Pheochromocytoma Without Hypertension: Title and subTitle BreakReport of a Patient With Acromegaly

Marcel T. Kahn, MD; David A. Mullon, MD

[+] Author Affiliations

The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

Tucson, Ariz

From the Medical Service, Veterans Hospital.

JAMA. 1964;188(1):74-75. doi:10.1001/jama.1964.03060270080022

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References

ABSTRACT

ABSTRACT | REFERENCES

IN 1950, almost 30 years after the first description of pheochromocytoma, Smithwick¹ was able to collect only 270 cases from the literature. Since then an ever increasing number of cases has been reported, indicating a growing awareness of this disease. Many excellent reviews have pointed out the diagnostic difficulties so frequently encountered.

A case of pheochromocytoma recently observed in a patient with chronic acromegaly should serve to demonstrate a few of these diagnostic difficulties. In addition, the combination of pheochromocytoma with chronic pituitary adenoma may stimulate some etiological considerations.

Report of a Case In 1944, a 23-year-old white male developed signs and symptoms of acromegaly. In 1945, enlargement and erosion of the sella turcica were noted on x-rays, characteristic visual field defects were found, and the patient received radiation therapy for a pituitary adenoma. Thirteen years later, in April and in June, 1960, he had two brief episodes of

REFERENCES

ABSTRACT | REFERENCES

Smithwick, R.H., et al: Pheochromocytoma , New Eng J Med 242:252, 1950;.

Cahill, G.F.: Pheochromocytoma , Bull NY Acad Med 29:749, 1953;.

Kvale, W.F., et al: Present Day Diagnosis and Treatment of Pheochromocytoma , JAMA 164:854, 1957;.

Poliquin, P.A., and Dupuis, P.: Pheochromocytoma Without Hypertension , abstracted, JAMA 142:1021, 1960;.

Kline, I.K.: Myocardial Alterations With Pheochromocytoma , Amer J Path 38:539, 1961;.

Futterweit, W.; Allen, L.; and Moser, M.: Pheochromocytoma With Radioactive Iodine Uptake and Electrocardiographic Abnormalities , Metabolism 11:589, 1962;.

Goodall, McC, and Stone, C.: Adrenalin and Noradrenalin Producing Tumors , Ann Surg 151:391, 1960;.

Moon, H.D., et al: Neoplasms on Rats Treated With Pituitary Growth Hormone: I. Pulmonary and Lymphatic Tumors , Cancer Res 10:297, 1950;.

Moon, H.D., et al: Neoplasms on Rats Treated With Pituitary Growth Hormone: II. Adrenal Glands , Cancer Res 10:364, 1950;.

Moon, H.D., et al: Neoplasms on Rats Treated With Pituitary Growth Hormone: III. Reproductive Organs , Cancer Res 10:549, 1950;.

Moon, H.D., et al: Neoplasms on Rats Treated With Pituitary Growth Hormone: V. Absence of Neoplasms in Hypophysectomized Rats , Cancer Res 11:535, 1951;.

Lupulescou, A.: Les phéochromocytomes expérimentaux , Ann Endocr (Paris) 22:459, 1962;.

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