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ARTICLE |

Homologous Serum Hepatitis—A True Experience FREE

Martel J. Dailey, MD
JAMA. 1970;212(5):881-882. doi:10.1001/jama.1970.03170180157030
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To the Editor.—  The homologous serum hepatitis (HSH) virus has many curious characteristics but the most striking feature of the virus is its ability to produce disease like a phantom. If the HSH virus causes hepatitis, by intrahepatic replication, then why can't we recover the virus from the liver? The yellow fever virus and the HSH virus are the same size1 yet the yellow fever virus did not remain elusive. Yellow fever succumbed to medical research several decades ago.The HSH virus is transmitted primarily by parenteral inoculation2 yet the virus had worldwide distribution with the advent of parenteral inoculation. How did the virus achieve worldwide distribution? Why should nature impose such a restrictive means of transmittal for this virus?Two explanations are usually offered to explain the natural reservoir of the virus. The first proposes that there existed a maternal carrier state. The maternal carrier infected her

REFERENCES

Rhodes, Van Rooyen: A Textbook of Virology , ed 4. Baltimore, Williams & Wilkins Co, 1962;.
Scheinberg H, Kinney TD, Janeway CA:  Homologous serum jaundice . JAMA 134:841-848, 1947;.
Okochi K, Murakami S:  Observations on Australia antigen in Japanese . Vox Sang 15:374-385, 1968;.
Stampfli:  Fatal posttransfusional hepatitis in Switzerland . Minn Med 52:53-61, 1969;.
 Hepatitis virus and renal dialysis , editorial. Lancet 2:989-990, 1969;.
Conn HF: Current Therapy , Philadelphia, WB Saunders Co, 1969;.
Zuckerman AJ:  Virus hepatitis after blood transfusion . Brit J Clin Pract 23:9-10, 1969;.
 War on serum hepatitis continues on two fronts, MEDICAL NEWS . JAMA 210:2001-2003, 1969;.
Oldstone MBA, Dixon F:  Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection , J Exp Med 129:483-506, 1969;.
Hughes TP:  A precipitin reaction in yellow fever . J Immunol 25:275-294, 1933;.
Eaton MD, Murphy WD, Hanford VL:  Heterogenetic antibodies in acute hepatitis , J Exp Med 79:539-557, 1944;.
Morbidity and Mortality . US Dept Health Education and Welfare, 1970;.
Blumberg BS, Sutnick AI, London WT:  Hepatitis and leukemia: Their relation to Australia antigen . Bull NY Acad Med 44:1566-1586, 1968;.
Danks D, Bodian MA:  Genetic study of neonatal obstructive jaundice . Arch Dis Child 38:378, 1963;.
 Genesis of hepatitis , editorial. New Eng J Med 281:1190, 1969;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Rhodes, Van Rooyen: A Textbook of Virology , ed 4. Baltimore, Williams & Wilkins Co, 1962;.
Scheinberg H, Kinney TD, Janeway CA:  Homologous serum jaundice . JAMA 134:841-848, 1947;.
Okochi K, Murakami S:  Observations on Australia antigen in Japanese . Vox Sang 15:374-385, 1968;.
Stampfli:  Fatal posttransfusional hepatitis in Switzerland . Minn Med 52:53-61, 1969;.
 Hepatitis virus and renal dialysis , editorial. Lancet 2:989-990, 1969;.
Conn HF: Current Therapy , Philadelphia, WB Saunders Co, 1969;.
Zuckerman AJ:  Virus hepatitis after blood transfusion . Brit J Clin Pract 23:9-10, 1969;.
 War on serum hepatitis continues on two fronts, MEDICAL NEWS . JAMA 210:2001-2003, 1969;.
Oldstone MBA, Dixon F:  Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection , J Exp Med 129:483-506, 1969;.
Hughes TP:  A precipitin reaction in yellow fever . J Immunol 25:275-294, 1933;.
Eaton MD, Murphy WD, Hanford VL:  Heterogenetic antibodies in acute hepatitis , J Exp Med 79:539-557, 1944;.
Morbidity and Mortality . US Dept Health Education and Welfare, 1970;.
Blumberg BS, Sutnick AI, London WT:  Hepatitis and leukemia: Their relation to Australia antigen . Bull NY Acad Med 44:1566-1586, 1968;.
Danks D, Bodian MA:  Genetic study of neonatal obstructive jaundice . Arch Dis Child 38:378, 1963;.
 Genesis of hepatitis , editorial. New Eng J Med 281:1190, 1969;.
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