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New Concepts Relating to the Preexcitation Syndrome FREE

M. Irené Ferrer, MD
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JAMA. 1967;201(13):1038-1039. doi:10.1001/jama.1967.03130130064015
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Since its original description in 1930, considerable controversy has centered on the basic explanation for the anomalous atrioventricular (AV) conduction seen in the preexcitation or Wolff-Parkinson-White (WPW) syndrome.1 An abnormally short PR interval associated with a prolonged QRS containing a delta wave (an initial slurring or thickening of the first wave of the QRS complex, be this an R or an S) in the presence of sinus rhythm is the classic criteria for its electrocardiographic diagnosis.2 The delta wave represents the early excitation of the ventricles. However, in addition to this form of anomalous AV conduction, several variants have come to be recognized.3-5 These include a short PR interval (less than 0.12 seconds) with a normal QRS, ie, a QRS with normal duration and no delta wave and a normal or even prolonged PR interval coupled to a prolonged QRS containing a delta wave. Recent and very

REFERENCES

Wolff L.; Parkinson, J.; and White, P.D.:  Bundle Branch Block With Short PR Interval in Healthy Young People Prone to Paroxysmal Tachycardia , Amer Heart J 5:685-704 ( (Aug) ) 1930;.
Bellet, S.: Clinical Disorders of the Heart Beat , ed 2, Philadelphia: Lea & Febiger, 1963;.
Friedberg, C.K.: Diseases of the Heart , ed 3, Philadelphia: W.B. Saunders Co., 1966;, p 631.
Fox, T.T.:  Aberrant Atrio-Ventricular Conduction in a Case Showing a Short PR Interval and an Abnormal but Not Prolonged QRS Complex , Amer J Med Sci 209:199-203 ( (Feb) ) 1945;.
Borduas, J.L., et al:  Studies on the Mechanism of Ventricular Activity: XIV. Clinical and Experimental Studies of Accelerated Auricula-Ventricular Conduction , Circulation 11:69-88 ( (Jan) ) 1955;.
Lev, M.: "The Pre-Excitation Syndrome: Anatomic Considerations of Anomalous A-V Pathways," in Dreifus, L.S., and Koff, W.S. (eds.): Mechanisms and Therapy of Cardiac Arrhythmias , New York: Grune & Stratton, Inc., 1966;, pp 665-670.
James, T.N.: "Identification of the Supraventricular Arrhythmias: The Specialized Conducting Tissue of the Atria," in Dreifus, L.S., and Koff, W.C. (eds.): Mechanisms and Therapy of Cardiac Arrhythmias , New York: Grune & Stratton, 1966;, pp 97-106.
Prinzmetal, M., et al: Accelerated Conduction: The Wolff-Parkinson-White Syndrome and Related Conditions , New York: Grune & Stratton, 1952;.
James, T.N.:  Morphology of the Human Atrioventricular Node: With Remarks Pertinent to Its Electrophysiology , Amer Heart J 62:756-771 ( (Dec) ) 1961;.
Mahaim, I., and Benatt, A.:  Nouvelles Recherches sur les Connexions Superieures de la Branche Gauche du Faisceau de His-Tawara avec la Cloison Interventriculaire , Cardiologia 1:61-73, 1937;.
Lev, M., et al:  Anatomic Findings in a Case of Ventricular Pre-Excitation (W-P-W) Terminating in Complete Atrioventricular Block , Circulation 34:718-733 ( (Nov) ) 1966;.
Sherf, L., and James, T.N.:  A New Look at Some Old Questions in Clinical Electrocardiography , Henry Ford Hosp Med Bull 14:265-308 ( (Sept) ) 1966;.
Harnischfeger, W.W.:  Hereditary Occurrence of the Pre-Excitation (W-P-W) Syndrome With Re-entry Mechanism and Concealed Conduction , Circulation 19:28-40 ( (Jan) ) 1959;.

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Wolff L.; Parkinson, J.; and White, P.D.:  Bundle Branch Block With Short PR Interval in Healthy Young People Prone to Paroxysmal Tachycardia , Amer Heart J 5:685-704 ( (Aug) ) 1930;.
Bellet, S.: Clinical Disorders of the Heart Beat , ed 2, Philadelphia: Lea & Febiger, 1963;.
Friedberg, C.K.: Diseases of the Heart , ed 3, Philadelphia: W.B. Saunders Co., 1966;, p 631.
Fox, T.T.:  Aberrant Atrio-Ventricular Conduction in a Case Showing a Short PR Interval and an Abnormal but Not Prolonged QRS Complex , Amer J Med Sci 209:199-203 ( (Feb) ) 1945;.
Borduas, J.L., et al:  Studies on the Mechanism of Ventricular Activity: XIV. Clinical and Experimental Studies of Accelerated Auricula-Ventricular Conduction , Circulation 11:69-88 ( (Jan) ) 1955;.
Lev, M.: "The Pre-Excitation Syndrome: Anatomic Considerations of Anomalous A-V Pathways," in Dreifus, L.S., and Koff, W.S. (eds.): Mechanisms and Therapy of Cardiac Arrhythmias , New York: Grune & Stratton, Inc., 1966;, pp 665-670.
James, T.N.: "Identification of the Supraventricular Arrhythmias: The Specialized Conducting Tissue of the Atria," in Dreifus, L.S., and Koff, W.C. (eds.): Mechanisms and Therapy of Cardiac Arrhythmias , New York: Grune & Stratton, 1966;, pp 97-106.
Prinzmetal, M., et al: Accelerated Conduction: The Wolff-Parkinson-White Syndrome and Related Conditions , New York: Grune & Stratton, 1952;.
James, T.N.:  Morphology of the Human Atrioventricular Node: With Remarks Pertinent to Its Electrophysiology , Amer Heart J 62:756-771 ( (Dec) ) 1961;.
Mahaim, I., and Benatt, A.:  Nouvelles Recherches sur les Connexions Superieures de la Branche Gauche du Faisceau de His-Tawara avec la Cloison Interventriculaire , Cardiologia 1:61-73, 1937;.
Lev, M., et al:  Anatomic Findings in a Case of Ventricular Pre-Excitation (W-P-W) Terminating in Complete Atrioventricular Block , Circulation 34:718-733 ( (Nov) ) 1966;.
Sherf, L., and James, T.N.:  A New Look at Some Old Questions in Clinical Electrocardiography , Henry Ford Hosp Med Bull 14:265-308 ( (Sept) ) 1966;.
Harnischfeger, W.W.:  Hereditary Occurrence of the Pre-Excitation (W-P-W) Syndrome With Re-entry Mechanism and Concealed Conduction , Circulation 19:28-40 ( (Jan) ) 1959;.
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