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ARTICLE |

Burkitt's Lymphoma in an Arid Part of Texas FREE

Capt Jeremiah J. Twomey, MC
[+] Author Affiliations

Reprint requests to Box 607, William Beaumont General Hospital, El Paso, Tex.


USA

From the Department of Medicine, William Beaumont General Hospital, El Paso, Tex.


JAMA. 1966;198(10):1124-1125. doi:10.1001/jama.1966.03110230140041
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BURKITT, in 1958, drew attention to the high incidence of an unusual type of lymphoma in Uganda.1 It occurs largely in children and involves the retroperitoneal space, facial bones, and ovaries in females.2 The peripheral lymph nodes are usually spared. These lymphomas are uniformly immature lymphoreticular tumors with prominent histiocytic phagocytosis giving a characteristic microscopic "starry sky" appearance.3 This histiocytic phagocytosis is not restricted to the Burkitt type of lymphoma,4 which is best recognized by its anatomical distribution.

The epidemiology of Burkitt's tumor in Africa5,6 suggests that its incidence is influenced by environmental factors. These include a warm climate throughout the year5 and a heavy annual rainfall.6 Cases have been observed only occasionally at altitudes higher than 5,000 feet.6,7 This may be related to lower prevailing temperatures at higher altitudes. Its geographical distribution has been suggested as evidence that the tumor may be

REFERENCES

Burkitt, D.:  Sarcoma Involving Jaws in African Children , Brit J Surg 46:218-223 ( (Nov) ) 1958;.
Burkitt, D., and O'Connor, G.T.:  Malignant Lymphoma in African Children , Cancer 14:258-269 ( (March) -April) 1961;.
Wright, D.:  Cytology and Histochemistry of the Burkitt Lymphoma , Brit J Cancer 17:50-55 ( (March) ) 1963;.
O'Connor, G.T.; Rappaport, H.; and Smith, E.B.:  Childhood Lymphoma Resembling "Burkitt's Tumor" in the United States , Cancer 18:411-417 ( (April) ) 1965;.
Burkitt, D.:  A Children's Cancer Dependent on Climatic Factors , Nature 194:232-234 ( (April 21) ) 1962;.
Burkitt, D., and Wright, D.:  Geographical and Tribal Distribution of the African Lymphoma in Uganda , Brit Med J 1:569-573 ( (March 5) ) 1966;.
Gluckman, J.:  Multifocal Lymphoma in South Africa: First Observation in South Africa and in White Children , S Afr Bull Cancer 7:7-12 ( (Jan) -March) 1963;.
Epstein, M.A., et al:  Morphologic and Biological Studies on a Virus in Cultured Lymphoblasts From Burkitt's Lymphoma , J Exp Med 121:761-770 ( (May) ) 1965;.
Toplin, I., and Schidlovsky, G.:  Partial Purification and Electron Microscopy of Virus in the EB-3 Cell Line Derived From a Burkitt Lymphoma , Science 152:1084-1085 ( (May 20) ) 1966;.
Beltran, G.; Baez, A.; and Correa, P.:  Burkitt's Lymphoma in Colombia , Amer J Med 40:211-216 ( (Feb) ) 1966;.
Dorfman, R.F.:  Childhood Lymphosarcoma in St. Louis, Missouri, Clinically and Histologically Resembling Burkitt's Tumor , Cancer 18:418-429 ( (April) ) 1965;.
Dalldorf, G.:  Lymphomas in African Children , JAMA 181: 1026-1028 ( (Feb 16) ) 1962;.
Rosenberg, S.A., et al:  Lymphosarcoma in Children , New Eng J Med 259:505-512 ( (Sept 11) ) 1958;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Burkitt, D.:  Sarcoma Involving Jaws in African Children , Brit J Surg 46:218-223 ( (Nov) ) 1958;.
Burkitt, D., and O'Connor, G.T.:  Malignant Lymphoma in African Children , Cancer 14:258-269 ( (March) -April) 1961;.
Wright, D.:  Cytology and Histochemistry of the Burkitt Lymphoma , Brit J Cancer 17:50-55 ( (March) ) 1963;.
O'Connor, G.T.; Rappaport, H.; and Smith, E.B.:  Childhood Lymphoma Resembling "Burkitt's Tumor" in the United States , Cancer 18:411-417 ( (April) ) 1965;.
Burkitt, D.:  A Children's Cancer Dependent on Climatic Factors , Nature 194:232-234 ( (April 21) ) 1962;.
Burkitt, D., and Wright, D.:  Geographical and Tribal Distribution of the African Lymphoma in Uganda , Brit Med J 1:569-573 ( (March 5) ) 1966;.
Gluckman, J.:  Multifocal Lymphoma in South Africa: First Observation in South Africa and in White Children , S Afr Bull Cancer 7:7-12 ( (Jan) -March) 1963;.
Epstein, M.A., et al:  Morphologic and Biological Studies on a Virus in Cultured Lymphoblasts From Burkitt's Lymphoma , J Exp Med 121:761-770 ( (May) ) 1965;.
Toplin, I., and Schidlovsky, G.:  Partial Purification and Electron Microscopy of Virus in the EB-3 Cell Line Derived From a Burkitt Lymphoma , Science 152:1084-1085 ( (May 20) ) 1966;.
Beltran, G.; Baez, A.; and Correa, P.:  Burkitt's Lymphoma in Colombia , Amer J Med 40:211-216 ( (Feb) ) 1966;.
Dorfman, R.F.:  Childhood Lymphosarcoma in St. Louis, Missouri, Clinically and Histologically Resembling Burkitt's Tumor , Cancer 18:418-429 ( (April) ) 1965;.
Dalldorf, G.:  Lymphomas in African Children , JAMA 181: 1026-1028 ( (Feb 16) ) 1962;.
Rosenberg, S.A., et al:  Lymphosarcoma in Children , New Eng J Med 259:505-512 ( (Sept 11) ) 1958;.
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