0
February 20, 1967, Vol 199, No. 8 >
ARTICLE | February 20, 1967

Nuclear Studies in Human Pituitary Glands of Varying Weights FREE

Sally B. Fand, MD; Carl W. Ehmann; Anthony J. Buscaglia; Luigi Messineo, PhD
[+] Author Affiliations

Read before the session on metabolism and renal diseases of the Sixth Multidiscipline Research Forum during the 115th annual convention of the American Medical Association, Chicago, June 29, 1966.

Reprint requests to 3495 Bailey Ave, Buffalo 14215 (Dr. Fand).


From the Histochemical Research Laboratory, Veterans Administration Hospital and School of Medicine, State University of New York, Buffalo. Mr. Ehmann is now a senior medical student at the State University of New York. Mr. Buscaglia is now a freshman medical student at Creighton University, Omaha.


JAMA. 1967;199(8):563-566. doi:10.1001/jama.1967.03120080097017
Text Size: A A A
Published online
Article
References

The endocrine glands react to demands for increased hormone production by an increase in their functional size and their weight. Thus, the thyroid, the adrenal, and the parathyroid glands are known to enlarge demonstrably in the syndromes associated with their increased hormone production. The pituitary, too, is generally considered to react in this manner, and increased pituitary size has been reported, for example, in primary myxedema and following adrenalectomy for Cushing's syndrome: in both instances there is presumably a compensatory increase in tropic hormone output by the pituitary—thyroid stimulating hormone in the first, adrenocorticotrophic hormone in the second. Evidence of a correlation between decreasing size and reduced hormone output can be seen in steroid-treated patients where a diminution in pituitary size—associated with decreased tropic hormone release—may well be the rule.

These examples of reactive changes in pituitary size and weight in the human could be challenged; pituitary size increase in

REFERENCES

1 +
Statland, H., and Lerman, J.:  The Function of the Adrenal Cortex in Myxedema With Some Observations on Pituitary Function , J Clin Endocr 10:1401-1416 ( (Nov) ) 1950;.
2 +
Salassa, R.M., et al:  Pituitary Tumors in Patients With Cushing's Syndrome , J Clin Endocr 19:1523-1539 ( (Dec) ) 1959;.
3 +
Simpson, W.L.:  An Experimental Analysis of the Altmann Technic of Freezing-Drying , Anat Rec 80:173-189 ( (June 25) ) 1941;.
4 +
Decosse, J.J., and Aiello, N.:  Fuelgen Hydrolysis: Effect of Acid and Temperature , J Histochem Cytochem 14:601-604 ( (Aug) ) 1966;.
5 +
Lillie, R.D.: Histopathologic Technic and Practical Histochemistry , New York: Blakiston Co., 1954;, p 156.
6 +
Deeley, E.M.:  An Integrating Microdensitometer for Biological Cells , J Sci Instrum 32:263-267 ( (July) ) 1955;.
7 +
Davidson, J.N.: The Biochemistry of the Nucleic Acids , New York: Methuen & Co., Ltd., 1957;, pp 82-83.
8 +
Dische, Z.: " Color Reactions of Nucleic Acid Components ," in Chargaff, E. and Davidson, J.N. (eds.): The Nucleic Acids: Chemistry and Biology , New York: Academic Press, Inc., 1955;, vol 1.
9 +
Fand, S.B., and Spencer, R.P.:  Off-Peak Absorption Measurements in Feulgen Cytophotometry , J Cell Biol 22:515-520 ( (Sept) ) 1964;.
10 +
Millhouse, E.W., Jr.:  Microspectrophotometric Measurements of Deoxyribonucleic Acid in Feulgen-Stained Nuclei of the Anterior Pituitary Cells , J Histochem Cytochem 9:661-669 ( (Nov) ) 1961;.
11 +
Faund, S.B.; Hale, A.J.; and Currie, A.R.: " The Distribution of DNA in the Human Pituitary Gland," in Proceedings of the 103rd Meeting of the Pathology Society of Great Britain, July, 1961 , J Path and Bact 82:561 ( (July) ) 1961;.
12 +
Daughaday, W.H.: " The Adenohypophysis ," in Williams, R.H. (ed.): Textbook of Endocrinology , Philadelphia: W. B. Saunders Co., 1962;, pp 14-17.
13 +
Rasmussen, A.T.:  The Weight of the Principal Components of the Normal Hypophysis Cerebri of the Adult Human Female , Amer J Anat 55:253-275 ( (Sept) ) 1934;.
14 +
Floderus, S.:  Changes in the Human Hypophysis in Connection With Pregnancy , Acta Anat 8:329-346, 1949;.
15 +
Sheehan, H.L.:  The Repair of Post-Partum Necrosis of the Anterior Lobe of the Pituitary Gland , Acta Endocr 48:40-60 ( (Jan) ) 1965;.
16 +
Goss, R.J.:  Hypertrophy Versus Hyperplasia , Science 153: 1615-1620 ( (Sept 30) ) 1966;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Statland, H., and Lerman, J.:  The Function of the Adrenal Cortex in Myxedema With Some Observations on Pituitary Function , J Clin Endocr 10:1401-1416 ( (Nov) ) 1950;.
2 +
Salassa, R.M., et al:  Pituitary Tumors in Patients With Cushing's Syndrome , J Clin Endocr 19:1523-1539 ( (Dec) ) 1959;.
3 +
Simpson, W.L.:  An Experimental Analysis of the Altmann Technic of Freezing-Drying , Anat Rec 80:173-189 ( (June 25) ) 1941;.
4 +
Decosse, J.J., and Aiello, N.:  Fuelgen Hydrolysis: Effect of Acid and Temperature , J Histochem Cytochem 14:601-604 ( (Aug) ) 1966;.
5 +
Lillie, R.D.: Histopathologic Technic and Practical Histochemistry , New York: Blakiston Co., 1954;, p 156.
6 +
Deeley, E.M.:  An Integrating Microdensitometer for Biological Cells , J Sci Instrum 32:263-267 ( (July) ) 1955;.
7 +
Davidson, J.N.: The Biochemistry of the Nucleic Acids , New York: Methuen & Co., Ltd., 1957;, pp 82-83.
8 +
Dische, Z.: " Color Reactions of Nucleic Acid Components ," in Chargaff, E. and Davidson, J.N. (eds.): The Nucleic Acids: Chemistry and Biology , New York: Academic Press, Inc., 1955;, vol 1.
9 +
Fand, S.B., and Spencer, R.P.:  Off-Peak Absorption Measurements in Feulgen Cytophotometry , J Cell Biol 22:515-520 ( (Sept) ) 1964;.
10 +
Millhouse, E.W., Jr.:  Microspectrophotometric Measurements of Deoxyribonucleic Acid in Feulgen-Stained Nuclei of the Anterior Pituitary Cells , J Histochem Cytochem 9:661-669 ( (Nov) ) 1961;.
11 +
Faund, S.B.; Hale, A.J.; and Currie, A.R.: " The Distribution of DNA in the Human Pituitary Gland," in Proceedings of the 103rd Meeting of the Pathology Society of Great Britain, July, 1961 , J Path and Bact 82:561 ( (July) ) 1961;.
12 +
Daughaday, W.H.: " The Adenohypophysis ," in Williams, R.H. (ed.): Textbook of Endocrinology , Philadelphia: W. B. Saunders Co., 1962;, pp 14-17.
13 +
Rasmussen, A.T.:  The Weight of the Principal Components of the Normal Hypophysis Cerebri of the Adult Human Female , Amer J Anat 55:253-275 ( (Sept) ) 1934;.
14 +
Floderus, S.:  Changes in the Human Hypophysis in Connection With Pregnancy , Acta Anat 8:329-346, 1949;.
15 +
Sheehan, H.L.:  The Repair of Post-Partum Necrosis of the Anterior Lobe of the Pituitary Gland , Acta Endocr 48:40-60 ( (Jan) ) 1965;.
16 +
Goss, R.J.:  Hypertrophy Versus Hyperplasia , Science 153: 1615-1620 ( (Sept 30) ) 1966;.

Letters

Submit a Letter
CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2012 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems