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ARTICLE |

Abdominal Epilepsy FREE

Richard R. Babb, MD; Paul B. Eckman, MD
[+] Author Affiliations

Reprint requests to Palo Alto Medical Clinic, 300 Homer Ave, Palo Alto, Calif 94301 (Dr. Babb).


JAMA. 1972;222(1):65-66. doi:10.1001/jama.1972.03210010045009
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A common, and often perplexing, diagnostic challenge is the unfortunate person with recurrent abdominal pain. When a searching history, thorough physical examination, laboratory evaluation, and radiological studies are to no avail, such patients are often labeled neurotic, or advised to undergo exploratory surgery. It is in such a setting that the subject of abdominal epilepsy is occasionally raised. Since in our experience physicians know little about this rare entity, we feel a brief review is pertinent at this time.

Experimental studies in both animal and human subjects have shown that stimulation of certain areas in the brain stem, hypothalamus, and cerebral cortex can influence gastrointestinal activity and cause a variety of visceral sensations.1-5 Up to 20% of patients with convulsive disorders, particularly those with temporal lobe seizures, will experience a visceral aura such as epigastric distress, peculiar "rising sensations," nausea, vomiting, salivation, and borborygmi.4,6 Usually these symptoms are

REFERENCES

Hoefer PFA, Cohen SM, Greeley DMc:  Paroxysmal abdominal pain . JAMA 147:1-6, 1951;.
Glaser GH:  Visceral manifestations of epilepsy . Yale J Biol Med 30:176-186, 1957;.
O'Brien JL, Goldensohn ES:  Paroxysmal abdominal pain as a manifestation of epilepsy . Neurology 7:549-554, 1957;.
VanBuren JM:  The abdominal aura: A study of abdominal sensations occurring in epilepsy and produced by depth stimulation . Electroenceph Clin Neurophysiol 15:1-19, 1963;.
Sheehy BN, Little SC, Stone JJ:  Abdominal epilepsy . J Pediat 56:355-363, 1960;.
Mulder DW, Daly D, Bailey AA:  Visceral epilepsy . Arch Intern Med 93:481-493, 1954;.
Schubert MA, Malooly DA:  Convulsive equivalent states . Arch Intern Med 104:585-588, 1959;.
Livingston S:  Abdominal pain as a manifestation of epilepsy (abdominal epilepsy) in children . J Pediat 38:687-695, 1951;.
Schade GH, Gofman H:  Abdominal epilepsy in childhood . Pediatrics 25:151-154, 1960;.
Douglas EF, White PT:  Abdominal epilepsy—a reappraisal . J Pediat 78:59-67, 1971;.
Kellaway P, Crawley JW, Kagawa N:  A specific electroencephalographic correlate of convulsive equivalent disorders in children . J Pediat 55:582-592, 1959;.
Millichap JG, Lombroso CT, Lennox WG:  Cyclic vomiting as a form of epilepsy in children . Pediatrics 15:705-714, 1955;.
Gibbs EL, Gibbs FA:  Electroencephalographic evidence of thalamic and hypothalamic epilepsy . Neurology 1:136-144, 1951;.
Walter RD, Colbert EG, Koegler RA, et al:  A controlled study of 14- and 6-per-second EEG patterns . Arch Gen Psychiat 2:559-566, 1960;.
Lombroso CT, Schwarz IH, Clark DM, et al:  Ctenoids in healthy youths: Controlled study of 14- and 6-per-second positive spiking . Neurology 16:1152-1158, 1966;.
Prichard JS:  Abdominal pain of cerebral origin in children . Canad Med Assoc J 78:665-667, 1958;.
Farquhar BM:  Abdominal migraine in children . Brit Med J 1:1082-1085, 1956;.

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Hoefer PFA, Cohen SM, Greeley DMc:  Paroxysmal abdominal pain . JAMA 147:1-6, 1951;.
Glaser GH:  Visceral manifestations of epilepsy . Yale J Biol Med 30:176-186, 1957;.
O'Brien JL, Goldensohn ES:  Paroxysmal abdominal pain as a manifestation of epilepsy . Neurology 7:549-554, 1957;.
VanBuren JM:  The abdominal aura: A study of abdominal sensations occurring in epilepsy and produced by depth stimulation . Electroenceph Clin Neurophysiol 15:1-19, 1963;.
Sheehy BN, Little SC, Stone JJ:  Abdominal epilepsy . J Pediat 56:355-363, 1960;.
Mulder DW, Daly D, Bailey AA:  Visceral epilepsy . Arch Intern Med 93:481-493, 1954;.
Schubert MA, Malooly DA:  Convulsive equivalent states . Arch Intern Med 104:585-588, 1959;.
Livingston S:  Abdominal pain as a manifestation of epilepsy (abdominal epilepsy) in children . J Pediat 38:687-695, 1951;.
Schade GH, Gofman H:  Abdominal epilepsy in childhood . Pediatrics 25:151-154, 1960;.
Douglas EF, White PT:  Abdominal epilepsy—a reappraisal . J Pediat 78:59-67, 1971;.
Kellaway P, Crawley JW, Kagawa N:  A specific electroencephalographic correlate of convulsive equivalent disorders in children . J Pediat 55:582-592, 1959;.
Millichap JG, Lombroso CT, Lennox WG:  Cyclic vomiting as a form of epilepsy in children . Pediatrics 15:705-714, 1955;.
Gibbs EL, Gibbs FA:  Electroencephalographic evidence of thalamic and hypothalamic epilepsy . Neurology 1:136-144, 1951;.
Walter RD, Colbert EG, Koegler RA, et al:  A controlled study of 14- and 6-per-second EEG patterns . Arch Gen Psychiat 2:559-566, 1960;.
Lombroso CT, Schwarz IH, Clark DM, et al:  Ctenoids in healthy youths: Controlled study of 14- and 6-per-second positive spiking . Neurology 16:1152-1158, 1966;.
Prichard JS:  Abdominal pain of cerebral origin in children . Canad Med Assoc J 78:665-667, 1958;.
Farquhar BM:  Abdominal migraine in children . Brit Med J 1:1082-1085, 1956;.
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