0
January 4, 1964, Vol 187, No. 1 >
Original Contributions | January 4, 1964

Pheochromocytoma—Anesthetic and Surgical Considerations

D. LeRoy Crandell, MD; Richard T. Myers, MD
[+] Author Affiliations

Read before the Section on Anesthesiology during the 112th Annual Meeting of the American Medical Association, Atlantic City, NJ, June 17, 1963.


JAMA. 1964;187(1):12-16. doi:10.1001/jama.1964.03060140018004
Text Size: A A A
Published online
Article
References

Eleven consecutive cases of pheochromocytoma were successfully diagnosed and surgically cured. The rational anesthetic management of a patient with pheochromocytoma should be based on a firm foundation of applied pharmacology. Cardiovascular control is best maintained symptomatically using phentolamine (Regitine) hydrochloride to control excessive hypertension, and with appropriate vasopressors, whole blood or plasma and possible cortisone acetate, to combat hypotension after the tumor is removed. The advantages associated with the transabdominal surgical approach are stressed. The patient with pheochromocytoma can tolerate anesthesia and the associated surgical procedure well through the combined efforts of the anesthesiologist and surgeon in executing their specific responsibilities.

REFERENCES

1 +
Swan, H.J.C.:  Effect of Noradrenaline on Human Circulation , Lancet 2:508-510, 1949;.
2 +
Nickerson, M.:  Blockade of Actions of Adrenaline and Noradrenaline , Pharmacol Rev 11:443, 1959;.
3 +
Page, I.H., and Taylor, R.D.:  Augmentation of Vasoactive Substances , Circulation 1:1233, 1950;.
4 +
Kurland, G.S., and Freeberg, A.S.:  Potentiating Effect of ACTH and of Cortisone on Pressor Response of Intravenous Infusion of 1-Norepinephrine , Proc Soc Exp Biol Med 78:28-31 ( (Oct) ) 1951;.
5 +
Friedman, S.M.; Friedman, C.L.; and Nakashuna, M.:  Cationic Shifts and Blood Pressure Regulations , Circ Res 5:261-267 ( (May) ) 1957;.
6 +
Burn, J.H., and Rand, M.J.:  Fall of Blood Pressure After Noradrenaline Infusion and Its Treatment by Pressor Agents , Brit Med J 1:394, 1959;.
7 +
Burn, J.H., and Rand, M.J.:  New Observations on Sympathetic Postganglionic Mechanism , Amer J Med 29:1002, 1960;.
8 +
Costa, E., et al:  Role for Ganglionic Norepinephrine in Sympathetic Synaptic Transmission , Science 133:1822, 1961;.
9 +
Finnerty, F.A., Jr.; Buchholz, J.H., and Guillaudeu, R.L.:  Blood Volumes and Plasma Protein During Levarterenol-Induced Hypertension , J Clin Invest 37:425-429, 1958;.
10 +
Brunjes, S.; Johns, V.J. Jr.; and Crane, M.G.:  Pheochromocytoma: Postoperative Shock and Blood Volume , New Eng J Med 262:393-396, 1960;.
11 +
Crandell, D.L.:  Pharmacology of Pheochromocytoma , Southern Med J 56:885, 1963;.

First Page Preview

First page PDF preview

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Swan, H.J.C.:  Effect of Noradrenaline on Human Circulation , Lancet 2:508-510, 1949;.
2 +
Nickerson, M.:  Blockade of Actions of Adrenaline and Noradrenaline , Pharmacol Rev 11:443, 1959;.
3 +
Page, I.H., and Taylor, R.D.:  Augmentation of Vasoactive Substances , Circulation 1:1233, 1950;.
4 +
Kurland, G.S., and Freeberg, A.S.:  Potentiating Effect of ACTH and of Cortisone on Pressor Response of Intravenous Infusion of 1-Norepinephrine , Proc Soc Exp Biol Med 78:28-31 ( (Oct) ) 1951;.
5 +
Friedman, S.M.; Friedman, C.L.; and Nakashuna, M.:  Cationic Shifts and Blood Pressure Regulations , Circ Res 5:261-267 ( (May) ) 1957;.
6 +
Burn, J.H., and Rand, M.J.:  Fall of Blood Pressure After Noradrenaline Infusion and Its Treatment by Pressor Agents , Brit Med J 1:394, 1959;.
7 +
Burn, J.H., and Rand, M.J.:  New Observations on Sympathetic Postganglionic Mechanism , Amer J Med 29:1002, 1960;.
8 +
Costa, E., et al:  Role for Ganglionic Norepinephrine in Sympathetic Synaptic Transmission , Science 133:1822, 1961;.
9 +
Finnerty, F.A., Jr.; Buchholz, J.H., and Guillaudeu, R.L.:  Blood Volumes and Plasma Protein During Levarterenol-Induced Hypertension , J Clin Invest 37:425-429, 1958;.
10 +
Brunjes, S.; Johns, V.J. Jr.; and Crane, M.G.:  Pheochromocytoma: Postoperative Shock and Blood Volume , New Eng J Med 262:393-396, 1960;.
11 +
Crandell, D.L.:  Pharmacology of Pheochromocytoma , Southern Med J 56:885, 1963;.

Letters

Submit a Letter
CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2012 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems