Read before the session on transplantation of the Fourth Multiple Discipline Research Forum during the 113th annual convention of the American Medical Association, San Francisco, June 24, 1964.
Reprint requests to 300 Pasteur Dr, Palo Alto, Calif (Dr. Kountz).
From the Department of Surgery, Stanford University School of Medicine, Palo Alto, Calif.
The recipient of a renal transplant who is not genetically identical with the donor immediately falls victim of a new disease: renal homotransplant or renal-heterotransplant rejection. Since measures to induce specific immunologic tolerance to renal homotransplants are as yet unavailable, survival of the recipient is dependent upon effective therapy of his new disease.
The long-term results in both man and animals for experimental use whose survivals have depended on a single life-sustaining renal homotransplant have been poor.12 Some died from overdosage of the immunosuppressive drugs while the transplant exhibited good function, and others of homotransplant rejection from inadequate therapy. It has been suggested that the usual parameters of renal function were inadequate for early detection and monitoring of the immunologic reaction in renal homotransplants, especially in modified recipients.2-4 The usual dosage guide of immunosuppressive-drug therapy in renal homotransplantation has been a balance between toxicity, chiefly on the hematopoietic
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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