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Glucose-6-Phosphate Dehydrogenase Deficiency in Military Recruits FREE

LCDR David E. Uddin, MSCCAPT ; Larry G. Dickson, MCCAPT ; Charles E. Brodine, MC
[+] Author Affiliations

The opinions or assertions contained herein are the private ones of the authors and are not to be construed as official or reflecting the views of the Navy Department or the Naval Service at large.

Reprint requests to Clinical Medical Sciences Department, Naval Medical Research Institute, National Naval Medical Center, 8901 Rockville Pike, Bethesda, MD 20014 (Dr. Uddin).


JAMA. 1974;227(12):1408-1409. doi:10.1001/jama.1974.03230250032024
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A survey was conducted to determine the incidence of erythrocyte glucose6-phosphate dehydrogenase (G6PD) deficiency in Navy and Marine Corps black, male recruits. The incidence of G6PD deficiency in 20,810 recruits was 12.6%. The incidence of G6PD deficiency in individuals with hemoglobin AS trait or hemoglobin AC trait was the same as the incidence in persons with hemoglobin A. Automated testing of large numbers of persons for G6PD deficiency is technically feasible.

REFERENCES

Carson PE, et al:  Enzymatic deficiency in primaquine sensitive erythrocytes . Science 124:484-485, 1956;.
Keller DF: Erythrocyte Glucose-6-Phosphate Dehydrogenase Deficiency: A Pharmacogenetic Prototype . Cleveland, CRC Press, 1970;.
Dimson SB, McMartin RB:  Pamaquin haemoglobinuria . Q J Med 15:25-46, 1946;.
Dickson LG, Johnson DR, Johnson C:  Automated fluorometric method for screening for glucose-6-phosphate dehydrogenase deficiency . Clin Chem 19:301-303, 1973;.
Beutler E, Mitchell M:  Special modifications of the fluorescent screening method for glucose-6-phosphate dehydrogenase . Blood 32:816-818, 1968;.
Yoshida A:  Hemolytic anemia and G6PD deficiency . Science 179:532-537, 1973;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Carson PE, et al:  Enzymatic deficiency in primaquine sensitive erythrocytes . Science 124:484-485, 1956;.
Keller DF: Erythrocyte Glucose-6-Phosphate Dehydrogenase Deficiency: A Pharmacogenetic Prototype . Cleveland, CRC Press, 1970;.
Dimson SB, McMartin RB:  Pamaquin haemoglobinuria . Q J Med 15:25-46, 1946;.
Dickson LG, Johnson DR, Johnson C:  Automated fluorometric method for screening for glucose-6-phosphate dehydrogenase deficiency . Clin Chem 19:301-303, 1973;.
Beutler E, Mitchell M:  Special modifications of the fluorescent screening method for glucose-6-phosphate dehydrogenase . Blood 32:816-818, 1968;.
Yoshida A:  Hemolytic anemia and G6PD deficiency . Science 179:532-537, 1973;.
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