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April 13, 1970, Vol 212, No. 2 >
ARTICLE | April 13, 1970

Central Venous Oxygen Saturations: Title and subTitle BreakValue of Serial Determinations in Patients With Acute Myocardial Infarction FREE

Adolph M. Hutter, Jr., MD; Arthur J. Moss, MD
[+] Author Affiliations

Reprint requests to 260 Crittenden Blvd, Rochester, NY (Dr. Moss).


JAMA. 1970;212(2):299-303. doi:10.1001/jama.1970.03170150053009
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References

The clinical significance of serial central venous oxygen saturation (CVSo ) determinations was investigated in 34 patients with acute myocardial infarction. The mean initial CVSo2 of 73% fell to a low of 68% (P<0.05) on the third postinfarction day, and rose slightly thereafter. The average values of the lowest recorded CVSo2 in 9 patients with an uncomplicated course, 10 patients with a moderately complicated course, and 15 patients with a severely complicated clinical course were 65%, 65%, and 54%, respectively. A fall in CVSo2 to less than 55% preceded the development of hypotension in three patients and was concurrent with hypotension in two. Serial CVSo2 determinations are useful in the early detection of cardiac decompensation in patients with acute myocardial infarction.

REFERENCES

1 +
Lown B, Fakhro AM, Hood WB Jr, et al:  The coronary care unit: New perspectives and directions . JAMA 199:188-198, 1967;.
2 +
Proceedings of the National Conference on Coronary Care Units , publication 1764. Public Health Service, 1968;.
3 +
Murphy GW, Glick G, Schreiner BF, et al:  Cardiac output in acute myocardial infarction . Amer J Cardiol 11:587-593, 1963;.
4 +
Freis ED, Schnaper HW, Johnson RL, et al:  Hemodynamic alterations in acute myocardial infarction . J Clin Invest 31:131140, 1952;.
5 +
Viancos JG, Secher PH, Keats AS, et al:  Internal jugular venous oxygen tensions as an index of cerebral blood flow during carotid endarterectomy . Circulation 34:875-882, 1966;.
6 +
Moss AJ, Vittands I, Schenk EA:  Cardiovascular effects of sustained norepinephrine infusions: I. Hemodynamics . Circ Res 18:596-604, 1966;.
7 +
MacKenzie GJ, Flenley DC, Taylor SH, et al:  Circulatory and respiratory studies in myocardial infarction and cardiogenic shock . Lancet 2:825-832, 1964;.
8 +
Burch GI,  DePasquale NP: The hematocrit in patients with myocardial infarction . JAMA 180:63-65, 1962;.
9 +
Conley CL, Russell RP, Thomas CB, et al:  Hematocrit values in coronary artery disease . Arch Intern Med 113:170-176, 1964;.
10 +
Sedziwy L, Thomas M, Shillingford J:  Some observations on hematocrit changes with acute myocardial infarction . Brit Heart J 30:344-349, 1968;.
11 +
Scheinman MM, Brown MA, Rapaport E:  Critical assessment of use of central venous oxygen saturation as a mirror of mixed venous oxygen in severely ill cardiac patients . Circulation 40:165-169, 1969;.
12 +
Goldman RH, Braniff B, Harrison DC, et al:  The use of central venous oxygen saturation measurements in a coronary care unit . Ann Intern Med 68:1280-1287, 1968;.

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1 +
Lown B, Fakhro AM, Hood WB Jr, et al:  The coronary care unit: New perspectives and directions . JAMA 199:188-198, 1967;.
2 +
Proceedings of the National Conference on Coronary Care Units , publication 1764. Public Health Service, 1968;.
3 +
Murphy GW, Glick G, Schreiner BF, et al:  Cardiac output in acute myocardial infarction . Amer J Cardiol 11:587-593, 1963;.
4 +
Freis ED, Schnaper HW, Johnson RL, et al:  Hemodynamic alterations in acute myocardial infarction . J Clin Invest 31:131140, 1952;.
5 +
Viancos JG, Secher PH, Keats AS, et al:  Internal jugular venous oxygen tensions as an index of cerebral blood flow during carotid endarterectomy . Circulation 34:875-882, 1966;.
6 +
Moss AJ, Vittands I, Schenk EA:  Cardiovascular effects of sustained norepinephrine infusions: I. Hemodynamics . Circ Res 18:596-604, 1966;.
7 +
MacKenzie GJ, Flenley DC, Taylor SH, et al:  Circulatory and respiratory studies in myocardial infarction and cardiogenic shock . Lancet 2:825-832, 1964;.
8 +
Burch GI,  DePasquale NP: The hematocrit in patients with myocardial infarction . JAMA 180:63-65, 1962;.
9 +
Conley CL, Russell RP, Thomas CB, et al:  Hematocrit values in coronary artery disease . Arch Intern Med 113:170-176, 1964;.
10 +
Sedziwy L, Thomas M, Shillingford J:  Some observations on hematocrit changes with acute myocardial infarction . Brit Heart J 30:344-349, 1968;.
11 +
Scheinman MM, Brown MA, Rapaport E:  Critical assessment of use of central venous oxygen saturation as a mirror of mixed venous oxygen in severely ill cardiac patients . Circulation 40:165-169, 1969;.
12 +
Goldman RH, Braniff B, Harrison DC, et al:  The use of central venous oxygen saturation measurements in a coronary care unit . Ann Intern Med 68:1280-1287, 1968;.

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