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July 26, 1971, Vol 217, No. 4 >
ARTICLE | July 26, 1971

Testicular Choriocarcinoma in LSD Users: Title and subTitle BreakCoincidence or Cause? FREE

Leonard J. Levick, MD; Stanley N. Levick, MD
[+] Author Affiliations

Reprint requests to 1335 W Tabor Rd, Philadelphia 19141 (Dr. L. Levick).


JAMA. 1971;217(4):475-476. doi:10.1001/jama.1971.03190040067022
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References

Two patients with testicular choriocarcinoma had taken lysergic acid diethylamide (LSD) for from 18 to 24 months continually; each averaged over "20 trips" before the tumor developed. LSD may be a factor in causing malignant tumors.

REFERENCES

1 +
Whitmore WF Jr:  Tumors of the penis, urethra, scrotum and testis , in Campbell MR, Harrison JH (eds): Urology , ed 3. Philadelphia, WB Saunders Co, 1970;, vol 2, pp 1190-1229.
2 +
Cohen MM, Marinello MJ, Back N:  Chromosomal damage in human leukocytes induced by lysergic acid diethylamide . Science 155:1417-1419, 1967;.
3 +
Egozcue J, Irwin S, Maruffo CA:  Chromosomal damage in LSD users . JAMA 204:214-218, 1968;.
4 +
Irwin S, Egozcue J:  Chromosomal abnormalities in leukocytes from LSD-25 users . Science 157:313-314, 1967;.
5 +
Skakkebaek NE, Philip J:  LSD in mice: Abnormalities in meiotic chromosomes . Science 160:1246-1248, 1968;.
6 +
Cohen MM, Hirschhorn K, Frosch WA:  In vivo and in vitro chromosomal damage induced by LSD-25 . New Eng J Med 277:1043-1049, 1967;.
7 +
Zellweger H, McDonald JS, Abbo G:  Is lysergic acid diethylamide a teratogen? Lancet 2:1066-1068, 1967;.
8 +
Hecht F, Beals RK, Lees MH, et al:  Lysergic-acid diethylamide and cannabis as possible teratogens in man . Lancet 2:1087, 1968;.
9 +
Bender L, Siva Sankar DV:  Chromosome damage not found in leukocytes of children treated with LSD-25 . Science 159:749, 1968;.
10 +
Loughman WD, Sargent TW, Israelstam DM:  Leukocytes of humans exposed to lysergic acid diethylamide: Lack of chromosomal damage . Science 158:508-510, 1967;.
11 +
Smart RG, Bateman K:  The chromosomal and teratogenic effects of lysergic acid diethylamide: A review of the current literature . Canad Med Assoc J 99: 805-810, 1968;.
12 +
Cohen MM, Mukherjee AB:  Meiotic chromosome damage induced by LSD-25 . Nature 219:1072-1074, 1968;.
13 +
Sax K, Sax HJ:  Radiomimetic beverages, drugs and mutagens . Proc Nat Acad Sci USA 55:1431-1435, 1966;.
14 +
Bender MA:  X-ray induced chromosome aberrations in mammalian cells in vivo and in vitro , in Buzzati-Traverse A (ed): Immediate and Low Level Effects of Ionizing Radiation . London, Taylor & Francis, 1960;, pp 103-118.
15 +
Marin-Padilla M:  Histopathology of the embryonal carcinoma of the tests (embryological evaluation) . Arch Path 85:614-622, 1968;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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1 +
Whitmore WF Jr:  Tumors of the penis, urethra, scrotum and testis , in Campbell MR, Harrison JH (eds): Urology , ed 3. Philadelphia, WB Saunders Co, 1970;, vol 2, pp 1190-1229.
2 +
Cohen MM, Marinello MJ, Back N:  Chromosomal damage in human leukocytes induced by lysergic acid diethylamide . Science 155:1417-1419, 1967;.
3 +
Egozcue J, Irwin S, Maruffo CA:  Chromosomal damage in LSD users . JAMA 204:214-218, 1968;.
4 +
Irwin S, Egozcue J:  Chromosomal abnormalities in leukocytes from LSD-25 users . Science 157:313-314, 1967;.
5 +
Skakkebaek NE, Philip J:  LSD in mice: Abnormalities in meiotic chromosomes . Science 160:1246-1248, 1968;.
6 +
Cohen MM, Hirschhorn K, Frosch WA:  In vivo and in vitro chromosomal damage induced by LSD-25 . New Eng J Med 277:1043-1049, 1967;.
7 +
Zellweger H, McDonald JS, Abbo G:  Is lysergic acid diethylamide a teratogen? Lancet 2:1066-1068, 1967;.
8 +
Hecht F, Beals RK, Lees MH, et al:  Lysergic-acid diethylamide and cannabis as possible teratogens in man . Lancet 2:1087, 1968;.
9 +
Bender L, Siva Sankar DV:  Chromosome damage not found in leukocytes of children treated with LSD-25 . Science 159:749, 1968;.
10 +
Loughman WD, Sargent TW, Israelstam DM:  Leukocytes of humans exposed to lysergic acid diethylamide: Lack of chromosomal damage . Science 158:508-510, 1967;.
11 +
Smart RG, Bateman K:  The chromosomal and teratogenic effects of lysergic acid diethylamide: A review of the current literature . Canad Med Assoc J 99: 805-810, 1968;.
12 +
Cohen MM, Mukherjee AB:  Meiotic chromosome damage induced by LSD-25 . Nature 219:1072-1074, 1968;.
13 +
Sax K, Sax HJ:  Radiomimetic beverages, drugs and mutagens . Proc Nat Acad Sci USA 55:1431-1435, 1966;.
14 +
Bender MA:  X-ray induced chromosome aberrations in mammalian cells in vivo and in vitro , in Buzzati-Traverse A (ed): Immediate and Low Level Effects of Ionizing Radiation . London, Taylor & Francis, 1960;, pp 103-118.
15 +
Marin-Padilla M:  Histopathology of the embryonal carcinoma of the tests (embryological evaluation) . Arch Path 85:614-622, 1968;.

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