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ARTICLE |

Squamous Cell Carcinomas in Fanconi's Anemia FREE

Michael Swift, MD; David Zimmerman, MD; Edward R. McDonough, MD
[+] Author Affiliations

Reprint requests to New York University Medical Center, 550 First Ave, New York 10016 (Dr. Swift).


JAMA. 1971;216(2):325-326. doi:10.1001/jama.1971.03180280079018
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Squamous cell carcinomas have occurred in two more patients with Fanconi's anemia, suggesting that the gene for this syndrome predisposes the individual to solid tumors as well as leukemias.

REFERENCES

Garriga S, Crosby W H:  The incidence of leukemia in families of patients with hypoplasia of the marrow . Blood 14: 1008-1014, 1959;.
Bloom G E, Warner S, Gerald P S, Diamond L K:  Chromosome abnormalities in constitutional aplastic anemia . New Eng J Med 274:8-14, 1966;.
Swift M R, Hirschhorn K:  Fanconi's anemia: inherited susceptibility to chromosome breakage in various tissues . Ann Intern Med 65:496-503, 1966;.
Esparza A, Thompson W R:  Familial hypoplastic anemia with multiple congenital anomalies (Fanconi's syndrome)— report of three cases . Rhode Island Med J 49:103-110, 1966;.
 Clincopathologic Conference: Fanconi's anemia hepatic cirrhosis . Amer J Med 39:464-475, 1965;.
Cowdell R H, Phizackerley P J R, Pyke D A:  Constitutional anemia (Fanconi's syndrome) and leukemia in two brothers . Blood 10:788-801, 1955;.
Silver H K, Blair W C, Kempe C H:  Fanconi's syndrome; multiple congenital anomalies with hypoplastic anemia . Amer J Dis Child 83:14-25, 1952;.
Baumann T:  Konstitutionelle Panmyelopathise mit multiplen Abartungen (Fanconi syndrome) . Ann Paediat 177:65, 1951;.
Bernard J, Mathe G, Najean Y:  Contribution a l'etude clinique et physiopathologique da la maladie de Fanconi . Rev franc etudes clin et biol 3:599-611, 1958;.
Todaro G J, Green H, Swift M R:  Susceptibility of human diploid fibroblast strains to transformation by SV40 virus . Science 153:1252-1254, 1966;.

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Garriga S, Crosby W H:  The incidence of leukemia in families of patients with hypoplasia of the marrow . Blood 14: 1008-1014, 1959;.
Bloom G E, Warner S, Gerald P S, Diamond L K:  Chromosome abnormalities in constitutional aplastic anemia . New Eng J Med 274:8-14, 1966;.
Swift M R, Hirschhorn K:  Fanconi's anemia: inherited susceptibility to chromosome breakage in various tissues . Ann Intern Med 65:496-503, 1966;.
Esparza A, Thompson W R:  Familial hypoplastic anemia with multiple congenital anomalies (Fanconi's syndrome)— report of three cases . Rhode Island Med J 49:103-110, 1966;.
 Clincopathologic Conference: Fanconi's anemia hepatic cirrhosis . Amer J Med 39:464-475, 1965;.
Cowdell R H, Phizackerley P J R, Pyke D A:  Constitutional anemia (Fanconi's syndrome) and leukemia in two brothers . Blood 10:788-801, 1955;.
Silver H K, Blair W C, Kempe C H:  Fanconi's syndrome; multiple congenital anomalies with hypoplastic anemia . Amer J Dis Child 83:14-25, 1952;.
Baumann T:  Konstitutionelle Panmyelopathise mit multiplen Abartungen (Fanconi syndrome) . Ann Paediat 177:65, 1951;.
Bernard J, Mathe G, Najean Y:  Contribution a l'etude clinique et physiopathologique da la maladie de Fanconi . Rev franc etudes clin et biol 3:599-611, 1958;.
Todaro G J, Green H, Swift M R:  Susceptibility of human diploid fibroblast strains to transformation by SV40 virus . Science 153:1252-1254, 1966;.
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