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April 20, 1964, Vol 188, No. 3 >
CLINICAL SCIENCE | April 20, 1964

The Biomedical Aspects of Lasers

Leon Goldman, MD; Donald J. Blaney, MD, PhD; Alan Freemond, MD
[+] Author Affiliations

Peter Hornby, Cincinnati

From the Laser Laboratories, Medical Center, University of Cincinnati, and Children's Hospital Research Foundation.


JAMA. 1964;188(3):302-306. doi:10.1001/jama.1964.03060290106036
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References

THERE IS much to interest the physician in the development of that fascinating instrument of modern physics, the laser. Although the first working laser was produced as late as July, 1960,1 laser development is now one of the greatest research fields of modern science. However, except for a few exceptions in the biomedical and microwelding fields, it remains a laboratory tool for scientific research. It is to medicine that most research workers in laser technology look for immediate practical developments, although up to the present there has not been much investigation of lasers in the field of medicine.

The laser produces a beam of coherent electromagnetic radiation of a sharply defined wavelength in that region of the spectrum broadly described as optical. This range includes the near-violet, the visible, and the near and far regions in the infrared. The term "coherence" is to be emphasized because it is an

REFERENCES

1 +
Townes, C.H.:  Optical Masers and Their Possible Applications to Biology , Biophys J 2:325 ( (March) ) 1962;.
2 +
Goldman, L.; Hornby, P.; and Solsman, J.:  Design for Complete Medical Laser Laboratory , to be presented at 16th Annual Conference on Engineering in Medicine and Biology, Baltimore, Nov 18, 1963.
3 +
Zaret, M.M., et al:  Ocular Lesions Produced by Optical Maser (Laser) , Science 134:1525 ( (Nov) ) 1961;.
4 +
Solon, L.R.:  Occupational Safety With Laser (Optical Maser) Beams , Arch Environ Health (Chicago) 6:414-417 ( (March) ) 1963;.
5 +
Grosof, C.: Personal communication to the author.
6 +
Campbell, C.J., et al:  Experimental Laser Retina Coagulator , presented before Optical Society of America, March 17, 1962.
7 +
Schepens, C.: Personal communication to the author.
8 +
Straub, H.W.: Protection of Human Eye From Laser Radiation , US Army Materiel Command, Harry Diamond Laboratories, TR-1153.
9 +
Goldman, L., et al:  Effect of Laser Beam on Skin , J Invest Derm 40:121 ( (March) ) 1963;.
10 +
Goldman, L., et al:  Pathology of Laser Beam Reaction on Skin , Nature (London) 97:912 ( (March 2) ) 1963;.
11 +
Goldman, L., et al:  Effect of Laser Beam on Cytological Preparations , J Invest Derm , to be published.
12 +
Goldman, L.:  Derzeitige untersuchungen von Dermatologischem Interesse mit dem Laser , Der Hautarzt , to be published.
13 +
Fine, J.M., et al:  Effects of Laser Radiation on Skin of Syrian Hamster , J Invest Derm 40:123 ( (March) ) 1963;.
14 +
McGuff, P.E.: Personal communication to the author.
15 +
Goldman, J.; Hornby, P.; and Long, C.:  Effect of Laser on Skin: III. Transmission of Laser Beams Through Fiber Optics , J Invest Derm , to be published.
16 +
Mauer, A.: Personal communication to the author.
17 +
Bessis, M., et al:  Irradiation des organites cellulaire à l'aide d'un Laser à rubis , C. R. Acad Sci (Paris) 255:1010 ( (July 30) ) 1962;.
18 +
Saks, N.M., and Roth, C.A.:  Ruby Laser as Microsurgical Instrument , Science 141:46-47 ( (July 5) ) 1963;.
19 +
Chamberlin, E.C., and Rounds, D.E.:  Preliminary Observation of Effects of Laser Irradiation on Cell Growth in Tissue Cultures , presented at Second Laser Conference, Northeastern University, Boston, Aug 1, 1963.
20 +
Loper, J.C., and Schechter, E.: Personal communication to the author.
21 +
Sucsy, L.G.: Masers and Lasers , Cambridge, Mass: Harvard University Graduate School of Business Administration, 1962;, p 164.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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1 +
Townes, C.H.:  Optical Masers and Their Possible Applications to Biology , Biophys J 2:325 ( (March) ) 1962;.
2 +
Goldman, L.; Hornby, P.; and Solsman, J.:  Design for Complete Medical Laser Laboratory , to be presented at 16th Annual Conference on Engineering in Medicine and Biology, Baltimore, Nov 18, 1963.
3 +
Zaret, M.M., et al:  Ocular Lesions Produced by Optical Maser (Laser) , Science 134:1525 ( (Nov) ) 1961;.
4 +
Solon, L.R.:  Occupational Safety With Laser (Optical Maser) Beams , Arch Environ Health (Chicago) 6:414-417 ( (March) ) 1963;.
5 +
Grosof, C.: Personal communication to the author.
6 +
Campbell, C.J., et al:  Experimental Laser Retina Coagulator , presented before Optical Society of America, March 17, 1962.
7 +
Schepens, C.: Personal communication to the author.
8 +
Straub, H.W.: Protection of Human Eye From Laser Radiation , US Army Materiel Command, Harry Diamond Laboratories, TR-1153.
9 +
Goldman, L., et al:  Effect of Laser Beam on Skin , J Invest Derm 40:121 ( (March) ) 1963;.
10 +
Goldman, L., et al:  Pathology of Laser Beam Reaction on Skin , Nature (London) 97:912 ( (March 2) ) 1963;.
11 +
Goldman, L., et al:  Effect of Laser Beam on Cytological Preparations , J Invest Derm , to be published.
12 +
Goldman, L.:  Derzeitige untersuchungen von Dermatologischem Interesse mit dem Laser , Der Hautarzt , to be published.
13 +
Fine, J.M., et al:  Effects of Laser Radiation on Skin of Syrian Hamster , J Invest Derm 40:123 ( (March) ) 1963;.
14 +
McGuff, P.E.: Personal communication to the author.
15 +
Goldman, J.; Hornby, P.; and Long, C.:  Effect of Laser on Skin: III. Transmission of Laser Beams Through Fiber Optics , J Invest Derm , to be published.
16 +
Mauer, A.: Personal communication to the author.
17 +
Bessis, M., et al:  Irradiation des organites cellulaire à l'aide d'un Laser à rubis , C. R. Acad Sci (Paris) 255:1010 ( (July 30) ) 1962;.
18 +
Saks, N.M., and Roth, C.A.:  Ruby Laser as Microsurgical Instrument , Science 141:46-47 ( (July 5) ) 1963;.
19 +
Chamberlin, E.C., and Rounds, D.E.:  Preliminary Observation of Effects of Laser Irradiation on Cell Growth in Tissue Cultures , presented at Second Laser Conference, Northeastern University, Boston, Aug 1, 1963.
20 +
Loper, J.C., and Schechter, E.: Personal communication to the author.
21 +
Sucsy, L.G.: Masers and Lasers , Cambridge, Mass: Harvard University Graduate School of Business Administration, 1962;, p 164.

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