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MANAGEMENT OF CHRONIC URTICARIA FREE

Ben C. Eisenberg, M.D.
[+] Author Affiliations

Read in the Session on Allergy before the Section on Miscellaneous Topics at the 107th Annual Meeting of the American Medical Association, San Francisco, June 27, 1958.


Huntington Park, Calif.

From the Medical Department, University of Southern California School of Medicine, and the Allergy Clinic, Los Angeles County General Hospital.


JAMA. 1959;169(1):14-20. doi:10.1001/jama.1959.03000180016005
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Analysis of 50 cases of chronic urticaria revealed a large variety of foods, drugs, infections, inhalants, and other items as possible causes of the disorder. The patients ranged in age from 8 to 73 years, and some had been afflicted as long as 22 years. There was much overlapping of etiological diagnoses. Emotional difficulties appeared to be significant in 32 patients, but among these there were only 6 in whom no other factors were clearly operative. Patients were encouraged to discuss domestic and occupational situations that might be emotionally charged. When the cause eludes recognition or cannot be obviated, symptomatic treatment is necessary. In this series it usually consisted of hydroxyzine hydrochloride, given orally in doses of 10 to 25 mg. three or four times a day, with antihistamines. Ephedrine hydrochloride was occasionally given by mouth and seldom by injection. Injection of epinephrine may be required in an occasional patient in whom angioneurotic edema threatens life by involving the pharyngolaryngeal areas.

REFERENCES

Sheldon, J. M.; Mathews, K. P.; and Lovell, R. G.:  Vexing Urticaria Problem: Present Concepts of Etiology and Management , J. Allergy 25:525-560 ( (Nov.) ) 1954;.
Swinny, B.:  Atopic Factor in Urticaria , South. M. J. 34:855-858 ( (Aug.) ) 1941;.
Brown, E. A.:  Drug Allergy , Quart. Rev. Allergy 7:51-82 ( (March) ) 1953;
 Problems of Drug Allergy , J. A. M. A. 157:814-819 ( (March 5) ) 1955;.
Strauss, M. B.; Siegel, B. B.; and Blumstein, G.:  Allergenic Food Extracts: I. Methods of Preparation , J. Allergy 29:173-180 ( (March) ) 1958;.
Cohen, S. B., and Criep, L. H.:  Urticaria and Angioedema in Association with Amebiasis , Am. Pract. & Digest. Treat. 1:246-255 ( (March) ) 1950;.
Harris, R. H., and Mitchell, J. H.:  Chronic Urticaria due to Giardia Lamblia , Arch. Dermat. & Syph. 59:587-589 ( (May) ) 1949;.
Wilhelm, R.:  Urticaria Associated with Giardiasis lamblia , J. Allergy 28:351-353 ( (July) ) 1958;.
Mitchell, J. H.; Smith, D. L.; and Mayers, R. A.:  Is Chronic Urticaria an Allergic Disorder? Ann. Allergy 15:128-134 ( (March) -April) 1957;.
Wittkower, E., and Russell, B.: Emotional Factors in Skin Diseases , New York, Paul B. Hoeber, Inc., 1953;.
Bookman, R.:  Status of Corticotropin and Steroid Hormones in Therapy of Allergic Diseases , J. A. M. A. 165:-1950-1953 ( (Dec. 14) ) 1957;.
Eisenberg, B. C.:  Role of Tranquilizing Drugs in Allergy , J. A. M. A. 163:934-937 ( (March 16) ) 1957;.
Seneca, H.:  Hydroxyzine (Atarax) as Therapeutic Agent , Antibiotic Med. 4:25, 1957;.
Peshkin, M. M.:  Pitfalls of Skin Tests in Allergy , J. A. M. A. 157:820-823 ( (March 5) ) 1955;.
 Diagnostic Value of Skin Testing , editorial, PeshkinJ. A. M. A. 157:825 ( (March 5) ) 1955;.
Wittkower, E. D.:  Studies of Personality of Patients Suffering from Urticaria , Psychosom. Med. 15:116-126 ( (March) -April) 1953;.
Graham, D. T.; Wolf, S.; and Wolff, H. G.:  Change in Tissue Sensitivity Associated with Varying Life Situations and Emotions: Their Relevance to Allergy , J. Allergy 21:478-486 ( (Nov.) ) 1950;.
References 6 and 7.

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Sheldon, J. M.; Mathews, K. P.; and Lovell, R. G.:  Vexing Urticaria Problem: Present Concepts of Etiology and Management , J. Allergy 25:525-560 ( (Nov.) ) 1954;.
Swinny, B.:  Atopic Factor in Urticaria , South. M. J. 34:855-858 ( (Aug.) ) 1941;.
Brown, E. A.:  Drug Allergy , Quart. Rev. Allergy 7:51-82 ( (March) ) 1953;
 Problems of Drug Allergy , J. A. M. A. 157:814-819 ( (March 5) ) 1955;.
Strauss, M. B.; Siegel, B. B.; and Blumstein, G.:  Allergenic Food Extracts: I. Methods of Preparation , J. Allergy 29:173-180 ( (March) ) 1958;.
Cohen, S. B., and Criep, L. H.:  Urticaria and Angioedema in Association with Amebiasis , Am. Pract. & Digest. Treat. 1:246-255 ( (March) ) 1950;.
Harris, R. H., and Mitchell, J. H.:  Chronic Urticaria due to Giardia Lamblia , Arch. Dermat. & Syph. 59:587-589 ( (May) ) 1949;.
Wilhelm, R.:  Urticaria Associated with Giardiasis lamblia , J. Allergy 28:351-353 ( (July) ) 1958;.
Mitchell, J. H.; Smith, D. L.; and Mayers, R. A.:  Is Chronic Urticaria an Allergic Disorder? Ann. Allergy 15:128-134 ( (March) -April) 1957;.
Wittkower, E., and Russell, B.: Emotional Factors in Skin Diseases , New York, Paul B. Hoeber, Inc., 1953;.
Bookman, R.:  Status of Corticotropin and Steroid Hormones in Therapy of Allergic Diseases , J. A. M. A. 165:-1950-1953 ( (Dec. 14) ) 1957;.
Eisenberg, B. C.:  Role of Tranquilizing Drugs in Allergy , J. A. M. A. 163:934-937 ( (March 16) ) 1957;.
Seneca, H.:  Hydroxyzine (Atarax) as Therapeutic Agent , Antibiotic Med. 4:25, 1957;.
Peshkin, M. M.:  Pitfalls of Skin Tests in Allergy , J. A. M. A. 157:820-823 ( (March 5) ) 1955;.
 Diagnostic Value of Skin Testing , editorial, PeshkinJ. A. M. A. 157:825 ( (March 5) ) 1955;.
Wittkower, E. D.:  Studies of Personality of Patients Suffering from Urticaria , Psychosom. Med. 15:116-126 ( (March) -April) 1953;.
Graham, D. T.; Wolf, S.; and Wolff, H. G.:  Change in Tissue Sensitivity Associated with Varying Life Situations and Emotions: Their Relevance to Allergy , J. Allergy 21:478-486 ( (Nov.) ) 1950;.
References 6 and 7.
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