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EMOTION AND GASTRIC ACTIVITY FREE

Charlyne T. Seymour, Ph.D.; Joseph A. Weinberg, M.D.
[+] Author Affiliations

Long Beach, Calif.

Staff Psychologist, Veterans Administration Hospital, and Associate Clinical Professor of Psychology, University of California at Los Angeles (Dr. Seymour); Chief, Surgical Service, Veterans Administration Hospital, and Clinical Professor of Surgery, University of California at Los Angeles Medical School (Dr. Weinberg).


JAMA. 1959;171(9):1193-1195. doi:10.1001/jama.1959.03010270029007
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The emotional responses of 24 men were observed before and after vagotomy for duodenal ulcers. The surgical treatment was necessitated by hemorrhage, intractable pain, obstruction, or combinations of these conditions. The observations included fluoroscopy, roentgenograms, and determinations of the acidity and volume of gastric juice. Emotions were aroused by stressful interviews which proceeded with minimum delay to the patient's personal problems. These interviews elicited the same overt signs of psychological distress after the operation as they had before, but they no longer caused the increases of gastric secretion and motility seen in subjects with intact vagi. Since vagotomy was followed by healing of the ulcer in every instance, these findings strengthen the conviction that emotional influences play a role in the causation of duodenal ulcer.

REFERENCES

Bell, A.; Trosman, H.; and Ross, D.:  Use of Projective Techniques in Investigation of Emotional Aspects of General Medical Disorders: 1. Rorschach Method , J. Proj. Tech. 16:428-443 ( (Dec.) ) 1952;.
Brown, M., and others:  Personality Factors in Duodenal Ulcer: Rorschach Study , Psychosom. Med 12:1-5 ( (Jan.) -Feb.) 1950;.
Dragstedt, L. R.:  Vagotomy for Gastroduodenal Ulcer , Ann. Surg. 122:973-989 ( (Dec.) ) 1945;.
Engel, G. L., and Reichsman, F.:  Spontaneous and Experimentally Induced Depressions in Infant with Gastric Fistula: Contribution to Problem of Depression , J. Am. Psychoanal. A. 4:428-452 ( (July) ) 1956;.
Gaskill, H. S.:  Personality Study of Patients with Organic Digestive Tract Disease , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 255-260.
Katz, M. M.:  Psychodynamics of Peptic Ulcer Pathogenesis in Hospitalized Schizophrenic Patients , Psychosom. Med. 16:47-54 ( (Jan.) -Feb.) 1954;.
Osborne, R. T., and Sanders, W. B.:  Rorschach Characteristics of Duodenal Ulcer Patients , J. Clin. Psychol. 6:258-262 ( (July) ) 1950;.
Streitfeld, H. S.:  Specificity of Peptic Ulcer to Intense Oral Conflicts , Psychosom. Med. 16:315-326 ( (July) Aug.) 1954;.
Wolf, S.:  Experimental Observation on Changes in Emotional State and Physiologic Disturbances in Gastrointestinal Tract , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 225-247.
Hunt, J. N.:  Inhibition of Gastric Emptying and Secretion in Patients with Duodenal Ulcer , Lancet 1:132-134 ( (Jan. 19) ) 1957;.
Schoen, A. M.:  Effect of Vagotomy on Human Gastric Secretion , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 168-181.
Stempien, S. J., and Weinberg, J. A.:  Recurrence of Ulcer After Vagotomy , J. A. M. A. 152:1593-1595 ( (Aug. 22) ) 1953;.
Lorber, S. H.:  Inhibition of Gastric Secretion in Ulcer Patients with Debutoline , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 34-39.
Roth, J. L. d'A.:  Rational Use of Various Gastric Analysis Procedures in Study of Gastric Function , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 54-63.
Rovelstad, R. A.:  Continuously Recorded in Situ pH of Gastric and Duodenal Contents in Patients With and Without Duodenal Ulcers , Gastroenterology 31:530-537 ( (Nov.) ) 1956;.
Weinberg, J. A.; Campbell, G. W.; and Voelker, R. B.:  Vagus Nerve Section in Treatment of Peptic Ulcer: Abdominal Versus Thoracic Approach , J. Thoracic Surg. 17:743-755 ( (Dec.) ) 1948;.
Wolff, P., and Levine, J.:  Nocturnal Gastric Secretions of Ulcer and Nonulcer Patients Under Stress , Psychosom. Med. 17:218-226 ( (May) -June) 1955;.
Weisman, A. D.:  Study of Psychodynamics of Duodenal Ulcer Exacerbations with Special Reference to Treatment and Problem of "Specificity," Psychosom. Med. 18:242 ( (Jan.) -Feb.) 1956;.
Siegel, S.: Nonparametric Statistics: For the Behavioral Sciences , New York, McGraw-Hill Book Company, Inc., 1956;, pp. 68-75.

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Bell, A.; Trosman, H.; and Ross, D.:  Use of Projective Techniques in Investigation of Emotional Aspects of General Medical Disorders: 1. Rorschach Method , J. Proj. Tech. 16:428-443 ( (Dec.) ) 1952;.
Brown, M., and others:  Personality Factors in Duodenal Ulcer: Rorschach Study , Psychosom. Med 12:1-5 ( (Jan.) -Feb.) 1950;.
Dragstedt, L. R.:  Vagotomy for Gastroduodenal Ulcer , Ann. Surg. 122:973-989 ( (Dec.) ) 1945;.
Engel, G. L., and Reichsman, F.:  Spontaneous and Experimentally Induced Depressions in Infant with Gastric Fistula: Contribution to Problem of Depression , J. Am. Psychoanal. A. 4:428-452 ( (July) ) 1956;.
Gaskill, H. S.:  Personality Study of Patients with Organic Digestive Tract Disease , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 255-260.
Katz, M. M.:  Psychodynamics of Peptic Ulcer Pathogenesis in Hospitalized Schizophrenic Patients , Psychosom. Med. 16:47-54 ( (Jan.) -Feb.) 1954;.
Osborne, R. T., and Sanders, W. B.:  Rorschach Characteristics of Duodenal Ulcer Patients , J. Clin. Psychol. 6:258-262 ( (July) ) 1950;.
Streitfeld, H. S.:  Specificity of Peptic Ulcer to Intense Oral Conflicts , Psychosom. Med. 16:315-326 ( (July) Aug.) 1954;.
Wolf, S.:  Experimental Observation on Changes in Emotional State and Physiologic Disturbances in Gastrointestinal Tract , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 225-247.
Hunt, J. N.:  Inhibition of Gastric Emptying and Secretion in Patients with Duodenal Ulcer , Lancet 1:132-134 ( (Jan. 19) ) 1957;.
Schoen, A. M.:  Effect of Vagotomy on Human Gastric Secretion , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 168-181.
Stempien, S. J., and Weinberg, J. A.:  Recurrence of Ulcer After Vagotomy , J. A. M. A. 152:1593-1595 ( (Aug. 22) ) 1953;.
Lorber, S. H.:  Inhibition of Gastric Secretion in Ulcer Patients with Debutoline , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 34-39.
Roth, J. L. d'A.:  Rational Use of Various Gastric Analysis Procedures in Study of Gastric Function , in Postgraduate Gastroenterology , edited by H. L. Bockus, Philadelphia, W. B. Saunders Company, 1950;, pp. 54-63.
Rovelstad, R. A.:  Continuously Recorded in Situ pH of Gastric and Duodenal Contents in Patients With and Without Duodenal Ulcers , Gastroenterology 31:530-537 ( (Nov.) ) 1956;.
Weinberg, J. A.; Campbell, G. W.; and Voelker, R. B.:  Vagus Nerve Section in Treatment of Peptic Ulcer: Abdominal Versus Thoracic Approach , J. Thoracic Surg. 17:743-755 ( (Dec.) ) 1948;.
Wolff, P., and Levine, J.:  Nocturnal Gastric Secretions of Ulcer and Nonulcer Patients Under Stress , Psychosom. Med. 17:218-226 ( (May) -June) 1955;.
Weisman, A. D.:  Study of Psychodynamics of Duodenal Ulcer Exacerbations with Special Reference to Treatment and Problem of "Specificity," Psychosom. Med. 18:242 ( (Jan.) -Feb.) 1956;.
Siegel, S.: Nonparametric Statistics: For the Behavioral Sciences , New York, McGraw-Hill Book Company, Inc., 1956;, pp. 68-75.
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