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Hyperuricemia, Gout, and the Executive Suite FREE

Jack L. Katz, MD; Herbert Weiner, MD; Alexander Gutman, MD; Ts'ai-Fan Yu, MD
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JAMA. 1973;224(9):1251-1257. doi:10.1001/jama.1973.03220230017005
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Eight pairs of adult brothers (in one instance, actually first cousins raised together), all with family histories of gout and therefore likely to have hyperuricemia, were examined for possible correlations between achievement-related variables and relative serum uric acid (SUA) levels within each pair. Manifest achievement, achievement orientation, and achievement drive did not reliably predict which brother in each pair possessed the higher SUA level. However, when the variable of obesitydietary content was employed, significant predictive success was attained. Obesity did not correlate with achievement drive. However, the tonic and phasic eating histories of our subjects do suggest a possible explanation for the previous reports of a correlation between SUA level and such achievement-related variables.

REFERENCES

Mueller EF, et al:  Psychosocial correlates of serum urate levels . Psychol Bull 73:238-257, 1970;.
Katz JL, Weiner H:  Psychosomatic considerations in hyperuricemia and gout . Psychosom Med 34:165-182, 1972;.
Talbott JH: Gout , ed 3. New York, Grune & Stratton Inc, 1967;.
Wyngaarden JB:  Etiology and pathogenesis of gout , in Hollander JL, McCarty DJ (eds): Arthritis and Allied Conditions , ed 8. Philadelphia, Lea & Febiger Publishers, 1972;, pp 1071-1111.
Cattell RB, et al: The Motivation Analysis Test . Champaign, Ill, Institute for Personality and Ability Testing, 1964;, pp 1-27.
Cattell RB, Butcher HJ: The Prediction of Achievement . Indianapolis, Bobbs-Merrill Co. Inc, 1968;.
Yu TF, et al:  Rarity of X-linked partial hypoxanthine-guanine phosphoribosyltransferase deficiency in a large gouty population . Ann Intern Med 76:255-264, 1972;.
Hall AP:  Correlations among hyperuricemia hypercholesterolemia, coronary disease and hypertension . Arthritis Rheum 8:846-852, 1965;.
Orowan E: Origin of man . Nature 175:683-684, 1955;.
Seegmiller JE, Rosenbloom FM, Kelly WN:  An enzyme defect associated with a sexlinked human neurological disorder and excessive purine synthesis . Science 155:1682-1684, 1967;.
Lesch MA, Nyhan WL:  A familial disorder of uric acid metabolism and central nervous system function . Am J Med 36:561-570, 1964;.
Anumonye A, et al:  Plasma uric acid concentrations among Edinburgh business executives . JAMA 208:1141-1144, 1969;.
Brooks GW, Mueller E:  Serum urate concentrations among university professors: Relation to drive, achievement, leadership . JAMA 195:415-418, 1966;.
Dunn JP, et al:  Social class gradient of serum uric acid levels in males . JAMA 185:431-436, 1963;.
Stunkard A, et al:  Influence of social class on obesity and thinness in children . JAMA 221:579-584, 1972;.
Lanese RR, Gresham GE, Keller MD:  Behavioral and physiological characteristics in hyperuricemia . JAMA 207:1878-1882, 1969;.
Brøchner-Mortensen K:  Heberden oration, 1957 : Gout. Ann Rheum Dis 18:1-8, 1958;.
Acheson RM, Chan YK:  New Haven survey of joint diseases: The prediction of serum uric acid in a general population . J Chronic Dis 21:543-553, 1969;.
Rahe RH, et al:  Serum uric acid and cholesterol variability: A comprehensive view of underwater demolition team training . JAMA 206:2875-2880, 1968;.
Kasl SV, Cobb S, Brooks GW:  Changes in serum uric acid and cholesterol levels in men undergoing job loss . JAMA 206:1500-1507, 1968;.

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Mueller EF, et al:  Psychosocial correlates of serum urate levels . Psychol Bull 73:238-257, 1970;.
Katz JL, Weiner H:  Psychosomatic considerations in hyperuricemia and gout . Psychosom Med 34:165-182, 1972;.
Talbott JH: Gout , ed 3. New York, Grune & Stratton Inc, 1967;.
Wyngaarden JB:  Etiology and pathogenesis of gout , in Hollander JL, McCarty DJ (eds): Arthritis and Allied Conditions , ed 8. Philadelphia, Lea & Febiger Publishers, 1972;, pp 1071-1111.
Cattell RB, et al: The Motivation Analysis Test . Champaign, Ill, Institute for Personality and Ability Testing, 1964;, pp 1-27.
Cattell RB, Butcher HJ: The Prediction of Achievement . Indianapolis, Bobbs-Merrill Co. Inc, 1968;.
Yu TF, et al:  Rarity of X-linked partial hypoxanthine-guanine phosphoribosyltransferase deficiency in a large gouty population . Ann Intern Med 76:255-264, 1972;.
Hall AP:  Correlations among hyperuricemia hypercholesterolemia, coronary disease and hypertension . Arthritis Rheum 8:846-852, 1965;.
Orowan E: Origin of man . Nature 175:683-684, 1955;.
Seegmiller JE, Rosenbloom FM, Kelly WN:  An enzyme defect associated with a sexlinked human neurological disorder and excessive purine synthesis . Science 155:1682-1684, 1967;.
Lesch MA, Nyhan WL:  A familial disorder of uric acid metabolism and central nervous system function . Am J Med 36:561-570, 1964;.
Anumonye A, et al:  Plasma uric acid concentrations among Edinburgh business executives . JAMA 208:1141-1144, 1969;.
Brooks GW, Mueller E:  Serum urate concentrations among university professors: Relation to drive, achievement, leadership . JAMA 195:415-418, 1966;.
Dunn JP, et al:  Social class gradient of serum uric acid levels in males . JAMA 185:431-436, 1963;.
Stunkard A, et al:  Influence of social class on obesity and thinness in children . JAMA 221:579-584, 1972;.
Lanese RR, Gresham GE, Keller MD:  Behavioral and physiological characteristics in hyperuricemia . JAMA 207:1878-1882, 1969;.
Brøchner-Mortensen K:  Heberden oration, 1957 : Gout. Ann Rheum Dis 18:1-8, 1958;.
Acheson RM, Chan YK:  New Haven survey of joint diseases: The prediction of serum uric acid in a general population . J Chronic Dis 21:543-553, 1969;.
Rahe RH, et al:  Serum uric acid and cholesterol variability: A comprehensive view of underwater demolition team training . JAMA 206:2875-2880, 1968;.
Kasl SV, Cobb S, Brooks GW:  Changes in serum uric acid and cholesterol levels in men undergoing job loss . JAMA 206:1500-1507, 1968;.
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