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August 13, 1973, Vol 225, No. 7 >
ARTICLE | August 13, 1973

Ventricular Septal Defects After Myocardial Infarction: Title and subTitle BreakEarly Operative Treatment FREE

Anthony F. Graham, MD; Edward B. Stinson, MD; Pat O. Daily, MD; Donald C. Harrison, MD
[+] Author Affiliations

Reprint requests to Cardiology Division, Stanford University School of Medicine, Stanford, CA 94305 (Dr. Harrison).


JAMA. 1973;225(7):708-711. doi:10.1001/jama.1973.03220340022005
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References

Twelve patients underwent emergency operative closure of a ventricular septal defect (VSD) occurring as a complication of acute myocardial infarction. Operations were performed an average of eight days following infarction, and five days after the appearance of the VSD. All patients were in cardiogenic shock or intractable congestive heart failure. Operative repair involved closure of the septal defect with the use of a Teflon patch and pledgets for support. In addition, an infarctectomy or aneurysmectomy was performed in most of the survivors. Six patients are alive 6 to 54 months after operation (average, 22 months). Successful early operative closure of a postinfarction VSD can be accomplished, with an encouraging survival rate. The major factor determining survival was the function of the remaining myocardium.

REFERENCES

1 +
Latham PM: Lectures on Subjects Connected With Clinical Medicine, Comprising Diseases of the Heart , vol 2. London, Longmans, Green & Co Ltd, 1845;,p 168.
2 +
Diaz-Rivera RS, Miller AJ:  Rupture of the heart following acute myocardial infarction: Incidence in a public hospital with five illustrative cases including one of perforation of the interventricular septum diagnosed antemortem . Am Heart J 35:126-135, 1948;.
3 +
Lee WY, Cadon L, Slodki SJ:  Perforation of infarcted interventricular septum . Arch Intern Med 190:731-741, 1962;.
4 +
Sanders RJ, Kern WH, Blount SG Jr:  Perforation of the interventricular septum complicating myocardial infarction: A report of eight cases, one with cardiac catheterization . Am Heart J 51:736-748, 1956;.
5 +
Oyamada A, Queen FB:  Spontaneous rupture of the interventricular septum following acute myocardial infarction with some clinicopathological observations on survival in five cases . Read before the Pan Pacific Pathology Congress, Tripler US Army Hospital, Honolulu, Oct 12,1961 .
6 +
Landale DG, Schlappi JC:  Thirteen year survival with acquired interventricular septal defect after myocardial infarction . Am Heart J 64:33-36, 1962;.
7 +
Cooley DA, et al:  Surgical repair of ruptured interventricular septum following acute myocardial infarction . Surgery 41:930-937, 1957;.
8 +
Boicourt OW, et al:  Rupture of the interventricular septum . Circulation 26:1321-1328, 1962;.
9 +
Collis JL, et al:  Repair of acquired interventricular septal defect following myocardial infarction . Lancet 2:172-175, 1962;.
10 +
Dobell ARC, et al:  Surgical closure of interventricular septal perforation complicating myocardial infarction . J Thorac Cardiovasc Surg 43:802-809, 1962;.
11 +
Stinson EB, Becker J, Shumway NE:  Successful repair of postinfarction ventricular septal defect and biventricular aneurysm . J Thorac Cardiovasc Surg 58:20-24, 1969;.
12 +
Iben AB, et al:  Surgical treatment of postinfarction ventricular septal defects . Ann Thorac Surg 8:252-262, 1969;.
13 +
Daicoff GR, Rhodes ML:  Surgical repair of ventricular septal rupture and ventricular aneurysm . JAMA 203:115-118, 1968;.
14 +
Kitamura S, Mendez A, Kay JH:  Ventricular septal defect following myocardial infarction . J Thorac Cardiovasc Surg 61:186-199, 1971;.
15 +
Moss AJ, et al:  Combined septal rupture repair and infarctectomy in acute myocardial infarction . JAMA 213:460-462, 1970;.
16 +
Freeny PC, et al:  Ventricular septal defect and ventricular aneurysm secondary to acute myocardial infarction . Circulation 43:360-363, 1971;.
17 +
Taylor FH, Citron DS, Robicsek F:  Simultaneous repair of ventricular aneurysm following myocardial infarction . Am Thoracic Surg 1:72-79, 1965;.
18 +
Geary DJ, Schwartz MJ, Loomis Bell A:  Postmyocardial infarction ventricular aneurysm septal tear syndrome . Chest 60:583-586, 1971;.

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1 +
Latham PM: Lectures on Subjects Connected With Clinical Medicine, Comprising Diseases of the Heart , vol 2. London, Longmans, Green & Co Ltd, 1845;,p 168.
2 +
Diaz-Rivera RS, Miller AJ:  Rupture of the heart following acute myocardial infarction: Incidence in a public hospital with five illustrative cases including one of perforation of the interventricular septum diagnosed antemortem . Am Heart J 35:126-135, 1948;.
3 +
Lee WY, Cadon L, Slodki SJ:  Perforation of infarcted interventricular septum . Arch Intern Med 190:731-741, 1962;.
4 +
Sanders RJ, Kern WH, Blount SG Jr:  Perforation of the interventricular septum complicating myocardial infarction: A report of eight cases, one with cardiac catheterization . Am Heart J 51:736-748, 1956;.
5 +
Oyamada A, Queen FB:  Spontaneous rupture of the interventricular septum following acute myocardial infarction with some clinicopathological observations on survival in five cases . Read before the Pan Pacific Pathology Congress, Tripler US Army Hospital, Honolulu, Oct 12,1961 .
6 +
Landale DG, Schlappi JC:  Thirteen year survival with acquired interventricular septal defect after myocardial infarction . Am Heart J 64:33-36, 1962;.
7 +
Cooley DA, et al:  Surgical repair of ruptured interventricular septum following acute myocardial infarction . Surgery 41:930-937, 1957;.
8 +
Boicourt OW, et al:  Rupture of the interventricular septum . Circulation 26:1321-1328, 1962;.
9 +
Collis JL, et al:  Repair of acquired interventricular septal defect following myocardial infarction . Lancet 2:172-175, 1962;.
10 +
Dobell ARC, et al:  Surgical closure of interventricular septal perforation complicating myocardial infarction . J Thorac Cardiovasc Surg 43:802-809, 1962;.
11 +
Stinson EB, Becker J, Shumway NE:  Successful repair of postinfarction ventricular septal defect and biventricular aneurysm . J Thorac Cardiovasc Surg 58:20-24, 1969;.
12 +
Iben AB, et al:  Surgical treatment of postinfarction ventricular septal defects . Ann Thorac Surg 8:252-262, 1969;.
13 +
Daicoff GR, Rhodes ML:  Surgical repair of ventricular septal rupture and ventricular aneurysm . JAMA 203:115-118, 1968;.
14 +
Kitamura S, Mendez A, Kay JH:  Ventricular septal defect following myocardial infarction . J Thorac Cardiovasc Surg 61:186-199, 1971;.
15 +
Moss AJ, et al:  Combined septal rupture repair and infarctectomy in acute myocardial infarction . JAMA 213:460-462, 1970;.
16 +
Freeny PC, et al:  Ventricular septal defect and ventricular aneurysm secondary to acute myocardial infarction . Circulation 43:360-363, 1971;.
17 +
Taylor FH, Citron DS, Robicsek F:  Simultaneous repair of ventricular aneurysm following myocardial infarction . Am Thoracic Surg 1:72-79, 1965;.
18 +
Geary DJ, Schwartz MJ, Loomis Bell A:  Postmyocardial infarction ventricular aneurysm septal tear syndrome . Chest 60:583-586, 1971;.

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