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Acute Septicemic Melioidosis: Title and subTitle BreakSuccessful Treatment With Gentamicin FREE

LCDR Jack E. Zimmerman, MC
[+] Author Affiliations

The opinions or assertions contained herein do not necessarily reflect the views of the Bureau of Medicine and Surgery of the Navy Department or the naval service at large.

Reprint requests to National Naval Medical Center, Bethesda, Md 20015 (LCDR Zimmerman).


JAMA. 1970;213(13):2266-2267. doi:10.1001/jama.1970.03170390056015
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The acute septicemic form of melioidosis is associated with a high mortality despite currently recommended antibiotic therapy. A patient who developed multiple complications of wounds received in Vietnam, including Pseudomonas pseudomallei septicemia, was successfully treated with gentamicin sulfate. The use of this drug in the treatment of melioidosis has not been previously reported. Gentamicin may be useful in the treatment of this disease.

REFERENCES

Sheehy TW, Deller JJ, Weber DR:  Melioidosis . Ann Intern Med 67:897-900, 1967;.
Duong-Hong-Mo, Trin-Heip-Cuong:  A typical case of melioidosis in South Vietnam . Milit Med 132:90-100, 1967;.
Chin W: Melioidosis. USARV Med Bull 1:13-19, 1966;.
Flemma RJ, DiVineenti FC, Dotin LN, et al:  Pulmonary melioidosis . Ann Thorac Surg 7:191-199, 1969;.
Spotnitz M, Rudnitzky J, Rambaud JJ:  Melioidosis pneumonitis . JAMA 202: 950-954, 1967;.
Weber DR:  Acute varieties of melioidosis occurring in U.S. soldiers in Vietnam . Amer J Med 46:234-244, 1969;.
Patterson MC, Darling CL, Blumenthal JB:  Acute melioidosis in a soldier home from South Vietnam. JAMA 200: 447-451, 1967;.
Brundage WG, Thuss CJ, Walden DC:  Four fatal cases of melioidosis in U.S. soldiers in Vietnam . Amer J Trop Med Hyg 17:183-191, 1968;.
Magee HR, Mitchell MB, Fitzwater JJ, et al:  Melioidosis . Med J Aust 1:1180-1183, 1967;.
Baumann BB, Morita ET:  Systemic melioidosis presenting as myocardial infarct . Ann Intern Med 67:836-842, 1967;.
Washington JA, Ritts RE,  Martin WJ: In vitro susceptibility of gram-negative bacilli to gentamicin . Mayo Clin Proc 45:146-149, 1970;.

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Sheehy TW, Deller JJ, Weber DR:  Melioidosis . Ann Intern Med 67:897-900, 1967;.
Duong-Hong-Mo, Trin-Heip-Cuong:  A typical case of melioidosis in South Vietnam . Milit Med 132:90-100, 1967;.
Chin W: Melioidosis. USARV Med Bull 1:13-19, 1966;.
Flemma RJ, DiVineenti FC, Dotin LN, et al:  Pulmonary melioidosis . Ann Thorac Surg 7:191-199, 1969;.
Spotnitz M, Rudnitzky J, Rambaud JJ:  Melioidosis pneumonitis . JAMA 202: 950-954, 1967;.
Weber DR:  Acute varieties of melioidosis occurring in U.S. soldiers in Vietnam . Amer J Med 46:234-244, 1969;.
Patterson MC, Darling CL, Blumenthal JB:  Acute melioidosis in a soldier home from South Vietnam. JAMA 200: 447-451, 1967;.
Brundage WG, Thuss CJ, Walden DC:  Four fatal cases of melioidosis in U.S. soldiers in Vietnam . Amer J Trop Med Hyg 17:183-191, 1968;.
Magee HR, Mitchell MB, Fitzwater JJ, et al:  Melioidosis . Med J Aust 1:1180-1183, 1967;.
Baumann BB, Morita ET:  Systemic melioidosis presenting as myocardial infarct . Ann Intern Med 67:836-842, 1967;.
Washington JA, Ritts RE,  Martin WJ: In vitro susceptibility of gram-negative bacilli to gentamicin . Mayo Clin Proc 45:146-149, 1970;.
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