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ARTICLE |

Infection of Knee Joint by Mycobacterium kansasii FREE

Melvin C. Godwin, MD
[+] Author Affiliations

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From the Department of Pathology, St. Mary of Nazareth Hospital, Chicago.


JAMA. 1965;194(1):88-89. doi:10.1001/jama.1965.03090140096029
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EXTRAPULMONARY infections caused by unclassified acid-fast mycobacteria of Runyon group I photochromogenic type without accompanying pulmonary disease have been rarely reported. It is generally accepted that two of the Runyon groups' of atypical mycobacteria are capable of producing progressive disease. One is group I, photochromogenic Mycobacterium kansasii. This group is characterized by colonial pigmentation following purposeful exposure of the culture to light. These microorganisms often possess a natural resistance to the major antituberculous drugs in low concentration. Experience with in vitro drugsensitivity testing has taught the need for initially higher doses of drugs, particularly isoniazid (INH). It is with this well-defined group of mycobacteria that the present case is identified.

Group III, nonchromogenic Battey strain of atypical mycobacteria, produces indolent disease that is difficult, if at all possible, to reproduce in laboratory animals. It possesses natural resistance to low concentrations of antituberculous drugs. It is easily differentiated from M tuberculosis

REFERENCES

Runyon, E.H.:  Anonymous Mycobacteria in Pulmonary Disease , Med Clin N Amer 43:273-290 ( (Jan) ) 1959;.
Slooff, J.P.:  Atypical Mycobacteria , Maandschr Kindergeneesk 29:309 ( (Oct) ) 1961;.
Corpe, R.F.; Smith, E.E.; and Stergus, I.:  Death Due to Mycobacterium fortuitum , JAMA 177:262-263 ( (July 29) ) 1961;.
Kelly, D.J.; Weed, L.A.; and Lipscomb, P.R.:  Infection of Tendon Sheaths, Bursae, Joints and Soft Tissues by Acid-Fast Bacilli Other Than Tubercle Bacilli , J Bone Joint Surg 45A:327-336 ( (March) ) 1963;.
Merckx, J.J.; Karlson, A.G.; and Carr, D.T.:  Disease in Man Associated With Unclassified Acid-Fast Bacteria , Proc Mayo Clin 38:271-279 ( (July) ) 1963;.
Wood, L.D.; Buhler, V.B.; and Pollak, A.:  Human Infection with the "Yellow" Acid Fast Bacillus: A Report of 15 Additional Cases , Amer Rev Tuberc , 73:917-929 ( (June) ) 1956;.
Corpe, R.F., and Stergus, I:  Is the Histopathology of Non-photochromogenic Mycobacterial Infections Distinguishable From That Caused by Mycobacterium tuberculosis? Amer Rev Resp Dis 87:289-291 ( (Feb) ) 1963;.
American Trudeau Society Committee on Therapy:  The Effect of Cortisone and/or Corticotropin on Tuberculosis in Man , Amer Rev Tuberc 66:254-256, 1952;.

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Runyon, E.H.:  Anonymous Mycobacteria in Pulmonary Disease , Med Clin N Amer 43:273-290 ( (Jan) ) 1959;.
Slooff, J.P.:  Atypical Mycobacteria , Maandschr Kindergeneesk 29:309 ( (Oct) ) 1961;.
Corpe, R.F.; Smith, E.E.; and Stergus, I.:  Death Due to Mycobacterium fortuitum , JAMA 177:262-263 ( (July 29) ) 1961;.
Kelly, D.J.; Weed, L.A.; and Lipscomb, P.R.:  Infection of Tendon Sheaths, Bursae, Joints and Soft Tissues by Acid-Fast Bacilli Other Than Tubercle Bacilli , J Bone Joint Surg 45A:327-336 ( (March) ) 1963;.
Merckx, J.J.; Karlson, A.G.; and Carr, D.T.:  Disease in Man Associated With Unclassified Acid-Fast Bacteria , Proc Mayo Clin 38:271-279 ( (July) ) 1963;.
Wood, L.D.; Buhler, V.B.; and Pollak, A.:  Human Infection with the "Yellow" Acid Fast Bacillus: A Report of 15 Additional Cases , Amer Rev Tuberc , 73:917-929 ( (June) ) 1956;.
Corpe, R.F., and Stergus, I:  Is the Histopathology of Non-photochromogenic Mycobacterial Infections Distinguishable From That Caused by Mycobacterium tuberculosis? Amer Rev Resp Dis 87:289-291 ( (Feb) ) 1963;.
American Trudeau Society Committee on Therapy:  The Effect of Cortisone and/or Corticotropin on Tuberculosis in Man , Amer Rev Tuberc 66:254-256, 1952;.
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