Miranda A, et al:  Low hair-zinc concentrations in acrodermatitis enteropathica . Lancet 1:1379, 1975;.
6 +
Petering HG, Yeager DW, Witherup SO:  Trace metal content of hair: I. Zinc and copper content of human hair in relation to age and sex . Arch Environ Health 23:202-207, 1971;.
7 +
Prasad AS, Oberleas D: Zinc:  Human nutrition and metabolic effects . Ann Intern Med 73:631-636, 1970;.
8 +
Sandstead HH:  Zinc nutrition in the United States . Am J Clin Nutr 26:1251-1260, 1973;.
9 +
Prasad AS, Halsted JA, Nadimi M:  Syndrome of iron deficiency anemia, hepatosplenomegaly, hypogonadism, dwarfism and geophagia . Am J Med 31:532-546, 1961;.
10 +
Moynahan EJ, Barnes PM:  Zinc deficiency and a synthetic diet for lactose intolerance . Lancet 1:676-677, 1973;.
11 +
Neldner KH, Hambidge KM:  Zinc therapy of acrodermatitis enteropathica . N Engl J Med 292:879-882, 1975;.
12 +
Halsted JA, Smith JC Jr:  Plasma-zinc in health and disease . Lancet 1:322-324, 1970;.
13 +
Strain WH, Steadman LT, Lankau CA Jr, et al:  Analysis of zinc levels in hair for the diagnosis of zinc deficiency in man . J Lab Clin Med 68:244-249, 1966;.
14 +
Hambidge KM:  Zinc deficiency in children , in Hoekstra WG, Suttie JW, Ganther HE, et al (eds): Trace Element Metabolism in Animals—2 . Baltimore, University Park Press, 1974;, pp 171-182.
15 +
Harrison WW, Yurachek JP, Benson CA:  The determination of trace elements in human hair by atomic absorption spectroscopy . Clin Chim Acta 23:83-91, 1969;.
16 +
Cornelis R:  Neutron activation analysis of hair: Failure of a mission . J Radioanal Chem 15:305-316, 1973;.

Letters

Submit a Letter
CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2012 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems